Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jane I Lin"'
Autor:
Jane I Lin, Naomi C Mitchell, Marina Kalcina, Elly Tchoubrieva, Mary J Stewart, Steven J Marygold, Cherryl D Walker, George Thomas, Sally J Leevers, Richard B Pearson, Leonie M Quinn, Ross D Hannan
Publikováno v:
PLoS Genetics, Vol 7, Iss 12, p e1002408 (2011)
The ribosome is critical for all aspects of cell growth due to its essential role in protein synthesis. Paradoxically, many Ribosomal proteins (Rps) act as tumour suppressors in Drosophila and vertebrates. To examine how reductions in Rps could lead
Externí odkaz:
https://doaj.org/article/fca2638bcbb24c7889f06530e5409653
Publikováno v:
Haematologica, Vol 105, Iss 8 (2020)
Externí odkaz:
https://doaj.org/article/117a92b1ff434ece9a7afd25f5497c80
Publikováno v:
Haematologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8a4191dfa1f08b1040f987a69e79c79
https://doi.org/10.3324/haematol.2020.250969
https://doi.org/10.3324/haematol.2020.250969
Autor:
Juan Nunez-Iglesias, Linda Hii, Julie Chan, Jane I. Lin, Karel Novy, Maheshi Udugama, Benjamin Vinod, Lee H. Wong, Roger J. Daly, Cheng Huang, Hilda A. Pickett, Ralf B. Schittenhelm, Foong Lyn Chan
Publikováno v:
Nucleic Acids Research
AURKB (Aurora Kinase B) is a serine/threonine kinase better known for its role at the mitotic kinetochore during chromosome segregation. Here, we demonstrate that AURKB localizes to the telomeres in mouse embryonic stem cells, where it interacts with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c931b86249278877fe2ece620c56c08
https://pubmed.ncbi.nlm.nih.gov/29040668
https://pubmed.ncbi.nlm.nih.gov/29040668
Publikováno v:
Developmental Cell. 21:896-906
SummaryThe Salvador-Warts-Hippo (SWH) pathway is a complex signaling network that controls both developmental and regenerative tissue growth. Using a genetic screen in Drosophila melanogaster, we identified the sterile 20-like kinase, Tao-1, as an SW
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ddd97812d4b6cbf0ce353278104730d
https://doi.org/10.1016/j.devcel.2011.09.012
https://doi.org/10.1016/j.devcel.2011.09.012
Publikováno v:
BMC Developmental Biology
Background Ecdysone triggers transcriptional changes via the ecdysone receptor (EcR) to coordinate developmental programs of apoptosis, cell cycle and differentiation. Data suggests EcR affects cell cycle gene expression indirectly and here we identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa505f0596bd21f281fadeca405acb83
https://doi.org/10.1186/1471-213x-13-28
https://doi.org/10.1186/1471-213x-13-28
Publikováno v:
Science Signaling. 6
An important regulator of organ size and tumorigenesis is the Hippo pathway. Recent studies have unveiled increasing complexity in regulation of Hippo pathway activity at the level of the oncoprotein Yes-associated protein (YAP). The protein tyrosine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c60779822a3a4c6688d368bdac57a4
https://doi.org/10.1126/scisignal.2003813
https://doi.org/10.1126/scisignal.2003813
Autor:
Mary J. Stewart, Ross D. Hannan, Marina Kalcina, Naomi C Mitchell, Sally J. Leevers, Richard B. Pearson, Jane I Lin, Steven J Marygold, George Thomas, Leonie M. Quinn, Cherryl D. Walker, Elissaveta B Tchoubrieva
Publikováno v:
PLoS Genetics, Vol 7, Iss 12, p e1002408 (2011)
PLoS Genetics
PLoS Genetics
The ribosome is critical for all aspects of cell growth due to its essential role in protein synthesis. Paradoxically, many Ribosomal proteins (Rps) act as tumour suppressors in Drosophila and vertebrates. To examine how reductions in Rps could lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29f0eb133fa64b2c6e8b549b97c43a91
http://europepmc.org/articles/PMC3240600?pdf=render
http://europepmc.org/articles/PMC3240600?pdf=render
Publikováno v:
Cancer Research. 72:4180-4180
The Hippo tumour suppressor pathway is a complex signalling network that controls developmental tissue growth and is frequently deregulated in different human cancers. A key question in Hippo signalling is how the Hippo kinase (MST1/2 in mammals) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2bf0bfea45b3e799dec4edda45898ce
https://doi.org/10.1158/1538-7445.am2012-4180
https://doi.org/10.1158/1538-7445.am2012-4180
Publikováno v:
Current Biology. (17):1587-1594
SummaryThe Salvador-Warts-Hippo (SWH) pathway is an evolutionarily conserved regulator of tissue growth that is deregulated in human cancer [1–3]. Upstream SWH pathway components convey signals from neighboring cells via a core kinase cassette to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b13596c0c9763d4bc9c8f8cb7a53c6