Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Jane E. Ward"'
Autor:
Simon R. Johnson, Lyn M. Moir, Trang T.B. Nguyen, Janette K. Burgess, Varsha Kanabar, Jane E. Ward, C. C. Ceresa, Brian G. Oliver, Michael Schuliga
Publikováno v:
Pulmonary Pharmacology & Therapeutics. 22:379-387
Asthma is characterized by structural changes in the airways - airway remodelling. These changes include an increase in the bulk of the airway smooth muscle (ASM) and alterations in the profile of extracellular matrix (ECM) proteins in the airway wal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ef18ae5f5a1660d7dd51131d62f594
https://doi.org/10.1016/j.pupt.2008.12.007
https://doi.org/10.1016/j.pupt.2008.12.007
Publikováno v:
Pulmonary Pharmacology & Therapeutics. 22:426-435
Compelling evidence identifies airway smooth muscle (ASM) not only as a target but also a cellular source for a diverse range of mediators underlying the processes of airway narrowing and airway hyperresponsiveness in diseases such as asthma. These i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a0755c76b991c89ba1c63ee961ff03
https://doi.org/10.1016/j.pupt.2008.12.003
https://doi.org/10.1016/j.pupt.2008.12.003
The people who descended on the remote northern Arizona wilderness in the early 1950s to build Glen Canyon Dam and the town of Page were true pioneers. They arrived to find Glen Canyon, a sandy, desolate hilltop with walls over 700 feet deep that had
Autor:
Darren J. Fernandes, Jane E. Ward, Lilly Quan, C.C. Taylor, John V Bonacci, Alastair G. Stewart
Publikováno v:
Pulmonary Pharmacology & Therapeutics. 19:39-46
There is considerable interest in the role of peroxisome proliferator activated receptors (PPARs) as ligand-activated transcription factors in the airways. This study examines the effects of a potent synthetic PPARgamma ligand, rosiglitazone (RG), in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c44feffda47f06af59b945508093009
https://doi.org/10.1016/j.pupt.2005.02.005
https://doi.org/10.1016/j.pupt.2005.02.005
Autor:
Jane E. Ward, James A. Angus
Publikováno v:
Journal of Cardiovascular Pharmacology. 21:804-814
Acute and chronic effects of Nw-nitro-L-arginine (L-NNA), an inhibitor of nitric oxide synthase, were examined on the hindquarter hemodynamics of conscious rabbits. After pharmacological autonomic reflex blockade on four experimental days (days 0, 1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94ea9cc081a74ce602f84dd834690b97
https://doi.org/10.1097/00005344-199305000-00018
https://doi.org/10.1097/00005344-199305000-00018
Publikováno v:
Scopus-Elsevier
Nebivolol, a chemically novel beta 1-adrenoceptor antagonist, acutely lowers blood pressure in spontaneously hypertensive rats, anaesthetised normotensive dogs, and hypertensive patients. We have investigated the actions of dl-nebivolol in five consc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5de0a5242b249fea601d05c86e14e227
https://doi.org/10.1097/00005344-199207000-00015
https://doi.org/10.1097/00005344-199207000-00015
Publikováno v:
Circulation Research. 69:1340-1352
To study the relation between structure and vascular reactivity in mature coronary collateral arteries, we prepared 17 dogs with a casein occluder near the origin of the circumflex coronary artery. At least 24 weeks later, we examined the reactivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea44756dbb3c5bd57a8fd67a5f93592e
https://doi.org/10.1161/01.res.69.5.1340
https://doi.org/10.1161/01.res.69.5.1340
Autor:
Stuart J John Hirst, Jane E. Ward
Publikováno v:
Airway Smooth Muscle in Asthma and COPD: Biology and Pharmacology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::071e5d31d4d029c01356219ad8123c30
https://doi.org/10.1002/9780470754221.ch6
https://doi.org/10.1002/9780470754221.ch6
Autor:
Tiffany L Bamford, John W Wilson, M. C. F. Pain, Trudi Harris, Jane E. Ward, Alastair G. Stewart, David Smallwood, Colin F. Robertson, Thai Tran, Anja Mast
Publikováno v:
The European respiratory journal. 32(2)
Airway mesenchymal cells, such as myofibroblasts and airway smooth muscle cells, contribute to inflammation, airway remodelling and hyperresponsiveness in asthma by excessive proliferation and inflammatory mediator production. Using endobronchial bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b29acb9627750ddec06540a586a87620
https://pubmed.ncbi.nlm.nih.gov/18353854
https://pubmed.ncbi.nlm.nih.gov/18353854
Autor:
Jane E. Ward, Xiahui Tan
Publikováno v:
PPAR Research, Vol 2007 (2007)
PPAR Research
PPAR Research
Inflammation is a major component in the pathology of chronic lung diseases, including asthma. Anti-inflammatory treatment with corticosteroids is not effective in all patients. Thus, new therapeutic options are required to control diverse cellular f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b013a58c359bffb4ee91ef4534c0998
https://doaj.org/article/3bdba4c1d71e4226b32a0e0d68a6fd37
https://doaj.org/article/3bdba4c1d71e4226b32a0e0d68a6fd37