Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Jane Finch"'
Publikováno v:
Kidney international
Klotho plays an important role in the pathogenesis of cardiovascular disease in chronic kidney disease (CKD). Klotho is highly expressed in the kidney and parathyroid glands, but its presence in the vasculature is debated. Renal Klotho is decreased i
Autor:
Cynthia S. Ritter, León Ferder, Edu Suarez, Helen Liapis, James A. Delmez, Jane Finch, Eduardo Slatopolsky, Sarah Zhang
Publikováno v:
Kidney & blood pressure research
Kidney & Blood Pressure Research, Vol 39, Iss 4, Pp 340-352 (2014)
Kidney & Blood Pressure Research, Vol 39, Iss 4, Pp 340-352 (2014)
Background/Aims: The search for new therapies providing cardiorenal protection in chronic kidney disease (CKD) has led to treatments that combine conventional renin-angiotensin-aldosterone-system inhibitors with other drugs that exhibit potential in
Autor:
Sarah Zhang, Edu Suarez, Jane Finch, Helen Liapis, Duk H. Lee, Cindy Ritter, León Ferder, Eduardo Slatopolsky
Publikováno v:
Kidney International. 84:1145-1153
The role of hyperphosphatemia in the pathogenesis of secondary hyperparathyroidism, cardiovascular disease, and progression of renal failure is widely known. Here we studied effects of dietary phosphate restriction on mortality and vascular calcifica
Autor:
Jane Finch, Wei Yao, Nancy E Lane, Masanori Tokumoto, Mohammad Shahnazari, Hironori Nakamura, Eduardo Slatopolsky
Publikováno v:
American Journal of Physiology-Renal Physiology. 298:F1315-F1322
Calcimimetics activate the calcium-sensing receptor (CaR) and reduce parathyroid hormone (PTH) by increasing the sensitivity of the parathyroid CaR to ambient calcium. The calcimimetic, cinacalcet, is effective in treating secondary hyperparathyroidi
Autor:
Masanori Mukai, Cynthia S. Ritter, Jane Finch, Eduardo Slatopolsky, Masanori Tokumoto, Hironori Nakamura, Masahide Mizobuchi
Publikováno v:
American Journal of Nephrology. 31:292-302
Aims: Left ventricular hypertrophy (LVH) is the most frequent cardiac complication in chronic renal disease. Previous studies implicate elevated serum phosphorus as a risk factor for LVH. Methods: We treated 5/6 nephrectomized rats with enalapril or
Autor:
Ching-Ha Bonnie Kwan, Abdul Rashid Qureshi, Mehdi Rambod, Kam-Tao Philip Li, Manuel Carlos Martins Castro, Joel D. Kopple, Deborah Benner, Karl Tryggvason, Ying Sun, Robert H. Weiss, James S. Kaufman, Jasmin Divers, Hung-Chun Chen, Christiane Rüster, Chih-Ken Chen, Timothy P. Ryan, Paul Winters, Gunter Wolf, Robert T. Neff, Bengt Lindholm, Ajay K. Singh, Mai-Szu Wu, Jaakko Patrakka, D.C. Rao, Jeffrey B. Kopp, Peter Stenvinkel, Ka-Bik Lai, Rosilene M. Elias, Christina Thies, Qunying Guo, Hyun Ju Kim, João Egidio Romão-Junior, Pamela J. Hicks, Edward M. Falta, Jennifer Zitterkoph, Kamyar Kalantar-Zadeh, Frank P. Hurst, Hugo Abensur, Fernand Mac-Moune Lai, James Tacci, Steven C. Hunt, Gang Wang, M. Cignarelli, S. Fariello, Chih-Hung Lee, Masahide Mizobuchi, Sai Ram Keithi-Reddy, Jonas Axelsson, Liqun He, Hiroshi Yamamoto, Zohra Tumur, Timo Pikkarainen, Eric A. Elster, Nobushige Tanaka, Xiaoyan Zhou, Edward D. Frohlich, Juhi Pithia, Barry I. Freedman, Carl D. Langefeld, Sunna Snaedal, Heng Jung Hsu, Mark Leppert, Kevin C. Abbott, Mohamed Cheikhalfraj, Masanori Tokumoto, Eduardo Lyra de Queiroz, Geraldo Lorenzi-Filho, Jin Young Park, Wolfgang Pommer, Toshimitsu Niwa, Rahul M. Jindal, L. Gesualdo, G. Stallone, Sybille Franke, Kai-Ming Chow, George W. Nelson, Susan G. Fisher, Rachelle Bross, Christer Betsholtz, O. Lamacchia, Jessica L. Elder, Dinko Susic, Katarina Truvé, Nosratola D. Vaziri, Chi-Chih Hung, Jane Finch, Jenny Norlin, Antje Wittstock, Tzvetanka Bondeva, Domenic J. Reda, Wan-Chun Liu, D. Camarchio, Alexandra Scholze, Csaba P. Kovesdy, Daniel R. Martin, See-Hyoung Park, Mei-Chuan Kuo, Tejas V. Patel, Neal P. Das, Guillem Genové, Angie Hirter, Cheuk-Chun Szeto, S. Pinnelli, Martin Tepel, Minoru Takemoto, Shang-Jyh Hwang, Hironori Nakamura, James A. Sloand, William S. Beckett, John H. Eckfeldt, Olof Heimbürger, Peter Bárány, Walter Zidek, Cheryl A. Winkler, Eduardo Slatopolsky
Publikováno v:
American Journal of Nephrology. 29:I-VI
Publikováno v:
American Journal of Nephrology. 29:465-472
Aims: This study investigated the protective effect of the angiotensin-converting enzyme inhibitor, enalapril, and the vitamin D analog, paricalcitol, alone or in combination, on cardiac oxidative stress in uremic rats. Methods: Rats were made uremic
Autor:
Masahide Mizobuchi, Jane Finch, Jeremiah J. Morrissey, Tadao Akizawa, Helen Liapis, Eduardo Slatopolsky, Daniel R. Martin
Publikováno v:
Journal of the American Society of Nephrology. 18:1796-1806
Monotherapy with angiotensin-converting enzyme inhibitors has been shown to be beneficial in suppressing the progression of experimentally induced kidney diseases. Whether such therapy provides additional benefits when combined with vitamin D or an a
Autor:
Cynthia S. Ritter, Margaret Clagett-Dame, Hector F. DeLuca, Eduardo Slatopolsky, Jane Finch, Alex J. Brown, Lori A. Plum, Masahide Mizobuchi, Rafal R. Sicinski
Publikováno v:
Journal of Bone and Mineral Research. 22:686-694
Vitamin D analogs are being developed that retain therapeutic effects but are less calcemic and phosphatemic, a concern in CKD patients who are prone to vascular calcification. We tested a new analog of vitamin D, 2MbisP, and found that it suppresses
Autor:
J. Abe, S. Lopez-Hilker, Alex J. Brown, Yasuho Nishii, T. Mori, Adriana Dusso, Eduardo Slatopolsky, Jeremiah J. Morrissey, Jane Finch
Dihydroxyvitamin D (1,25-(OH)2D3) directly suppresses the secretion and synthesis ofPTH in vivo and in cell culture. This compound has been used to treat secondary hyperpara- thyroidism associated with renal failure, but in some patients prolonged tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47644175e894e5ba65d33e2670a2556a
https://doi.org/10.1159/000420167
https://doi.org/10.1159/000420167