Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jane E McCausland"'
Publikováno v:
Pediatric Nephrology. 13:347-354
The kidney is derived from two tissue sources and develops through a series of mesenchymal-epithelial transitions and epithelial-mesenchymal interactions to form an epithelial tubular organ embedded in an interstitium derived from mesenchyme. The pri
Publikováno v:
Nephrology. 2:305-313
Summary: Quantitative methods are frequently used to analyse the structure of renal glomeruli. However, on most occasions, measurements are made on glomerular profiles (the two-dimensional samples of glomeruli seen in histological sections), and prov
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 23:88-92
1. This brief review examines the evidence that angiotensin II (AngII) is essential for kidney development. 2. Several components of the renin-angiotensin system (RAS) are detected in the foetal kidney early in development. 3. Angiotensin II is essen
Autor:
Frederick A.O. Mendelsohn, Peter J. Harris, G.Peter Aldred, Daine Alcorn, Jialong Zhuo, Jane E McCausland
Publikováno v:
Nephrology. 1:511-525
Summary: Angirotensin II (AII) is a powerful humoral regulator of body fluid and electrolyte balance and arterial blood pressure. In the kidney, All influences renal haemodynamics and proximal tubular reabsorption of sodium through activation of All
Publikováno v:
Hypertension. 23:838-843
Angiotensin II receptor binding sites in type 1 interstitial cells in the inner stripe of the outer medulla are readily labeled in vitro by the radioligand but not in vivo after systemic radioligand administration. In anesthetized rats, we investigat
Publikováno v:
Cell and Tissue Research. 274:597-604
Scanning and transmission electron microscopy were used to study the ultrastructural characteristics and positions of granulated peripolar cells in newborn lamb kidney. Following tissue fixation by vascular perfusion in situ, the vascular pole region
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 23:552-554
SUMMARY 1. Chronic angiotensin converting enzyme (ACE) inhibition or AT1 antagonism during postnatal development in the rat has been shown to cause renal tubular and vascular damage, particularly in the outer medulla. 2. The effects of ACE inhibition
Publikováno v:
Kidney International. 46(6):1483-1485
The renin-angiotensin system has been implicated in regulating renal medullary and papillary microcirculation and urinary concentrating processes, but the mechanisms by which angiotensin II (Mg II) exerts its influences in the renal medulla are not w
Autor:
Jeffrey D Zajac, Marjorie Dunlop, Charles L. Hardy, Jane E McCausland, Richard G Larkins, Wendy C. Burns, Timothy E. Adams, Daniel P K Ng, Evelyne Muggli, Nicole F Kerr, Daine Alcorn
Publikováno v:
Endocrine. 18(1)
Studies using pharmacologic inhibitors have implicated the enzyme aldose reductase in the pathogenesis of albuminuria and diabetic renal disease. However, a clear conclusion is not easily drawn from such studies since these pharmacologic inhibitors h
Autor:
Jane E McCausland, Jialong Zhuo, Anthony L. Albiston, Karen M. Moritz, Aldona Butkus, E. M. Wintour, Michelle L. Giles, Daine Alcorn
Publikováno v:
Kidney international. 52(3)
Ontogeny of angiotensin II receptors, types 1 and 2, in ovine mesonephros and metanephros. By RNAse protection assay, hybridization histochemistry, and in vitro autoradiography it was shown that both mRNA and protein for AT 1 and AT 2 receptors were