Hippocampal shape is associated with memory deficits in temporal lobe epilepsy

Autor: Jane L. Burdett, John S. Duncan, Jane de Tisi, Matthias J. Koepp, Marian Galovic, Gavin P. Winston, Maria Thom, Sallie Baxendale, Lorenzo Caciagli, Tjardo S. Postma, Sjoerd B. Vos, Meneka K. Sidhu, Irene Cano-López, Claire Cury, Pamela J. Thompson

Publikováno v: Annals of Neurology
Annals of Neurology, Wiley, 2020, 88 (1), pp.170-182. ⟨10.1002/ana.25762⟩
Annals of Neurology, 2020, 88 (1), pp.170-182. ⟨10.1002/ana.25762⟩

International audience; OBJECTIVES:Cognitive problems, especially disturbances in episodic memory, and hippocampal sclerosis are common in temporal lobe epilepsy (TLE) but little is known about the relationship of hippocampal morphology with memory.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48bc7c2110129d985cd6f7e9435ba10f
https://www.hal.inserm.fr/inserm-02611665v2/file/document

The impact of brain‐derived neurotrophic factor Val66Met polymorphism on cognition and functional brain networks in patients with intractable partial epilepsy

Autor: Marina Perona, Jane L. Burdett, Alexandra Foulkes, Silvia B. Bonelli, Meneka K. Sidhu, Jason Stretton, John S. Duncan, E. Williams, Maria Thom, Britta Wandschneider, Jane de Tisi, Mar Matarin, Pamela J. Thompson

Introduction Medial temporal lobe epilepsy (mTLE) is the most common refractory focal epilepsy in adults. Around 30%-40% of patients have prominent memory impairment and experience significant postoperative memory and language decline after surgical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac89759a1532a43aec4bf9a93e37913
https://europepmc.org/articles/PMC6488925/

The value of repeat neuroimaging for epilepsy at a tertiary referral centre: 16 years of experience☆

Autor: Jane L. Burdett, Brian E. Kendell, E. Williams, John S. Duncan, Gavin P. Winston, Philippa A. Bartlett, Caroline Micallef

Publikováno v: Epilepsy Research

Highlights • 20–30% of patients with refractory focal epilepsy have normal MRI scans. • We evaluated the role of repeated MRI with better technology in detecting pathology. • 804 patients underwent MRI at 1.5T and subsequently at 3T with supe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::884a7028a1873fc68735abb92dfbeacf
http://europepmc.org/articles/PMC3888924

Increased sensitivity to pathological brain changes using co-registration of magnetic resonance imaging scans

Autor: D. Flügel, John M. Stevens, Louis Lemieux, E. Williams, John S. Duncan, Jane L. Burdett

Publikováno v: Acta radiologica (Stockholm, Sweden : 1987). 47(10)

Purpose: To compare automatic software-based co-registration of serial magnetic resonance imaging (MRI) scans with conventional visual comparison, by expert neuroradiologists. Material and Methods: Sixty-four patients who were referred to our epileps

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbddce3004ba7903f356a7e3a3fd3468
https://pubmed.ncbi.nlm.nih.gov/17135010

KETO–ENOL TAUTOMERISM IN β-DICARBONYLS STUDIED BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY: II. SOLVENT EFFECTS ON PROTON CHEMICAL SHIFTS AND ON EQUILIBRIUM CONSTANTS

Autor: Jane L. Burdett, Max T. Rogers

Publikováno v: Canadian Journal of Chemistry. 43:1516-1526

The effect of various solvents on the proton chemical shifts of a number of acyclic β-di-ketones and β-ketoesters has been observed by nuclear magnetic resonance spectroscopy. These shifts are discussed in terms of the dissociation of intramolecula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::35b6c9b0f22341d7e8a2b7685e80c71b
https://doi.org/10.1139/v65-202