Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Jane Harper"'
Autor:
Jane Harper, Katherine J Adams, Giovanna Bossi, Debbie E Wright, Andrea R Stacey, Nicole Bedke, Ruth Martinez-Hague, Dan Blat, Laure Humbert, Hazel Buchanan, Gabrielle S Le Provost, Zoe Donnellan, Ricardo J Carreira, Samantha J Paston, Luise U Weigand, Martina Canestraro, Joseph P Sanderson, Sophie Botta Gordon-Smith, Kate L Lowe, Karolina A Rygiel, Alex S Powlesland, Annelise Vuidepot, Namir J Hassan, Brian J Cameron, Bent K Jakobsen, Joseph Dukes
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205491 (2018)
Robust preclinical testing is essential to predict clinical safety and efficacy and provide data to determine safe dose for first-in-man studies. There are a growing number of examples where the preclinical development of drugs failed to adequately p
Externí odkaz:
https://doaj.org/article/c3d7165394b5442098ed39f7073a5fbd
Autor:
Neelay J. Kothari, Craig A. Morin, Anita Glennen, Delois Jackson, Jane Harper, Stephanie J. Schrag, Ruth Lynfield
Publikováno v:
Emerging Infectious Diseases, Vol 15, Iss 8, Pp 1279-1281 (2009)
In Minnesota, incidence of invasive group B streptococcal disease was 3 times greater in older adults in long-term care facilities than in older adults in community settings (67.7/100,000 vs. 21.4/100,000) during 2003–2007. The overall case-fatalit
Externí odkaz:
https://doaj.org/article/b11a1d5bc550422fa7e7a8e40883a277
Autor:
Eric J. Bernhard, Sonal Patel, W. Gillies McKenna, Peter O'Neill, Jane Harper, Keith Cengel, Julie Diplexcito, Oliver Sampson, Eric Deutsch, Remko Prevo
Cell signaling initiated at the epidermal growth factor receptor (EGFR), RAS oncoproteins, or PI3K contributes to a common pathway that promotes tumor survival after radiation-induced DNA damage. Inhibition of signaling at the level of EGFR, RAS, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::940c1b31b18f7e5850ddb00c69b908ff
https://doi.org/10.1158/0008-5472.c.6498129.v1
https://doi.org/10.1158/0008-5472.c.6498129.v1
Autor:
Eric J. Bernhard, Sonal Patel, W. Gillies McKenna, Peter O'Neill, Jane Harper, Keith Cengel, Julie Diplexcito, Oliver Sampson, Eric Deutsch, Remko Prevo
Supplementary Figure Legends 1-3, Table Legend 1 from Class I PI3 Kinase Inhibition by the Pyridinylfuranopyrimidine Inhibitor PI-103 Enhances Tumor Radiosensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43db7495eee68955f0d5161c74d4469d
https://doi.org/10.1158/0008-5472.22376202
https://doi.org/10.1158/0008-5472.22376202
Autor:
R. Martinez Hague, Fiona Chester, Jane Harper, S. Griffin, Angharad Lloyd, Emma Baston, R. Mulvaney, Annelise Vuidepot, K. Smith, S. Harper, K. Wiederhold, A.R. Stacey, Andrew Alexander Knox, S. Malla, K.L. Lowe, C.H. Coles, Z. Donnellan, Samantha Paston, Joseph Dukes, Bent K. Jakobsen, R.A. Robinson, M. Aleksic, A. Walker, Michelle L. McCully
Publikováno v:
The Journal of Immunology. 204:1943-1953
The molecular rules driving TCR cross-reactivity are poorly understood and, consequently, it is unclear the extent to which TCRs targeting the same Ag recognize the same off-target peptides. We determined TCR–peptide–HLA crystal structures and, u
Autor:
Jane Houghton, Laura Collins, Koustubh Ranade, Adel Benlahrech, Gabrielle S. Le Provost, Camille Britton-Rivet, Jane Harper, David Depoil, Mariantonella Vardeu
Publikováno v:
Regular and young investigator award abstracts.
Background Tebentafusp (IMCgp100) is a bispecific T cell redirector comprised of an affinity-enhanced TCR recognising melanocyte lineage antigen gp100 and a T cell engaging anti-CD3 scFv domain. Tebentafusp has shown activity as monotherapy in advanc
Autor:
Jane Harper
Vuelve la reina del thriller australiano con un suspense poderoso y brutal. Quemado por el implacable sol del verano austral, el cuerpo de Cameron Bright es hallado sin vida a varias horas en coche de cualquier lugar habitado. Y aunque la policía da
Autor:
Jane Harper
Luke Hadler előbb a feleségével és fiával végez, aztán önmagával is. Kiewarra farmerközössége napi szinten szembesül élet-halál kérdésekkel. Ha valaki egy ilyen helyzetben megtörik, hát…
Autor:
Jane Harper
Öt nő egy céges túra keretein belül kénytelen-kelletlen nekivág az ausztrál bozóterdőnek. Az egyikük, Alice Russell azonban nem tér vissza, és a kollégái mind máshogyan számolnak be a történtekről. A szövetségi rendőrként d
Autor:
Jane Harper
Un thriller adictivo que aborda de forma magistral la corrupción de las empresas y la lucha contra los elementos de cinco mujeres que, en condiciones extremas, harán lo que sea necesario para asegurar su supervivencia y la de sus seres más querido