Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jane Linnell"'
Publikováno v:
Journal of Biological Chemistry. 276:23986-23991
The interaction of soluble forms of the human cation-independent insulin-like growth factor-II/mannose 6-phosphate receptor (IGF-IIR) with IGFs and mannosylated ligands was analyzed in real time. IGF-IIR proteins containing domains 1-15, 10-13, 11-13
Autor:
Irina A. Udalova, Richard Mott, Dominic P. Kwiatkowski, Simon Field, Jiannis Ragoussis, Jane Linnell
Publikováno v:
Nucleic acids research. 32(4)
We present a general high-throughput approach to accurately quantify DNA-protein interactions, which can facilitate the identification of functional genetic polymorphisms. The method tested here on two structurally distinct transcription factors (TFs
Autor:
E. Yvonne Jones, Karl Harlos, Jane Linnell, Robert Esnouf, James Brown, Margaret A. Jones, A. Bassim Hassan
Publikováno v:
The EMBO journal. 21(5)
Insulin-like growth factor II receptor (IGF2R) is a multifunctional cell surface receptor implicated in tumour suppression. Its growth inhibitory activity has been associated with an ability to bind IGF-II. IGF2R contains 15 homologous extracellular