Zobrazeno 1 - 10
of 358
pro vyhledávání: '"Jane E. Freedman"'
Autor:
Tianxiao Huan, Roby Joehanes, Jian Rong, Ming-Huei Chen, Rima Mustafa, Abbas Dehghan, Mohsen Ghanbari, Hannah Karlin, Shih-Jen Hwang, Paul Courchesne, Martin G. Larson, Andrew D. Johnson, Jane E. Freedman, Daniel Levy
Publikováno v:
iScience, Vol 27, Iss 10, Pp 110988- (2024)
Summary: MicroRNAs, crucial in regulating protein-coding gene expression, are implicated in various diseases. We performed a genome-wide association study of plasma miRNAs (ex-miRNAs) in 3,743 Framingham Heart Study (FHS) participants and identified
Externí odkaz:
https://doaj.org/article/0af562d70c8345678e66f7cd70367565
Autor:
Hannah Karlin, Meera Sooda, Martin Larson, Jian Rong, Tianxiao Huan, Michelle M. J. Mens, Frank J. A. van Rooij, M. Arfan Ikram, Paul Courchesne, Jane E. Freedman, Roby Joehanes, Gregory P. Mueller, Maryam Kavousi, Mohsen Ghanbari, Daniel Levy
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 12 (2024)
Background Extracellular microRNAs (miRNAs) are a class of noncoding RNAs that remain stable in the extracellular milieu, where they contribute to various physiological and pathological processes by facilitating intercellular signaling. Previous stud
Externí odkaz:
https://doaj.org/article/e66624d074dc42bb91bda8fc2daebc56
Autor:
Ravi V. Shah, Shih‐Jen Hwang, Venkatesh L. Murthy, Shilin Zhao, Kahraman Tanriverdi, Priya Gajjar, Kevin Duarte, Mark Schoenike, Robyn Farrell, Liana C. Brooks, Deepa M. Gopal, Jennifer E. Ho, Nicholas Girerd, Ramachandran S. Vasan, Daniel Levy, Jane E. Freedman, Gregory D. Lewis, Matthew Nayor
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 21 (2023)
Background While exercise impairments are central to symptoms and diagnosis of heart failure with preserved ejection fraction (HFpEF), prior studies of HFpEF biomarkers have mostly focused on resting phenotypes. We combined precise exercise phenotype
Externí odkaz:
https://doaj.org/article/2306c9218f714b4c81c636939db51d48
Autor:
Fulya Ekiz Kanik, Iris Celebi, Derin Sevenler, Kahraman Tanriverdi, Nese Lortlar Ünlü, Jane E. Freedman, M. Selim Ünlü
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract MicroRNAs (miRNAs) are a family of noncoding, functional RNAs. With recent developments in molecular biology, miRNA detection has attracted significant interest, as hundreds of miRNAs and their expression levels have shown to be linked to va
Externí odkaz:
https://doaj.org/article/2160c8073dd34992840e4382ef7a1d93
Autor:
G.Michael Felker, Peter Buttrick, Anthony Rosenzweig, E. Dale Abel, Larry A. Allen, Michael Bristow, Saumya Das, Adam D. DeVore, Stavros G. Drakos, James C. Fang, Jane E. Freedman, Adrian F. Hernandez, Dean Y. Li, Timothy A. McKinsey, Christopher Newton‐Cheh, Joseph G. Rogers, Ravi V. Shah, Svati H. Shah, Josef Stehlik, Craig H. Selzman
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 18 (2022)
Heart failure remains among the most common and morbid health conditions. The Heart Failure Strategically Focused Research Network (HF SFRN) was funded by the American Heart Association to facilitate collaborative, high‐impact research in the field
Externí odkaz:
https://doaj.org/article/fbf3fa3979cc4affabde739b5bcf3cec
Autor:
Tianxiao Huan, Michael Mendelson, Roby Joehanes, Chen Yao, Chunyu Liu, Ci Song, Anindya Bhattacharya, Jian Rong, Kahraman Tanriverdi, Joshua Keefe, Joanne M. Murabito, Paul Courchesne, Martin G. Larson, Jane E. Freedman, Daniel Levy
Publikováno v:
Epigenetics, Vol 15, Iss 1-2, Pp 183-198 (2020)
DNA methylation (DNAm) and microRNAs (miRNAs) have been implicated in a wide-range of human diseases. While often studied in isolation, DNAm and miRNAs are not independent. We analyzed associations of expression of 283 miRNAs with DNAm at >400K CpG s
Externí odkaz:
https://doaj.org/article/ac5fe20ffd344db3b731af4b904a3a44
Autor:
Sriram Krishnaswamy, Walter Ageno, Yaseen Arabi, Tiziano Barbui, Suzanne Cannegieter, Marc Carrier, Audrey C. Cleuren, Peter Collins, Laurence Panicot‐Dubois, Jane E. Freedman, Kathleen Freson, Philip Hogg, Andra H. James, Colin A. Kretz, Michelle Lavin, Frank W. G. Leebeek, Weikai Li, Coen Maas, Kellie Machlus, Michael Makris, Ida Martinelli, Leonid Medved, Marguerite Neerman‐Arbez, James S. O’Donnell, Jamie O'Sullivan, Madhvi Rajpurkar, Verena Schroeder, Paul Clinton Spiegel Jr, Simon J. Stanworth, Laura Green, Anetta Undas
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 5, Pp n/a-n/a (2021)
Abstract This year's Congress of the International Society of Thrombosis and Haemostasis (ISTH) was hosted virtually from Philadelphia July 17–21, 2021. The conference, now held annually, highlighted cutting‐edge advances in basic, population and
Externí odkaz:
https://doaj.org/article/f4e8d27c7559432aabed3d4087dfb05b
Autor:
Milka Koupenova, Eric Mick, Heather A. Corkrey, Anupama Singh, Selim E. Tanriverdi, Olga Vitseva, Daniel Levy, Allison M. Keeler, Marzieh Ezzaty Mirhashemi, Mai K. ElMallah, Mark Gerstein, Joel Rozowsky, Kahraman Tanriverdi, Jane E. Freedman
Publikováno v:
iScience, Vol 19, Iss , Pp 916-926 (2019)
Summary: The presence of nonhuman RNAs in man has been questioned and it is unclear if food-derived miRNAs cross into the circulation. In a large population study, we found nonhuman miRNAs in plasma by RNA sequencing and validated a small number of p
Externí odkaz:
https://doaj.org/article/7c9e39664021410ea301039df7e1355c
Autor:
Peter McAnena, Kahraman Tanriverdi, Catherine Curran, K. Gilligan, Jane E. Freedman, James A. L. Brown, Michael J. Kerin
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Breast cancer is the leading cause of cancer related death in women, with metastasis the principle cause of mortality. New non-invasive prognostic markers are needed for the early detection of metastasis, facilitating treatment de
Externí odkaz:
https://doaj.org/article/87a42f735c70488f966154094f16116e
Autor:
Milka Koupenova, Heather A. Corkrey, Olga Vitseva, Giorgia Manni, Catherine J. Pang, Lauren Clancy, Chen Yao, Jeffrey Rade, Daniel Levy, Jennifer P. Wang, Robert W. Finberg, Evelyn A. Kurt-Jones, Jane E. Freedman
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Influenza viremia is rare in human blood and not well studied. Here, the authors show that influenza can be found in human platelets and that platelet engulfment of influenza A results in TLR7-dependent C3 release, which in turn promotes neutrophil-D
Externí odkaz:
https://doaj.org/article/af0f74c3b44c481eb070539a669dd2de