A parasite DNA binding protein with potential to influence disease susceptibility acts as an analogue of mammalian HMGA transcription factors.

Autor: Zeeshan Durrani, Jane Kinnaird, Chew Weng Cheng, Francis Brühlmann, Paul Capewell, Andrew Jackson, Stephen Larcombe, Philipp Olias, William Weir, Brian Shiels

Publikováno v: PLoS ONE, Vol 18, Iss 6, p e0286526 (2023)

Intracellular pathogens construct their environmental niche, and influence disease susceptibility, by deploying factors that manipulate infected host cell gene expression. Theileria annulata is an important tick-borne parasite of cattle that causes t

Externí odkaz: https://doaj.org/article/4301a03bffa447bbac359fbb8f6b23b4

Identification of candidate transmission-blocking antigen genes in Theileria annulata and related vector-borne apicomplexan parasites

Autor: Laetitia Lempereur, Stephen D. Larcombe, Zeeshan Durrani, Tulin Karagenc, Huseyin Bilgin Bilgic, Serkan Bakirci, Selin Hacilarlioglu, Jane Kinnaird, Joanne Thompson, William Weir, Brian Shiels

Publikováno v: BMC Genomics, Vol 18, Iss 1, Pp 1-14 (2017)

Abstract Background Vector-borne apicomplexan parasites are a major cause of mortality and morbidity to humans and livestock globally. The most important disease syndromes caused by these parasites are malaria, babesiosis and theileriosis. Strategies

Externí odkaz: https://doaj.org/article/0a6fea09baea4e92a5fe8ce4566eebce

Genetic Diversity and Population Structure of Theileria annulata in Oman.

Autor: Salama Al-Hamidhi, Mohammed H Tageldin, William Weir, Amira Al-Fahdi, Eugene H Johnson, Patrick Bobade, Badar Alqamashoui, Albano Beja-Pereira, Joanne Thompson, Jane Kinnaird, Brian Shiels, Andy Tait, Hamza Babiker

Publikováno v: PLoS ONE, Vol 10, Iss 10, p e0139581 (2015)

BackgroundTheileriosis, caused by a number of species within the genus Theileria, is a common disease of livestock in Oman. It is a major constraint to the development of the livestock industry due to a high rate of morbidity and mortality in both ca

Externí odkaz: https://doaj.org/article/00ef6e7884ab400cba1d293695975050

Identification of candidate transmission-blocking antigen genes in Theileria annulata and related vector-borne apicomplexan parasites

Autor: William Weir, Selin Hacilarlioglu, Zeeshan Durrani, Jane Kinnaird, Stephen D. Larcombe, Serkan Bakirci, Laetitia Lempereur, Hüseyin Bilgin Bilgiç, Joanne Thompson, Brian Shiels, Tülin Karagenç

Publikováno v: BMC Genomics, Vol 18, Iss 1, Pp 1-14 (2017)
Lempereur, L, Larcombe, S D, Durrani, Z, Karagenc, T, Bilgic, H, Bakirci, S, Hacilarlioglu, S, Kinnaird, J, Thompson, J, Weir, W & Shiels, B 2017, ' Identification of candidate transmission-blocking antigen genes in Theileria annulata and related vector-borne apicomplexan parasites ', BMC Genomics, vol. 18 . https://doi.org/10.1186/s12864-017-3788-1
BMC Genomics
BMC GENOMICS

Background Vector-borne apicomplexan parasites are a major cause of mortality and morbidity to humans and livestock globally. The most important disease syndromes caused by these parasites are malaria, babesiosis and theileriosis. Strategies for cont

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf270ff225dbb30a8c6de573354a0920
http://link.springer.com/article/10.1186/s12864-017-3788-1

Characterisation of infection associated microRNA and protein cargo in extracellular vesicles of Theileria annulata infected leukocytes

Autor: Jane Kinnaird, Eileen Devaney, Victoria Gillan, Brian Shiels, Kirsty Maitland, Deborah M. Simpson

Publikováno v: Cellular Microbiology

The protozoan parasites Theileria annulata and Theileria parva are unique amongst intracellular eukaryotic pathogens as they induce a transformation‐like phenotype in their bovine host cell. T. annulata causes tropical theileriosis, which is freque

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8760a2b2c887405126bbc852fc83f485
https://pubmed.ncbi.nlm.nih.gov/30370674