Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Jane E. Dixon"'
Autor:
Hong-Sheng Wang, Ira S. Cohen, David McKinnon, Jane E. Dixon, Steven Lypen, Zongming Pan, Barbara Rosati
Publikováno v:
The Journal of Physiology. 533:119-125
Expression of four members of the KChIP family of potassium channel β subunits was examined in canine heart. Only one member of the gene family, KChIP2, was expressed in heart. There was a steep gradient of KChIP2 mRNA expression across the canine v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09f69764b23d5ec9ba2ef327d8cdeee4
https://doi.org/10.1111/j.1469-7793.2001.0119b.x
https://doi.org/10.1111/j.1469-7793.2001.0119b.x
Autor:
Randy S. Wymore, Wenmei Shi, David McKinnon, Barry S. Brown, Hong-Sheng Wang, Zongming Pan, Jane E. Dixon, Ira S. Cohen
Publikováno v:
Science. 282:1890-1893
The M-current regulates the subthreshold electrical excitability of many neurons, determining their firing properties and responsiveness to synaptic input. To date, however, the genes that encode subunits of this important channel have not been ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010cac7254d3cbf5c3dce640c20f3f69
https://doi.org/10.1126/science.282.5395.1890
https://doi.org/10.1126/science.282.5395.1890
Publikováno v:
Circulation Research. 80:261-268
The human K + channel gene, HERG, has been linked to the type 2 form of the autosomal dominant long-QT syndrome and has been suggested to encode the fast component of the delayed rectifier K + current (I Kr ) found in heart. To date, the published el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79369921ea2aaf5d41ee065fc73a31c0
https://doi.org/10.1161/01.res.80.2.261
https://doi.org/10.1161/01.res.80.2.261
Autor:
Jeanne M. Nerbonne, Dianne M. Barry, Jane E. Dixon, Haodong Xu, David McKinnon, John P. Merlie, James S. Trimmer
Publikováno v:
The Journal of General Physiology
In the experiments here, the developmental expression of the functional Ca(2+)-independent, depolarization-activated K+ channel currents, Ito and IK, and of the voltage-gated K+ channel (Kv) alpha subunits, Kv1.2, Kv1.4, Kv1.5, Kv2.1, and Kv4.2 in ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::670c6477daea8b44fdab322e5283c8b0
https://doi.org/10.1085/jgp.108.5.405
https://doi.org/10.1085/jgp.108.5.405
Autor:
B. Holmes, Hong-Zhan Wang, David McKinnon, Jane E. Dixon, Joan Zuckerman, William B. Benjamin, Hangang Yu, Rigel T. Wymore, Randy S. Wymore, Ira S. Cohen, M. R. El-Maghrabi, Richard B. Robinson, Wenmei Shi, Irina A. Potapova, Zongming Pan, Jiying Wu
Publikováno v:
Circulation research. 88(12)
Abstract —The HCN family of ion channel subunits underlies the currents I f in heart and I h and I q in the nervous system. In the present study, we demonstrate that minK-related peptide 1 (MiRP1) is a β subunit for the HCN family. As such, it enh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f8ec55c69241f116f29a55686b9071c
https://pubmed.ncbi.nlm.nih.gov/11420311
https://pubmed.ncbi.nlm.nih.gov/11420311
Publikováno v:
The Journal of physiology. 531(Pt 2)
The region of alternative splicing in the KCNQ2 potassium channel gene was determined by RNase protection analysis of KCNQ2 mRNA transcripts. Systematic analysis of KCNQ2 alternative splice variant expression in rat superior cervical ganglia revealed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41659eed99ab5799e82f6a2d9b6a0e5c
https://pubmed.ncbi.nlm.nih.gov/11230508
https://pubmed.ncbi.nlm.nih.gov/11230508
Autor:
David McKinnon, Richard B. Robinson, Ira S. Cohen, Wenmei Shi, Jiying Wu, Hangang Yu, Randy S. Wymore, Jane E. Dixon, Rigel T. Wymore, Zongming Pan
Publikováno v:
Circulation research. 85(1)
Abstract —HCN cation channel mRNA expression was determined in the rabbit heart and neonatal and adult rat ventricle using RNase protection assays. In the rabbit SA node, the dominant HCN transcript is HCN4, representing >81% of the total HCN messa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2279014dccb9d8f527f96bf0d972646c
https://pubmed.ncbi.nlm.nih.gov/10400919
https://pubmed.ncbi.nlm.nih.gov/10400919
Autor:
Evgeny P. Anyukhovsky, Randy S. Wymore, Hangang Yu, Alexei Shvilkin, Michael R. Rosen, Jane E. Dixon, Ira S. Cohen, Junyuan Gao, Peter Danilo, David McKinnon, Eugene A. Sosunov, Motoki Hara
Publikováno v:
Circulation. 99(14)
Background —Cardiac memory refers to an altered T-wave morphology induced by ventricular pacing or arrhythmias that persist for variable intervals after resumption of sinus rhythm. Methods and Results —We induced long-term cardiac memory (LTM) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74ba0ce260e01c9894a1a8dbbef61024
https://pubmed.ncbi.nlm.nih.gov/10199889
https://pubmed.ncbi.nlm.nih.gov/10199889
Autor:
Ira S. Cohen, Y. Wang, Richard T. Mathias, Junyuan Gao, R. T. Wymore, David McKinnon, G. J. Baldo, Randy S. Wymore, Jane E. Dixon
Publikováno v:
The Journal of physiology. 516
1. Guinea-pig ventricle was used in the RNase protection assays to determine which alpha-isoforms of the Na+-K+ pumps are present, and ventricular myocytes were used in whole cell patch clamp studies to investigate the actions of alpha- and beta-adre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78362aa47049f0eeb2b0a6cb01657666
https://pubmed.ncbi.nlm.nih.gov/10087338
https://pubmed.ncbi.nlm.nih.gov/10087338
Autor:
Stefan Kääb, D. Ashen, Gordon F. Tomaselli, J. Duc, Michael Nabauer, Dirk J. Beuckelmann, David McKinnon, Jane E. Dixon, Gerhard Steinbeck
Publikováno v:
Circulation. 98(14)
Background —Despite advances in medical therapy, congestive heart failure remains a major cause of death in the developed world. A disproportionate number of the deaths of patients with heart failure are sudden and presumed to be arrhythmic. Heart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20bbf3b03a0c66c0793341a5e86388e7
https://pubmed.ncbi.nlm.nih.gov/9760292
https://pubmed.ncbi.nlm.nih.gov/9760292