Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Jane McGlade"'
Autor:
Sascha E. Dho, Nancy Silva-Gagliardi, Fabio Morgese, Etienne Coyaud, Emily Lamoureux, Donna M. Berry, Brian Raught, C. Jane McGlade
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-18 (2019)
Abstract MIB1 belongs to the RING domain containing family of E3 ubiquitin ligases. In vertebrates, MIB1 plays an essential role in activation of Notch signaling during development, through the ubiquitination and endocytosis of Notch ligands. More re
Externí odkaz:
https://doaj.org/article/9b094eda6c774a899372bfb15aca2c6c
Effect of JPO2 on cell death induced by serum starvation, chemotherapeutics and radiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b0edbe01d6da4b6a643767ab9509381
https://doi.org/10.1158/0008-5472.22410966
https://doi.org/10.1158/0008-5472.22410966
JPO2 has limited effects on MB cell proliferation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87ff7ef3bd3fd9c606812455dad6c8e2
https://doi.org/10.1158/0008-5472.22410969
https://doi.org/10.1158/0008-5472.22410969
AKT inhibition does not alter JPO2 mRNA levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::639afc004a69f7a2a75f2ed90b3934a7
https://doi.org/10.1158/0008-5472.22410951
https://doi.org/10.1158/0008-5472.22410951
Correlation of JPO2 and LEDGF/p75 transcript levels in MB subtypes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bf31928b3ced8631dee55bc97819ff4
https://doi.org/10.1158/0008-5472.22410948
https://doi.org/10.1158/0008-5472.22410948
Supplemental Figure Legends 1-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca484b662caf11f7b905b2566bd08de6
https://doi.org/10.1158/0008-5472.22410945
https://doi.org/10.1158/0008-5472.22410945
JPO2 is a LEDGF/p75 responsive gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6456238d3c19c09858447cc348e8a31d
https://doi.org/10.1158/0008-5472.22410960.v1
https://doi.org/10.1158/0008-5472.22410960.v1
LEDGF increases JPO2 protein levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea040288683632b05bb6078026880c1
https://doi.org/10.1158/0008-5472.22410957
https://doi.org/10.1158/0008-5472.22410957
LEDGF promotes MB cell survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c5c7743a5ea1ecc00a9f199c7f87a1d
https://doi.org/10.1158/0008-5472.22410963
https://doi.org/10.1158/0008-5472.22410963
Substantial evidence links Myc–PI3K/AKT signaling to the most aggressive subtype of medulloblastoma and this axis in medulloblastoma therapy. In this study, we advance understanding of how Myc–PI3K/AKT signaling contributes to this malignancy, sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54b3a9d1fda78838848888e62544df47
https://doi.org/10.1158/0008-5472.c.6508116.v1
https://doi.org/10.1158/0008-5472.c.6508116.v1