Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jane M. Landolin"'
Autor:
Steven J. Knapp, Jane M. Landolin, Nicholas Maurer, David Kudrna, David R. Rank, Beth Shapiro, Doreen Ware, Joseph W. Karalius, Ting Hon, Paul Peluso, Greg Young, Kristin Mars, Cynthia C. Steiner, Yu-Chih Tsai, Michael A. Hardigan
Publikováno v:
Scientific Data, Vol 7, Iss 1, Pp 1-11 (2020)
Scientific data, vol 7, iss 1
Scientific Data
Scientific data, vol 7, iss 1
Scientific Data
The PacBio® HiFi sequencing method yields highly accurate long-read sequencing datasets with read lengths averaging 10–25 kb and accuracies greater than 99.5%. These accurate long reads can be used to improve results for complex applications such
Autor:
Jane M. Landolin, Amanda Miller, Omid Shams Solari, Adam Harvey, Christina Curtis, Peter J. Tonellato, Stefanie S. Jeffrey, Nathan Boley, Anshul Kundaje, George W. Sledge, Paul G. Giresi, Artur Jaroszewicz, Erik Gafni, Mouadh Barbirou
Publikováno v:
Cancer Research. 81:2105-2105
Introduction: Chromatin accessibility and cell-free DNA fragmentation patterns can be used to identify epigenomic mechanisms (Sharma et al. 2010) and infer cell-types contributing to cfDNA in pathological states such as cancer (Snyder et al. 2016; Ul
Autor:
Chris Zaleski, Brenton R. Graveley, Wei Lin, Thomas R. Gingeras, Peter Cherbas, Srinka Ghosh, Philipp Kapranov, Alexander Dobin, Joseph W. Carlson, Lucy Cherbas, Li Yang, Carrie A. Davis, Yi Zou, Johnny Roberts, Justen Andrews, Kim Bell, Michael O. Duff, Roger A. Hoskins, Jeong Hyeon Choi, Jane M. Landolin, Laura Langton, Michael R. Brent, Jacqueline Dumais, Dayu Zhang, Anastasia Samsonova, Marijke J. van Baren, Aaron Tenney, Norbert Perrimon, Haixu Tang, Brian D. Eads, Aarron T. Willingham, Thomas C. Kaufman, Susan E. Celniker
Publikováno v:
Genome Research. 21:301-314
Drosophila melanogaster cell lines are important resources for cell biologists. Here, we catalog the expression of exons, genes, and unannotated transcriptional signals for 25 lines. Unannotated transcription is substantial (typically 19% of euchro-
Autor:
Hazuki Takahashi, Timo Lassmann, Jane M. Landolin, Joseph W. Carlson, Kenneth H. Wan, Jeremy E. Sandler, Charles Yu, Justen Andrews, Thomas C. Kaufman, Benjamin W. Booth, Peter J. Bickel, Piero Carninci, Dayu Zhang, Li Yang, James B. Brown, Brenton R. Graveley, Nathan Boley, Roger A. Hoskins, Susan E. Celniker
Publikováno v:
Genome Research. 21:182-192
Core promoters are critical regions for gene regulation in higher eukaryotes. However, the boundaries of promoter regions, the relative rates of initiation at the transcription start sites (TSSs) distributed within them, and the functional significan
Autor:
Roger A. Hoskins, Peter Cherbas, Brian B. Tuch, Lucy Cherbas, Michael R. Brent, Wei Lin, Laura Langton, Dayu Zhang, James B. Brown, Thomas R. Gingeras, Aarron T. Willingham, Alexander Dobin, Brenton R. Graveley, Susan E. Celniker, Nathan Boley, Carlo G. Artieri, Steven E. Brenner, Nicolas R. Mattiuzzo, Carrie A. Davis, Marco Blanchette, Jeremy E. Sandler, David Sturgill, Sandrine Dudoit, Brian Oliver, Benjamin W. Booth, Peter J. Bickel, Renhua Li, Yu Zhang, Norbert Perrimon, Phil Kapranov, David Scott Miller, Ann S. Hammonds, Marijke J. van Baren, Yi Zou, Richard E. Green, Joseph W. Carlson, Lichun Jiang, Jane M. Landolin, Chris Zaleski, Li Yang, Kenneth H. Wan, Thomas C. Kaufman, Brian D. Eads, John H. Malone, Angela N. Brooks, Michael O. Duff, Justen Andrews
Publikováno v:
Nature
Drosophila melanogaster is one of the most well studied genetic model organisms, nonetheless its genome still contains unannotated coding and non-coding genes, transcripts, exons, and RNA editing sites. Full discovery and annotation are prerequisites
Autor:
Shelley Force Aldred, Catherine Medina, Hennady P. Shulha, Nathan D. Trinklein, Jane M. Landolin, Richard M. Myers, Zhiping Weng, David S. Johnson
Publikováno v:
Genome Research. 20:890-898
Promoters are important regulatory elements that contain the necessary sequence features for cells to initiate transcription. To functionally characterize a large set of human promoters, we measured the transcriptional activities of 4575 putative pro
Autor:
Brenton R. Graveley, Steven E. Brenner, Li Yang, Jeremy E. Sandler, Mohan Bolisetty, Angela N. Brooks, Jane M. Landolin, Gemma E. May, Michael O. Duff, Susan E. Celniker, Benjamin W. Booth, Ken Wan
Publikováno v:
Genome research. 25(11)
Alternative splicing is regulated by RNA binding proteins (RBPs) that recognize pre-mRNA sequence elements and activate or repress adjacent exons. Here, we used RNA interference and RNA-seq to identify splicing events regulated by 56 Drosophila prote
Autor:
Peter H. Sudmant, Matthew Boitano, John Huddleston, John A. Stamatoyannopoulos, Richard Sandstrom, Fereydoun Hormozdiari, Francesca Antonacci, Jane M. Landolin, Urvashi Surti, Evan E. Eichler, Megan Y. Dennis, Mark Chaisson, Michael W. Hunkapiller, Maika Malig, Jonas Korlach
Publikováno v:
Nature, vol 517, iss 7536
Chaisson, MJP; Huddleston, J; Dennis, MY; Sudmant, PH; Malig, M; Hormozdiari, F; et al.(2015). Resolving the complexity of the human genome using single-molecule sequencing. Nature, 517(7536), 608-611. doi: 10.1038/nature13907. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/78k994t1
Chaisson, MJP; Huddleston, J; Dennis, MY; Sudmant, PH; Malig, M; Hormozdiari, F; et al.(2015). Resolving the complexity of the human genome using single-molecule sequencing. Nature, 517(7536), 608-611. doi: 10.1038/nature13907. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/78k994t1
© 2015 Macmillan Publishers Limited. All rights reserved. The human genome is arguably the most complete mammalian reference assembly, yet more than 160 euchromatic gaps remain and aspects of its structural variation remain poorly understood ten yea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f272c396b0aa0cf8a9b1f532a25d5d3b
https://escholarship.org/uc/item/78k994t1
https://escholarship.org/uc/item/78k994t1
Autor:
Adam M. Phillippy, Sergey Koren, Jane M. Landolin, James P Drake, Chen-Shan Chin, Konstantin Berlin
We report reference-grade de novo assemblies of four model organisms and the human genome from single-molecule, real-time (SMRT) sequencing. Long-read SMRT sequencing is routinely used to finish microbial genomes, but the available assembly methods h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e9c232ea0e3dc9885928d29e93980a