Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jane M. Deeley"'
Autor:
Jane M. Deeley, Joseph A. Hankin, Michael G. Friedrich, Robert C. Murphy, Roger J.W. Truscott, Todd W. Mitchell, Stephen J. Blanksby
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 9, Pp 2753-2760 (2010)
The formation of an internal barrier to the diffusion of small molecules in the lens during middle age is hypothesized to be a key event in the development of age-related nuclear (ARN) cataract. Changes in membrane lipids with age may be responsible.
Externí odkaz:
https://doaj.org/article/0e13eedb79194df08944aa0210cb4171
Autor:
Jessica R Hughes, Stephen J. Blanksby, Todd W. Mitchell, Jane M. Deeley, Shane R. Ellis, Roger J.W. Truscott, Friedrich Leisch
Publikováno v:
Clinical & Experimental Ophthalmology. 39:79-90
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebbeae7746a66144322b20a8eb879d1e
https://doi.org/10.1111/j.1442-9071.2011.02704.x
https://doi.org/10.1111/j.1442-9071.2011.02704.x
Autor:
Roger J.W. Truscott, Jane M. Deeley, Todd W. Mitchell, Xiangjia Zhu, Shane R. Ellis, Stephen J. Blanksbya, R. Graham Cooks, Marc in het Panhuis, Chunping Wu
Publikováno v:
Journal of the American Society for Mass Spectrometry. 21:2095-2104
The lipid composition of the human lens is distinct from most other tissues in that it is high in dihydrosphingomyelin and the most abundant glycerophospholipids in the lens are unusual 1-O-alkyl-ether linked phosphatidylethanolamines and phosphatidy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d441559b6e26d5ded14ea42f51d9c5a
https://doi.org/10.1016/j.jasms.2010.09.003
https://doi.org/10.1016/j.jasms.2010.09.003
Autor:
Joseph A. Hankin, Robert C. Murphy, Jane M. Deeley, Roger J.W. Truscott, Todd W. Mitchell, Stephen J. Blanksby, Michael G. Friedrich
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 9, Pp 2753-2760 (2010)
The formation of an internal barrier to the diffusion of small molecules in the lens during middle age is hypothesized to be a key event in the development of age-related nuclear (ARN) cataract. Changes in membrane lipids with age may be responsible.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a24bbe78484faf624cb1259f74cd3f61
http://www.sciencedirect.com/science/article/pii/S0022227520423053
http://www.sciencedirect.com/science/article/pii/S0022227520423053
Autor:
Stephen J. Blanksby, Michael C. Thomas, David G. Harman, Todd W. Mitchell, Robert C. Murphy, Jane M. Deeley
Publikováno v:
Analytical Chemistry. 79:5013-5022
The position(s) of carbon-carbon double bonds within lipids can dramatically affect their structure and reactivity and thus has a direct bearing on biological function. Commonly employed mass spectrometric approaches to the characterization of comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5a10494698da7bae01b9440b3cabb3
https://doi.org/10.1021/ac0702185
https://doi.org/10.1021/ac0702185
Autor:
Friedrich Leisch, Jessica R Hughes, Shane R. Ellis, Todd W. Mitchell, Stephen J. Blanksby, Roger J.W. Truscott, Jane M. Deeley
The human lens nucleus is formed in utero, and from birth onwards, there appears to be no significant turnover of intracellular proteins or membrane components. Since, in adults, this region also lacks active enzymes, it offers the opportunity to exa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37de14b90477fa82ee4069e9249392cd
https://europepmc.org/articles/PMC3682067/
https://europepmc.org/articles/PMC3682067/
Publikováno v:
Analytical chemistry. 81(5)
Previous studies have shown that the human lens contains glycerophospholipids with ether linkages. These lipids differ from conventional glycerophospholipids in that the sn-1 substituent is attached to the glycerol backbone via an 1-O-alkyl or an 1-O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e05ce648334b2ce59229e68142f48b7
https://pubmed.ncbi.nlm.nih.gov/19186979
https://pubmed.ncbi.nlm.nih.gov/19186979
Autor:
Stephen J. Blanksby, Todd W. Mitchell, John Korth, Jessica R. Nealon, Xiaojia Eric Wei, Roger J.W. Truscott, Jane M. Deeley
Publikováno v:
Biochimica et biophysica acta. 1781(6-7)
Electrospray ionisation tandem mass spectrometry has allowed the unambiguous identification and quantification of individual lens phospholipids in human and six animal models. Using this approach ca. 100 unique phospholipids have been characterised.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5533beeb7ab2438f5720796252fb1029
https://pubmed.ncbi.nlm.nih.gov/18474264
https://pubmed.ncbi.nlm.nih.gov/18474264