Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jane E. Guido"'
Autor:
Jane E. Guido, Xiao-Qing Yang
Publikováno v:
Advances in Food Technology and Nutritional Sciences - Open Journal. :S34-S44
Autor:
Bruce A. Stiemsma, Antony J. Williams, Eduard R. Martirosian, Thomas J. Thamann, Sergey G. Molodtsov, Gary E. Martin, David J. Russell, Brian D. Kaluzny, Paul L. Schiff, Chad E. Hadden, Ronald C. Crouch, Kirill A. Blinov, Mikhail E. Elyashberg, Jane E. Guido, Wayne K. Duholke
Publikováno v:
Journal of Heterocyclic Chemistry. 39:1241-1250
Identification of degradants of pharmaceuticals is a necessary challenge of the drug development process following the subjection of candidate molecules to a variety of physico-chemical stresses. It would be desirable to be able to conduct such studi
Autor:
Thomas J. Thamann, Wayne K. Duholke, Brian D. Kaluzny, Russell H. Robins, Jane E. Guido, Bruce A. Pearlman, Frank W. Crow, Chad E. Hadden, Gary E. Martin
Publikováno v:
Journal of Heterocyclic Chemistry. 36:1107-1114
TipranavirTM (PNU-140690) is a protease inhibitor under clinical investigation for the treatment of human acquired immunodeficiency syndrome (AIDS). During scale-up synthesis of clinical quantities of the bulk drug, a colored, transient by-product of
Autor:
Paul L. Schiff, Wayne K. Duholke, Russell H. Robins, Chad E. Hadden, Jane E. Guido, Gary E. Martin, Maged H. M. Sharaf
Publikováno v:
Journal of Heterocyclic Chemistry. 36:525-531
The nmr analysis of a mixture of cryptolepinone and it's 5(N)-oxide in a 1.5:1 ratio is discussed. The differentiation of the resonances of the two similar compounds, and elucidation of the unknown 5(N)-oxide relied primarily on IDR-GHSQC-TOCSY data
Autor:
Sims Sandra M, Brian E. Thompson, Thomas J. Thamann, Jane E. Guido, Tsutoma Tahara, Wayne K. Duholke, Yukimi Noro, Kathleen A. Farley, Brian D. Kaluzny, Russell H. Robins, Phil B. Bowman, Gary E. Martin, Toshihide Nishimura
Publikováno v:
Journal of Heterocyclic Chemistry. 36:265-270
Parenteral formulations of linezolid (PNU-100766), a novel (S)-3-(4′-fluorophenyl)-5-N-acetamidomethyloxazolidin-2-one antibiotic, were subjected to photo-stability testing as required by ICH guidelines. Direct, reversed phase chromatographic evalu
Autor:
Thomas J. Thamann, Jane E. Guido, Bowman Phil B, Kathleen A. Farley, Frank W. Crow, Brenda S. Vonderwell, Russell H. Robins, Gary E. Martin, Richard F. Smith, Wayne K. Duholke, Sandra M. Sims, Jay C. Brumfield
Publikováno v:
Magnetic Resonance in Chemistry. 36:S11-S16
A method is described for unequivocally establishing the site of N-oxidation which relies on the relatively large downfield shift of aliphatic nitrogen resonances following oxidation. The technique described is based on 15N at natural abundance and d
Autor:
Jane E. Guido, Russell H. Robins
Publikováno v:
Rapid Communications in Mass Spectrometry. 11:1661-1666
Autor:
Robert T. Rosen, Nicholi Vorsa, Kent A Mills, David Russell, Jane E Guido, Irina O. Vvedenskaya
Publikováno v:
Journal of agricultural and food chemistry. 52(2)
Flavonoids were extracted from cranberry powder with acetone and ethyl acetate and subsequently fractionated with Sephadex LH-20 column chromatography. The fraction eluted with a 60% methanol solution was composed primarily of phenolic constituents w
Autor:
Albert N. Tackie, Charles H. Phoebe, Russell H. Robins, Maged H. M. Sharaf, Gary E. Martin, Chad E. Hadden, Paul L. Schiff, Jane E. Guido
Publikováno v:
Journal of natural products. 62(2)
A new alkaloid has been isolated from extracts of the West African plant Cryptolepis sanguinolenta and identified by submicro NMR techniques as 11-isopropylcryptolepine (1). The unusual incorporation of the isopropyl group at the 11-position of the i
Autor:
Albert N. Tackie, Russell H. Robins, Paul L. Schiff, Maged H. M. Sharaf, Jane E. Guido, Gary E. Martin
Publikováno v:
Journal of natural products. 61(5)
Quantities of material required for structural analysis were reduced substantially following the introduction of 3 mm microinverse and microdual NMR probes in 1992. We now report the first very low-level results obtainable with a new 1.7 mm submicro-