Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jane E Strasser"'
Autor:
Tonyia Eaves-Pyles, Heng-Fu Bu, Xiao-di Tan, Yingzi Cong, Jignesh Patel, Robert A Davey, Jane E Strasser
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24869 (2011)
Bacteria release flagellin that elicits innate responses via Toll-like receptor 5 (TLR5). Here, we investigated the fate of apically administrated full length flagellin from virulent and avirulent bacteria, along with truncated recombinant flagellin
Externí odkaz:
https://doaj.org/article/85cfc6fa8a704b51ac9a3ce8fcf5b68b
Publikováno v:
Clinical and Translational Science. 6:317-320
Emphasis has been placed on assessing the efficiency of clinical and translational research as part of the National Institutes of Health (NIH) goal to "improve human health." Improvements identified and implemented by individual organizations cannot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f695c4cae7bd7cf7e3f861d0ba6eb3cb
https://doi.org/10.1111/cts.12051
https://doi.org/10.1111/cts.12051
Autor:
Cynthia Ann Fuller, Michael J. Flagler, Alison A. Weiss, Jane E. Strasser, Christine A. Pellino
Publikováno v:
Infection and Immunity. 79:1329-1337
Purified Shiga toxin (Stx) alone is capable of producing systemic complications, including hemolytic-uremic syndrome (HUS), in animal models of disease. Stx includes two major antigenic forms (Stx1 and Stx2), with minor variants of Stx2 (Stx2a to -h)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c231c7e440798c72f0ea0f6b2f1b9607
https://doi.org/10.1128/iai.01182-10
https://doi.org/10.1128/iai.01182-10
Autor:
Jeff Fairman, Marla Lay, Fernando J. Bravo, Claudia Chalk, Nicholas Farley, Rhonda D. Cardin, David I. Bernstein, Jane E. Strasser
Publikováno v:
Clinical and Vaccine Immunology. 16:699-705
Development of a herpes simplex virus (HSV) vaccine is a priority because these infections are common. It appears that potent adjuvants will be required to augment the immune response to subunit HSV vaccines. Therefore, we evaluated cationic liposome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bf997acb94e61668595bbd77bb12a9f
https://doi.org/10.1128/cvi.00370-08
https://doi.org/10.1128/cvi.00370-08
Autor:
Jane E. Strasser, Michael G. Meador, Chin-Fun Chu, Christal G. Young, Nigel Bourne, Gregg N. Milligan
Publikováno v:
Journal of Reproductive Immunology. 78:58-67
The ability of antibody (Ab) to modulate HSV pathogenesis is well recognized but the mechanisms by which HSV-specific IgG antibodies protect against genital HSV-2 disease are not well understood. The requirement for Ab interactions with Fcgamma recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e8e3e30df9a7bf0b908123c9fcf278
https://doi.org/10.1016/j.jri.2007.08.004
https://doi.org/10.1016/j.jri.2007.08.004
Publikováno v:
Infection and Immunity. 75:760-765
Hemolytic-uremic syndrome (HUS), the life-threatening complication following infection by the intestinal pathogen Escherichia coli O157:H7, is due to the ability of the pathogen to produce toxins in the Shiga toxin (Stx) family. Activated neutrophils
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59dedb056f353ac2da68f5a8b611c30f
https://doi.org/10.1128/iai.01594-06
https://doi.org/10.1128/iai.01594-06
Publikováno v:
Infection and Immunity. 74:1977-1983
The presence of commensal flora reduced colonization of Escherichia coli O157:H7 and production of Shiga toxin (Stx) in the murine intestine. Stx production was not detected in mice colonized with E. coli that were resistant to the Shiga toxin phage,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8a7a6d348247a6126d526c722952319
https://doi.org/10.1128/iai.74.3.1977-1983.2006
https://doi.org/10.1128/iai.74.3.1977-1983.2006
Autor:
Hermine I. Brunner, Claudia Chalk, Gregg N. Milligan, Raphael Hirsch, Sherry Thornton, Brenna Carey, Monica L. DeLay, Jane E. Strasser, Kristen L. Dudley-McClain
Publikováno v:
Clinical Immunology. 116:65-76
CD8+ T lymphocytes recognize tumor and viral antigens bound to class I major histocompatibility complexes (MHC). Tumors and viruses may evade detection by preventing antigen presentation. The present study was designed to determine whether a soluble
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353b5232f1d4f602a0cd2a5c70125d87
https://doi.org/10.1016/j.clim.2005.02.013
https://doi.org/10.1016/j.clim.2005.02.013
Publikováno v:
Clinical and Translational Science. 6:176-178
Effective clinical and translational research is an essential component of improving human health as delineated in the National Institutes of Health (NIH) roadmap, 1,2 yet efficiently conducting that research remains problematic. 3,4 Challenges inclu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9341cbc96265002a591b7cd96a8dfe13
https://doi.org/10.1111/cts.12074
https://doi.org/10.1111/cts.12074
Regulation of the Macrophage Vacuolar ATPase and Phagosome-Lysosome Fusion by Histoplasma capsulatum
Autor:
Jane E. Strasser, Simon L. Newman, Georgianne M. Ciraolo, Randal E. Morris, Michael L. Howell, Gary E. Dean
Publikováno v:
The Journal of Immunology. 162:6148-6154
Histoplasma capsulatum (Hc) maintains a phagosomal pH of about 6.5. This strategy allows Hc to obtain iron from transferrin, and minimize the activity of macrophage (Mø) lysosomal hydrolases. To determine the mechanism of pH regulation, we evaluated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a1db0f464498da35b4339e0b32b3721
https://doi.org/10.4049/jimmunol.162.10.6148
https://doi.org/10.4049/jimmunol.162.10.6148