Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jane M. Lalli"'
Publikováno v:
Circulation Research. 80:506-513
Abstract Phospholamban (PLB) is a protein associated with the Ca 2+ -ATPase of the sarcoplasmic reticulum (SR) in cardiac, slow-twitch skeletal, and smooth muscle. PLB inhibits the SR Ca 2+ -ATPase in cardiac muscle; this inhibition is relieved on ph
Publikováno v:
Journal of molecular and cellular cardiology. 33(2)
Cardiac-specific expression of an activated calcineurin protein in the hearts of transgenic (CLN) mice produces a profound hypertrophy that rapidly progresses to heart failure. While calcineurin is regulated by Ca2+, the potential effects of calcineu
Publikováno v:
Journal of molecular and cellular cardiology. 32(8)
Cardiac hypertrophy is associated with specific alterations in myocardial gene expression; however, the exact mechanisms responsible for altered gene expression are poorly defined. The goal of this study was to investigate whether signaling kinases t