Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Jane Newcombe"'
Autor:
Khushboo Borah Slater, Martin Beyß, Ye Xu, Jim Barber, Catia Costa, Jane Newcombe, Axel Theorell, Melanie J Bailey, Dany J V Beste, Johnjoe McFadden, Katharina Nöh
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 3, Pp 1-18 (2023)
Abstract Metabolic flux is the final output of cellular regulation and has been extensively studied for carbon but much less is known about nitrogen, which is another important building block for living organisms. For the tuberculosis pathogen, this
Externí odkaz:
https://doaj.org/article/5bb60f4298fe4261b1609c783aff848a
Publikováno v:
Bio-Protocol, Vol 7, Iss 9 (2017)
The meningococcus (Neisseria meningitidis) remains an important threat to human health worldwide. This Gram-negative bacterium causes elevated disabilities and mortality in infected individuals. Despite several available vaccines, currently there is
Externí odkaz:
https://doaj.org/article/11a801f6802141778803f5cd7c8a7bbe
Autor:
Michelle M. C. Buckner, Jessica M. A. Blair, Roberto M. La Ragione, Jane Newcombe, Daniel J. Dwyer, Alasdair Ivens, Laura J. V. Piddock
Publikováno v:
mBio, Vol 7, Iss 6 (2016)
ABSTRACT For over 20 years, bacterial multidrug resistance (MDR) efflux pumps have been studied because of their impact on resistance to antimicrobials. However, critical questions remain, including why produce efflux pumps under non-antimicrobial tr
Externí odkaz:
https://doaj.org/article/c418bdbe44684db7a3104372910a266e
Autor:
Abdulaziz Alqasim, Richard Emes, Gemma Clark, Jane Newcombe, Roberto La Ragione, Alan McNally
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88374 (2014)
Extraintestinal pathogenic E. coli (ExPEC) are the major aetiological agent of urinary tract infections (UTIs) in humans. The emergence of the CTX-M producing clone E. coli ST131 represents a major challenge to public health worldwide. A recent study
Externí odkaz:
https://doaj.org/article/b0fd5dc1627b44d38dc18a0c4ecb4932
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e5940 (2009)
Despite the introduction of conjugated polysaccharide vaccines for many of the Neisseria meningitidis serogroups, neisserial infections continue to cause septicaemia and meningitis across the world. This is in part due to the difficulties in developi
Externí odkaz:
https://doaj.org/article/77e2eddf972740e08848343208b325f8
Autor:
Louise Tzung-Harn Hsieh, Belinda S. Hall, Jane Newcombe, Tom A. Mendum, Yagnesh Umrania, Michael J. Deery, Wei Q. Shi, Francisco J. Salguero, Rachel E Simmonds
Publikováno v:
bioRxiv
The drivers of tissue necrosis inMycobacterium ulceransinfection (Buruli ulcer disease) have historically been ascribed solely to the directly cytotoxic action of the diffusible exotoxin, mycolactone. However, its role in the clinically-evident vascu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c55428914d374d8851b176a493e922e2
https://europepmc.org/articles/PMC9980099/
https://europepmc.org/articles/PMC9980099/
Autor:
Khushboo Borah Slater, Martin Beyß, Ye Xu, Jim Barber, Catia Costa, Jane Newcombe, Axel Theorell, Melanie J Bailey, Dany J V Beste, Johnjoe McFadden, Katharina Nöh
Publikováno v:
Molecular systems biology 19(3), e11099 (2023). doi:10.15252/msb.202211099
Metabolic flux is the final output of cellular regulation and has been extensively studied for carbon but much less is known about nitrogen, which is another important building block for living organisms. For the tuberculosis pathogen, this is partic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a415fb784d768af7aa7728fb18438c20
https://doi.org/10.15252/msb.202211099
https://doi.org/10.15252/msb.202211099
Autor:
Khushboo Borah, Martin Beyß, Ye Xu, Jim Barber, Catia Costa, Jane Newcombe, Axel Theorell, Melanie J Bailey, Dany JV Beste, Johnjoe McFadden, Katharina Nöh
Metabolic flux is the final output of cellular regulation and has been extensively studied for carbon but much less is known about nitrogen, which is another important building block for living organisms. For the pathogen Mycobacterium tuberculosis (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e0157a01a8970097c52516d439882ba
https://doi.org/10.1101/2022.03.08.483448
https://doi.org/10.1101/2022.03.08.483448
Autor:
Kenny Lidberg, Sara Sigurlásdóttir, Ann-Beth Jonsson, Fanglei Zuo, Jane Newcombe, Johnjoe McFadden
Publikováno v:
Infection and Immunity
Neisseria meningitidis is the etiologic agent of meningococcal meningitis and sepsis. Initial colonization of meningococci in the upper respiratory tract epithelium is crucial for disease development. The colonization occurs in several steps and expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::990f76ed18a97d8f82af0fb691ebe52f
http://europepmc.org/articles/PMC8445170
http://europepmc.org/articles/PMC8445170
Autor:
Kalistyn H, Burley, Bonnie J, Cuthbert, Piyali, Basu, Jane, Newcombe, Ervin M, Irimpan, Robert, Quechol, Ilona P, Foik, David L, Mobley, Dany J V, Beste, Celia W, Goulding
Publikováno v:
ACS Infect Dis
Tuberculosis (TB) is the most lethal bacterial infectious disease worldwide. It is notoriously difficult to treat, requiring a cocktail of antibiotics administered over many months. The dense, waxy outer membrane of the TB-causing agent, Mycobacteriu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::67279b371ae5c1d089d0fb749e74a98f
https://pubmed.ncbi.nlm.nih.gov/33356117
https://pubmed.ncbi.nlm.nih.gov/33356117