Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Jane Loftus"'
Autor:
Aristides K. Maniatis, Mauri Carakushansky, Sonya Galcheva, Gnanagurudasan Prakasam, Larry A. Fox, Adriana Dankovcikova, Jane Loftus, Andrew A. Palladino, Maria de los Angeles Resa, Carrie Turich Taylor, Mehul T. Dattani, Jan Lebl
Publikováno v:
Therapeutic Advances in Endocrinology and Metabolism, Vol 15 (2024)
• For children with growth hormone deficiency, once-weekly somatrogon injections were less of a burden than once-daily somatropin injections. • The safety of weekly somatrogon was similar to that of daily somatropin . • Compared with daily soma
Externí odkaz:
https://doaj.org/article/5b79e948eadb4ee5b608de45c4e95871
Autor:
Roy Gomez, Roger Lamoureux, Diane M. Turner-Bowker, Jane Loftus, Mohamad Maghnie, Bradley S. Miller, Michel Polak, Andrew Yaworsky
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionThe standard of care for pediatric growth hormone deficiency (pGHD) is once-daily recombinant human growth hormone (rhGH). Somatrogon, a long-acting rhGH, requires less frequent, once-weekly, dosing. We describe physicians’ preference f
Externí odkaz:
https://doaj.org/article/c25dfd24fe344bf4bef41ceea8b433db
Autor:
Jane Loftus, Jen Wogen, David Oliveri, Darrin Benjumea, Priti Jhingran, Yong Chen, Jose Alvir, Elena Rivero-Sanz, Jack C. Kowalik, Michael P. Wajnrajch
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundChildren with growth hormone deficiency (GHD) are treated with daily somatropin injections; however, poor treatment persistence and adherence have been recognized previously and have been shown to negatively impact growth outcomes. A recent
Externí odkaz:
https://doaj.org/article/b0c33c2a28494ac79452fab4bd05851c
Autor:
Jane Loftus, Andrew Yaworsky, Diane Turner-Bowker, Andrew Palladino, Roger Lamoureux, Emily Love, Andreas Pleil
Publikováno v:
Patient Experience Journal, Vol 9, Iss 2 (2022)
Treatments outside of a clinical setting may be managed independently by the pediatric patient, independently by a caregiver, or by the patient and caregiver together. Best practices for pediatric clinical outcome assessment (COA) recommend patient-r
Externí odkaz:
https://doaj.org/article/66bff3494d504723ad2e2a3b00d94c60
Autor:
Jane Loftus, Andrew Yaworsky, Carl L Roland, Diane Turner-Bowker, Megan McLafferty, Sylvia Su, Roger E Lamoureux
Publikováno v:
PLoS ONE, Vol 17, Iss 11, p e0278293 (2022)
BackgroundDaily injections of recombinant human growth hormone are the standard of care to treat growth failure due to pediatric growth hormone deficiency (GHD). While effective, daily injections are burdensome and can compromise adherence. In recent
Externí odkaz:
https://doaj.org/article/49c3dccce5c54f34af8051c9443f1e9a
Autor:
Jane Loftus, Bradley S. Miller, Craig S. Parzynski, Jose Alvir, Yong Chen, Priti Jhingran, Anu Gupta, Mitch DeKoven, Victoria Divino, Jenny Tse, Jing He, Michael Wajnrajch
Publikováno v:
Endocrine Practice. 28:565-571
Recombinant human growth hormone (somatropin) is recommended for children with growth hormone deficiency (GHD) to normalize adult height. Prior research has indicated an association between adherence to somatropin and height velocity. Further researc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58d50dbaea5e8f6516a1153191967f9d
https://doi.org/10.1016/j.eprac.2022.02.013
https://doi.org/10.1016/j.eprac.2022.02.013
Autor:
Jane Loftus, Jen Wogen, David Oliveri, Darrin Benjumea, Priti Jhingran, Yong Chen, Jose Alvir, Elena Rivero Sanz, Jack Charles Kowalik
Publikováno v:
Journal of the Endocrine Society. 6:A605-A606
Background Suboptimal adherence to, and persistence with, daily somatropin therapy to treat children with growth hormone deficiency (GHD) has been documented previously, and has also been shown to have negative effects on the growth response. Objecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b98435cfb73923eebf01b993378a8c26
https://doi.org/10.1210/jendso/bvac150.1256
https://doi.org/10.1210/jendso/bvac150.1256
Autor:
Roy Gomez, Jane Loftus, Andrew Yaworsky, Roger Lamoureux, Michel Polak, Mohamad Maghnie, Bradley S Miller
Publikováno v:
Journal of the Endocrine Society. 6:A628-A629
Background Somatrogon is a long-acting recombinant human growth hormone (hGH) currently being developed as a once-weekly subcutaneous injectable treatment for pediatric patients with growth hormone deficiency (GHD). A recent global Phase 3 study comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8a0a31b1476af215b0a70358a05466e
https://doi.org/10.1210/jendso/bvac150.1303
https://doi.org/10.1210/jendso/bvac150.1303
Autor:
Jane Loftus, Yong Chen, Anu Gupta, Michael P. Wajnrajch, Jose Ma. J. Alvir, Lawrence A. Silverman, Priti Jhingran, Mahesh Kumar, Sapna Prasad
Publikováno v:
Current medical research and opinion. 38(6)
The objective of this retrospective cohort study was to describe the adherence and discontinuation patterns of somatropin over 3 years among children with pGHD insured by Medicaid across the United States.Eligible children were aged ≥3 and16 years
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::554636dfb4b1cf25a17bf081936f28b2
https://pubmed.ncbi.nlm.nih.gov/35477409
https://pubmed.ncbi.nlm.nih.gov/35477409
Autor:
Hillary Gross, Andreas M. Pleil, Andrew Palladino, Diane M. Turner-Bowker, A. Yaworsky, Hal Westhead, Jane Loftus, Michelle McNamara
Publikováno v:
Patient preference and adherence
Michelle McNamara,1 Diane M Turner-Bowker,2 Hal Westhead,3 Andrew Yaworsky,2 Andrew Palladino,4 Hillary Gross,1 Andy Pleil,5 Jane Loftus6 1Adelphi Research, Doylestown, PA, USA; 2Adelphi Values, Boston, MA, USA; 3Adelphi Research, Manchester, UK; 4Pf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4979a9fcfa137993c5b292be58436ef9
https://doi.org/10.2147/ppa.s239196
https://doi.org/10.2147/ppa.s239196