Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jane Jacques"'
Autor:
James J. Fink, Nathaniel Delaney-Busch, Ryan Dawes, Evanthia Nanou, Christopher Folts, Karthiayani Harikrishnan, Chris Hempel, Hansini Upadhyay, Trinh Nguyen, Himali Shroff, David Stoppel, Steven J. Ryan, Jane Jacques, Jennifer Grooms, Elizabeth Berry-Kravis, Mark F. Bear, Luis A. Williams, David Gerber, Mark Bunnage, Brinley Furey, Graham T. Dempsey
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract Fragile X syndrome (FXS) is a neurodevelopmental disorder caused by hypermethylation of expanded CGG repeats (>200) in the FMR1 gene leading to gene silencing and loss of Fragile X Messenger Ribonucleoprotein (FMRP) expression. FMRP plays im
Externí odkaz:
https://doaj.org/article/4c3520c6a9254e29bb6412e3a3c39efa
Autor:
Gabriel B. Borja, Hongkang Zhang, Benjamin N. Harwood, Jane Jacques, Jennifer Grooms, Romina O. Chantre, Dawei Zhang, Adam Barnett, Christopher A. Werley, Yang Lu, Steven F. Nagle, Owen B. McManus, Graham T. Dempsey
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Optogenetic assays provide a flexible, scalable, and information rich approach to probe compound effects for ion channel drug targets in both heterologous expression systems and associated disease relevant cell types. Despite the potential utility an
Externí odkaz:
https://doaj.org/article/fbccbcbdfa4349c68b6c7eb8e5f3089d
Autor:
He Tian, Hunter C. Davis, J. David Wong-Campos, Pojeong Park, Linlin Z. Fan, Benjamin Gmeiner, Shahinoor Begum, Christopher A. Werley, Gabriel B. Borja, Hansini Upadhyay, Himali Shah, Jane Jacques, Yitong Qi, Vicente Parot, Karl Deisseroth, Adam E. Cohen
Publikováno v:
Nature Methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3616681bfbc25067b06acdf51fbf58cb
https://doi.org/10.1038/s41592-022-01743-5
https://doi.org/10.1038/s41592-022-01743-5
Autor:
Pin W. Liu, Hongkang Zhang, Christopher A. Werley, Monika Pichler, Steve Ryan, Caitlin Lewarch, Jane Jacques, Jennifer Grooms, John Ferrante, Guangde Li, Dawei Zhang, Nate Bremmer, Adam Barnett, Romina Chantre, Amy E. Elder, Adam E. Cohen, Luis A. Williams, Graham T. Dempsey, Owen B. McManus
Chronic pain associated with osteoarthritis (OA) remains an intractable problem with few effective treatment options. New approaches are needed to model the disease biology and to drive discovery of therapeutics. Here, we present anin vitromodel of O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::088799b6f5f999c7b434c1b6a4461ccb
https://doi.org/10.1101/2022.12.12.520139
https://doi.org/10.1101/2022.12.12.520139
Autor:
He Tian, Hunter C. Davis, J. David Wong-Campos, Pojeong Park, Linlin Z. Fan, Benjamin Gmeiner, Shahinoor Begum, Christopher A. Werley, Gabriel B. Borja, Hansini Upadhyay, Himali Shah, Jane Jacques, Yitong Qi, Vicente Parot, Karl Deisseroth, Adam E. Cohen
Publikováno v:
Nature Methods. 20:469-469
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82ccf82eeecac36ae1f3292eea7a48e4
https://doi.org/10.1038/s41592-023-01805-2
https://doi.org/10.1038/s41592-023-01805-2
Autor:
Christopher A. Werley, Pojeong Park, Shahinoor Begum, He Tian, Vicente Parot, Benjamin Gmeiner, Gabriel B. Borja, Hansini Upadhyay, J. David Wong-Campos, Linlin Z. Fan, Yitong Qi, Hunter C. Davis, Himali Shah, Jane Jacques, Karl Deisseroth, Adam E. Cohen
All-optical electrophysiology can be a powerful tool for studying neural dynamics in vivo, as it offers the ability to image and perturb membrane voltage in multiple cells simultaneously. The “Optopatch” constructs combine a red-shifted archaerho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c03b9f65e85f7898879de5f0d01fbe66
https://doi.org/10.1101/2021.11.22.469481
https://doi.org/10.1101/2021.11.22.469481