Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jane F. Djung"'
Autor:
Steven K. Laughlin, Michael P. Clark, Jane F. Djung, Adam Golebiowski, Todd A. Brugel, Mark Sabat, Roger G. Bookland, Matthew J. Laufersweiler, John C. VanRens, Jennifer A. Townes, Biswanath De, Lily C. Hsieh, Susan C. Xu, Richard L. Walter, Marlene J. Mekel, Michael J. Janusz
Publikováno v:
Bioorganicmedicinal chemistry letters. 15(9)
4-Aryl-3-pyridyl and 4-aryl-3-pyrimidinyl based tumor necrosis factor-alpha (TNF-alpha) inhibitors, which contain a novel isoxazolone five-membered heterocyclic core are described. Many showed sub-micromolar activity against lipopolysaccharide-induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2317a6e0e2ea3c47c2980e8f00d29170
https://pubmed.ncbi.nlm.nih.gov/15837333
https://pubmed.ncbi.nlm.nih.gov/15837333
Publikováno v:
ChemInform. 31
Vinyl pyrimidine 9 and alkynyl pyrimidine 24 undergo base-mediated intramolecular conjugate addition reactions in which a carbamate and a urea, respectively, behave as nitrogen nucleophiles. The cyclic carbamate derived from 9 was converted to 11 via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44091c640fcc9601bba9300f2ca70e93
https://doi.org/10.1002/chin.200051142
https://doi.org/10.1002/chin.200051142
Vinyl and alkynyl pyrimidines as michael acceptors: an approach to a cylindrospermopsin substructure
Publikováno v:
The Journal of organic chemistry. 65(18)
Vinyl pyrimidine 9 and alkynyl pyrimidine 24 undergo base-mediated intramolecular conjugate addition reactions in which a carbamate and a urea, respectively, behave as nitrogen nucleophiles. The cyclic carbamate derived from 9 was converted to 11 via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b60c48dda40bc57a8ff1e756aaff62df
https://pubmed.ncbi.nlm.nih.gov/10970309
https://pubmed.ncbi.nlm.nih.gov/10970309