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Akademický článek

Novel approaches for long-term lung transplant survival

Autor: Cynthia L. Miller, Jane M. O, James S. Allan, Joren C. Madsen

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Allograft failure remains a major barrier in the field of lung transplantation and results primarily from acute and chronic rejection. To date, standard-of-care immunosuppressive regimens have proven unsuccessful in achieving acceptable long-term gra

Externí odkaz: https://doaj.org/article/710e0f4cf3ad45d185ee015eda6b49aa

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Akademický článek

A Mixed-chimerism Protocol Utilizing Thymoglobulin and Belatacept Did Not Induce Lung Allograft Tolerance, Despite Previous Success in Renal Allotransplantation

Autor: Wiebke Sommer, MD, Jane M. O, MD, Kurt B. Pruner, BSc, Abbas Dehnadi, DVM, Kyu Ha Huh, MD, Kortney A. Robinson, MD, Isabel Hanekamp, PhD, Ivy Rosales, MD, Alison S. Bean, BSc, Josh Paster, BSc, Tetsu Oura, MD, Rex Neal Smith, MD, Robert Colvin, MD, Gilles Benichou, PhD, Tatsuo Kawai, MD, Joren C. Madsen, MD, DPhil, James S. Allan, MD

Publikováno v: Transplantation Direct, Vol 7, Iss 6, p e705 (2021)

Background. In kidney transplantation, long-term allograft acceptance in cynomolgus macaques was achieved using a mixed-chimerism protocol based on the clinically available reagents, rabbit anti-thymocyte globulin (ATG), and belatacept. Here, we have

Externí odkaz: https://doaj.org/article/bd669e56c0064385a41b8fca2c2ee16e

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