Výsledky vyhledávání - "Jane E. Grundy"

Akademický článek

Cytomegalovirus Pathogenesis in Transplantation

Autor: Jane E Grundy

Publikováno v: Canadian Journal of Infectious Diseases, Vol 4, Iss Suppl C, Pp 11-17 (1993)

Cytomegalovirus (CMV) infection is an important cause of morbidity and mortality in the immunocompromised; however, even within this group of patients, infection with CMV is not synonymous with disease. A number of factors affect the pathogenicity of

Externí odkaz: https://doaj.org/article/2dce75d20be14682b4685901e3053b00

Zobrazit plný text záznamu

Two clinical isolates and the Toledo strain of cytomegalovirus contain endothelial cell tropic variants that are not present in the AD169, Towne, or Davis strains

Autor: Luci P. MacCormac, Jane E. Grundy

Publikováno v: Journal of Medical Virology. 57:298-307

The highly fibroblast-passaged AD169, Towne, and Davis strains of cytomegalovirus (CMV) were found to have a restricted capacity to infect endothelial cells in vitro. Although such replication could be increased by a combination of low speed centrifu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::81b1dcd854f06f9eea02e170ffe7b3ce
https://doi.org/10.1002/(sici)1096-9071(199903)57:3<298::aid-jmv14>3.0.co

Zobrazit plný text záznamu

Natural Killer Cell Lysis of Cytomegalovirus (CMV)-Infected Cells Correlates with Virally Induced Changes in Cell Surface Lymphocyte Function-Associated Antigen-3 (LFA-3) Expression and Not with the CMV-Induced Down-Regulation of Cell Surface Class I HLA

Autor: Jean M. Fletcher, H. Grant Prentice, Jane E. Grundy

Publikováno v: The Journal of Immunology. 161:2365-2374

CMV and other viruses down-regulate the cell surface expression of class I HLA, and while this allows them to evade CTL, it may make infected cells more susceptible to lysis by NK cells, due to the failure to engage class I inhibitory receptors on th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4e139a185960c4ed7946c125dfa4d1d5
https://doi.org/10.4049/jimmunol.161.5.2365

Zobrazit plný text záznamu

Human Cytomegalovirus Induces an Fe Receptor (Fc R) in Endothelial Cells and Fibroblasts that Is Distinct from the Human Cellular Fc Rs

Autor: Jane E. Grundy, Luci P. MacCormac

Publikováno v: Journal of Infectious Diseases. 174:1151-1161

The expression of a trypsin-sensitive receptor for the Fc portion of IgG (Fc gammaR) was demonstrated by flow cytometry on the surface of human umbilical vein endothelial cells and fibroblasts infected with human cytomegalovirus (CMV). Double-labelin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b242f526dda795b5427b7698c03b75b3
https://doi.org/10.1093/infdis/174.6.1151

Zobrazit plný text záznamu

CYTOMEGALOVIRUS INDUCED UP-REGULATION OF LFA-3 (CD58) AND ICAM-1(CD54) IS A DIRECT VIRAL EFFECT THAT IS NOT PREVENTED BY GANCICLOVIR OR FOSCARNET TREATMENT1

Autor: Jane E. Grundy, Jennifer L. Craigen

Publikováno v: Transplantation. 62:1102-1108

Cytomegalovirus (CMV) is a major pathogen in transplant recipients and AIDS patients, and the virus may also play a role in allograft rejection. Previous work from this laboratory demonstrated increased cell surface expression of the adhesion molecul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::28e2b0c6415de4e2b5c96eed7b1bd686
https://doi.org/10.1097/00007890-199610270-00014

Zobrazit plný text záznamu

Down-regulation of the class I HLA heterodimer and beta2-microglobulin on the surface of cells infected with cytomegalovirus

Autor: Penelope D. Barnes, Jane E. Grundy

Publikováno v: Journal of General Virology. 73:2395-2403

Cytotoxic T cell recognition of virus-infected cells requires the presentation of viral peptides by class I HLA molecules on the cell surface. We report here that cytomegalovirus (CMV) infection of human fibroblasts results in a progressive decrease

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebda2555b4bcce34577091d5c484a773
https://doi.org/10.1099/0022-1317-73-9-2395

Zobrazit plný text záznamu

Virologic and Pathogenetic Aspects of Cytomegalovirus Infection

Autor: Jane E. Grundy

Publikováno v: Clinical Infectious Diseases. 12:S711-S719

Cytomegalovirus (CMV) is a ubiquitous agent that rarely causes disease in immunocompetent humans but is an important cause of morbidity and mortality in the immunocompromised. A number of host and viral factors are associated with pathology following

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f50badeb1d29d50be967cbfeb766dfe
https://doi.org/10.1093/clinids/12.supplement_7.s711

Zobrazit plný text záznamu

Cytomegalovirus in the Lungs of Patients with AIDS: Respiratory Pathogen or Passenger?

Autor: Gary Patou, Jane E. Grundy, A. B. Millar, Ian V. D. Weller, S. J. G. Semple, David R. Katz, Robert F. Miller

Publikováno v: American Review of Respiratory Disease. 141:1474-1477

A total of 166 consecutive clinical episodes of pneumonitis in patients with acquired immune deficiency syndrome (AIDS) or antibody positive for human immune deficiency virus (HIV) were investigated for evidence of cytomegalovirus (CMV) infection in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c76682638ab4c1b1ff2b8c594cd182ae
https://doi.org/10.1164/ajrccm/141.6.1474

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání