Hierarchy of risk of childhood-onset rheumatoid arthritis conferred by HLA-DRB1 alleles encoding the shared epitope

Autor: Traci Leong, Sheila T. Angeles-Han, Andrew Zeft, Jane L. Park, Sampath Prahalad, Ann M. Reed, John F. Bohnsack, Milton R. Brown, Larry B. Vogler, Christine Kennedy, Lori A. Ponder, Jennifer Prozonic, Yunxuan Jiang, Karen N. Conneely, Susan D. Thompson, Marilynn Punaro, Carol A. Wallace, Elizabeth D. Mellins, Carol Wise, David N. Glass

Publikováno v: Arthritis & Rheumatism. 64:925-930

Rheumatoid arthritis (RA), which is estimated to affect ~1% of the adult population, is the most common form of inflammatory arthritis in the world. A substantial majority of individuals with RA have rheumatoid factor (RF) and/or anti-citrullinated p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d5a787f5dc64d56d5a6ef6eceaf96ab7
https://doi.org/10.1002/art.33376

Monocytes are resistant to apoptosis in systemic juvenile idiopathic arthritis

Autor: Yue Sun, Elizabeth D. Mellins, Tzielan Lee, Ann B. Begovich, Claudia Macaubas, Jane L. Park, Sheng Yung Chang, Shivani Srivastava, Heather C. Alexander, Chetan Deshpande

Publikováno v: Clinical Immunology. 136:257-268

We investigated whether circulating monocytes from patients with systemic juvenile idiopathic arthritis (SJIA) are resistant to apoptosis and which apoptotic pathway(s) may mediate this resistance. A microarray analysis of peripheral blood mononuclea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fadaf43790173ebbe9ee8e18ef38ae1
https://doi.org/10.1016/j.clim.2010.04.003

Classification, presentation, and initial treatment of Wegener's granulomatosis in childhood

Autor: Raphael Hirsh, Aisha Ali, Susanne M. Benseler, Robert P. Sundel, Karen Watanabe Duffy, Elizabeth A. Shaw, Jane L. Park, Ciarán M. Duffy, Rosie Scuccimarri, Peter Chira, Laura E. Schanberg, Melissa M. Hazen, Christi J. Inman, Deborah Bork, Amy Woodward, Suzanne E. Ramsey, Elizabeth B. Brooks, Yukiko Kimura, Dawn M. Wahezi, Jennifer Frankovich, Kristin Houghton, Andrew Zeft, Dana Gerstbacher, Robert C. Fuhlbrigge, James N. Jarvis, Susan H. Ballinger, Candido Batres, Suzanne C. Li, Bracha Shaham, Anne M. Stevens, Jennifer Turner, Deborah McCurdy, Esi Morgan DeWitt, Ana Cabrera, Margalit Rosenkrank, Reuven Bromberg, Lisa Imundo, John Bonsack, Andrea Hudgins, David A. Cabral, A. Grom, Kenneth N. Schikler, Lorien Nassi, Sarah Ringold, Bianca A. Lang, Daniel J. Kingsbury, Aleasha Warner, Rhonda Wilder, Michael Henrickson, Fatma Dedeoglu, Gaëlle Chédeville, Troy R. Torgerson, Suzanne L. Bowyer, Mary Beth F. Son, Marilynn Punaro, Daniel Kietz, Diane E. Brown, Imelda Balboni, Helen Emery, Sarah Halford, Michal Cidon, Marisa S. Klein-Gitelman, Tzielan Lee, Steven J. Spalding, Anne Eberhard, Anne Johnson, Leslie Abramson, Adrienne Michels, Kristin Hayward, Paul Rosen, Michele Gibbon, Thomas G. Mason, Andreas Reiff, Peter N. Malleson, Lauren M. Pachman, Deborah M. Levy, Victor Espinosa, Kathleen A. Haines, Christy Sandborg, Carol A. Wallace, Adam M. Huber, Hermine I. Brunner, Lori B. Tucker, Steven J. Song, Philip J. Hashkes, S Prahalad, Stacy P. Ardoin, Thomas A. Griffin, Elizabeth Stringer, Virginia Pascual, Gloria C. Higgins, América G. Uribe, Jennifer Wargula, Stuart E. Turvey, Kathleen M. O'Neil, Jaime Guzman, Andrew H. Eichenfield, Thaschawee Arkachaisri, Norman T. Ilowite, Sarah Campillo, Ann M. Reed, Aimee O. Hersh, J Weiss, Susan Kim, Barry L. Myones, Mary Lesko, Emily von Scheven, Joyce J. Hsu, Nora G. Singer, Eyal Muscal, Thomas Klausmeier, Daniel J. Lovell, Egla Rabinovich, Kathryn S. Torok, Ross E. Petty

Publikováno v: Arthritis & Rheumatism. 60:3413-3424

Objective To compare the criteria for Wegener's granulomatosis (WG) of the American College of Rheumatology (ACR) with those of the European League Against Rheumatism/Pediatric Rheumatology European Society (EULAR/PRES) in a cohort of children with W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f459066f057842c36e1177540078595f
https://doi.org/10.1002/art.24876

Susceptibility to childhood onset rheumatoid arthritis: investigation of a weighted genetic risk score that integrates cumulative effects of five genetic risk variants

Autor: Ann M. Reed, Lori A. Ponder, Christine Kennedy, Sampath Prahalad, John F. Bohnsack, Susan D. Thompson, Jennifer Prozonic, Carol Wise, David N. Glass, Jane L. Park, Milton R. Brown, Elizabeth D. Mellins, Marilynn Punaro, Larry B. Vogler, Michael E. Zwick, Sheila T. Angeles-Han, Carol A. Wallace, David J. Cutler

Publikováno v: Pediatric Rheumatology Online Journal, Vol 10, Iss Suppl 1, p A116 (2012)
Pediatric Rheumatology Online Journal

Susceptibility to childhood onset rheumatoid arthritis: investigation of a weighted genetic risk score that integrates cumulative effects of five genetic risk variants Sampath Prahalad, Milton Brown, Susan D Thompson, Michael Zwick, David Cutler, Lor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::742516faf6a54b895bc42f125c8a49ac
https://doi.org/10.1186/1546-0096-10-s1-a116

Alternative activation in systemic juvenile idiopathic arthritis monocytes

Autor: Jane L. Park, Heather C. Alexander, Sheng Yung Chang, Chetan Deshpande, Khoa D. Nguyen, Tzielan Lee, Julia Buckingham, Elizabeth D. Mellins, Richard Z. Lin, Kuang Hung Pan, Carolyn M. Phillips, Andreas V. Hadjinicolaou, Elizabeth Wong, Yue Sun, Ariana Peck, Erin M. Augustine, Chih Jian Lih, Claudia Macaubas, Ann B. Begovich

Publikováno v: Clinical immunology (Orlando, Fla.). 142(3)

Systemic juvenile idiopathic arthritis (SJIA) is a chronic autoinflammatory condition. The association with macrophage activation syndrome, and the therapeutic efficacy of inhibiting monocyte-derived cytokines, has implicated these cells in SJIA path

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c343432a61e97125a34eba01bebf8e5
https://pubmed.ncbi.nlm.nih.gov/22281427