Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Jane K Cleal"'
Autor:
Jennifer E Pearson-Farr, Gabrielle Wheway, Maaike S A Jongen, Patricia Goggin, Rohan M Lewis, Ying Cheong, Jane K Cleal
Publikováno v:
Reproduction and Fertility, Vol 3, Iss 3, Pp 162-172 (2022)
Endometrial glands are essential for fertility, consisting of ciliated and secretory cells that facilitate a suitable uterine environment for embryo implantation. This study sought to determine whether an endometrial gland-specific transcriptome and
Externí odkaz:
https://doaj.org/article/3de3c65fc602463b881e38ac265d6268
Autor:
Brogan Ashley, Claire Simner, Antigoni Manousopoulou, Carl Jenkinson, Felicity Hey, Jennifer M Frost, Faisal I Rezwan, Cory H White, Emma M Lofthouse, Emily Hyde, Laura DF Cooke, Sheila Barton, Pamela Mahon, Elizabeth M Curtis, Rebecca J Moon, Sarah R Crozier, Hazel M Inskip, Keith M Godfrey, John W Holloway, Cyrus Cooper, Kerry S Jones, Rohan M Lewis, Martin Hewison, Spiros DD Garbis, Miguel R Branco, Nicholas C Harvey, Jane K Cleal
Publikováno v:
eLife, Vol 11 (2022)
Pregnancy 25-hydroxyvitamin D [25(OH)D] concentrations are associated with maternal and fetal health outcomes. Using physiological human placental perfusion and villous explants, we investigate the role of the placenta in regulating the relationships
Externí odkaz:
https://doaj.org/article/1a91c1a9eb944011801afd9ea0ec61b3
Autor:
Pricilla E Day, Georgia Ntani, Sarah R Crozier, Pam A Mahon, Hazel M Inskip, Cyrus Cooper, Nicholas C Harvey, Keith M Godfrey, Mark A Hanson, Rohan M Lewis, Jane K Cleal
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143653 (2015)
IntroductionMaternal environment and lifestyle factors may modify placental function to match the mother's capacity to support the demands of fetal growth. Much remains to be understood about maternal influences on placental metabolic and amino acid
Externí odkaz:
https://doaj.org/article/7fb9427702274b929bd4491f9fac7c81
Autor:
Kirsten R Poore, Lisa J Hollis, Robert J S Murray, Anna Warlow, Andrew Brewin, Laurence Fulford, Jane K Cleal, Karen A Lillycrop, Graham C Burdge, Mark A Hanson, Lucy R Green
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90994 (2014)
Epidemiological and experimental studies suggest early nutrition has long-term effects on susceptibility to obesity, cardiovascular and metabolic diseases. Small and large animal models confirm the influence of different windows of sensitivity, from
Externí odkaz:
https://doaj.org/article/de02fa258a244a46a646d6378a239ebb
Autor:
Jennifer M. Frost, Samuele M. Amante, Hiroaki Okae, Eleri M. Jones, Brogan Ashley, Rohan M. Lewis, Jane K. Cleal, Matthew P. Caley, Takahiro Arima, Tania Maffucci, Miguel R. Branco
Publikováno v:
Nature Structural & Molecular Biology. 30:527-538
The placenta is a fast-evolving organ with large morphological and histological differences across eutherians, but the genetic changes driving placental evolution have not been fully elucidated. Transposable elements, through their capacity to quickl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb795c7139991854881f11795581ec0d
https://doi.org/10.1038/s41594-023-00960-6
https://doi.org/10.1038/s41594-023-00960-6
Autor:
Jennifer E Pearson-Farr, Gabrielle Wheway, Maaike S A Jongen, Patricia Goggin, Rohan M Lewis, Ying Cheong, Jane K Cleal
Publikováno v:
Reproduction and Fertility. 3:162-172
Endometrial glands are essential for fertility, consisting of ciliated and secretory cells that facilitate a suitable uterine environment for embryo implantation. This study sought to determine whether an endometrial gland-specific transcriptome and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f803b8d363e9b4a07089b87a33908b6
https://doi.org/10.1530/raf-22-0002
https://doi.org/10.1530/raf-22-0002
Autor:
Jane K. Cleal, David A. Tumbarello, Nicholas C. Harvey, Laura D.F. Cooke, Rohan M. Lewis, Jaswinder K. Sethi
Publikováno v:
Placenta. 113:67-73
Endocytosis is an essential mechanism for cellular uptake in many human tissues. A range of endocytic mechanisms occur including clathrin-dependent and -independent mechanisms. However, the role of endocytosis in the placenta and the spatial localisa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a254c1da5e9d516b1c6ed53c34813c
https://doi.org/10.1016/j.placenta.2021.04.014
https://doi.org/10.1016/j.placenta.2021.04.014
Autor:
Rebecca J Moon, Laura D F Cooke, Stefania D’Angelo, Elizabeth M Curtis, Philip Titcombe, Justin H Davies, Keith M Godfrey, Jane K Cleal, Rohan M Lewis, Cyrus Cooper, Nicholas C Harvey
Publikováno v:
J Clin Endocrinol Metab
Context Single nucleotide polymorphisms (SNPs) in vitamin D metabolism pathway genes are associated with circulating 25-hydroxyvitamin D (25(OH)D) in adults. Less is known about the relationships between mother and offspring SNPs and umbilical cord b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4bdef363809b8f646043dfed6a1b1fe
https://eprints.soton.ac.uk/457055/
https://eprints.soton.ac.uk/457055/
Autor:
David A. Johnston, Stanimir A. Tashev, Shelley Harris, Patricia Goggin, Maaike Sa. Jongen, Emma M. Lofthouse, Jennifer E. Pearson-Farr, Anton Page, Eleni Palaiologou, Rohan M. Lewis, Kate Sh. Matthews, David S. Chatelet, Jane K. Cleal
Publikováno v:
Placenta
Introduction Pericytes are a common feature in the placental microvasculature but their roles are not well understood. Pericytes may provide physical or endocrine support for endothelium and in some tissues mediate vasoconstriction. Methods This stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d10e692ad7a0b4ae144b296a3e1fd3b
http://europepmc.org/articles/PMC7921774
http://europepmc.org/articles/PMC7921774
Autor:
Emily Hyde, Sheila J. Barton, Miguel R. Branco, Cory H. White, Spiros D Garbis, Claire Simner, Faisal I. Rezwan, Nicholas C. Harvey, P A Mahon, Rebecca J Moon, Felicity Hey, Kerry S Jones, Martin Hewison, Cyrus Cooper, John W. Holloway, Antigoni Manousopoulou, Elizabeth M Curtis, Carl Jenkinson, Hazel Inskip, Sarah Crozier, Rohan M. Lewis, Brogan Ashley, Emma M. Lofthouse, Laura Cooke, Jennifer M. Frost, Jane K. Cleal, Keith M. Godfrey
Publikováno v:
BiorXiv
bioRxiv
bioRxiv
Funder: Gerald Kerkut Charitable Trust; FundRef: http://dx.doi.org/10.13039/100012166
Funder: Rank Prize
Funder: NIHR Clinical Lectureship
Pregnancy 25-hydroxyvitamin D [25(OH)D] concentrations are associated with maternal and fetal he
Funder: Rank Prize
Funder: NIHR Clinical Lectureship
Pregnancy 25-hydroxyvitamin D [25(OH)D] concentrations are associated with maternal and fetal he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96fff767936936a8cd53243f0bfdb106