Zobrazeno 1 - 10
of 326
pro vyhledávání: '"Jane E Freedman"'
Autor:
Aditya Vaze, Khanh-Van Tran, Kahraman Tanriverdi, Mayank Sardana, Darleen Lessard, J Kevin Donahue, Bruce Barton, Gerard Aurigemma, Steven A Lubitz, Honghuang Lin, George H Nasr, Amiya Mandapati, Emelia J Benjamin, Ramachandran S Vasan, Jane E Freedman, David D McManus
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0236960 (2020)
BackgroundCirculating microRNAs may reflect or influence pathological cardiac remodeling and contribute to atrial fibrillation (AF).ObjectiveThe purpose of this study was to identify candidate plasma microRNAs that are associated with echocardiograph
Externí odkaz:
https://doaj.org/article/2e02f92b382946e9a14035522a92cb3f
Autor:
Joel Salinas, Honghuang Lin, Hugo J Aparico, Tianxiao Huan, Chunyu Liu, Jian Rong, Alexa Beiser, Jayandra J Himali, Jane E Freedman, Martin G Larson, Jonathan Rosand, Hermona Soreq, Daniel Levy, Sudha Seshadri
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0219261 (2019)
Emerging evidence suggests microRNAs (miRNAs) may play an important role in explaining variation in stroke risk and recovery in humans, yet there are still few longitudinal studies examining the association between whole blood miRNAs and stroke. Acco
Externí odkaz:
https://doaj.org/article/51ba8c55a1ec4ab2ae7af32c61f7a428
Autor:
Tianxiao Huan, Roby Joehanes, Jian Rong, Ming-Huei Chen, Rima Mustafa, Abbas Dehghan, Mohsen Ghanbari, Hannah Karlin, Shih-Jen Hwang, Paul Courchesne, Martin G. Larson, Andrew D. Johnson, Jane E. Freedman, Daniel Levy
Publikováno v:
iScience, Vol 27, Iss 10, Pp 110988- (2024)
Summary: MicroRNAs, crucial in regulating protein-coding gene expression, are implicated in various diseases. We performed a genome-wide association study of plasma miRNAs (ex-miRNAs) in 3,743 Framingham Heart Study (FHS) participants and identified
Externí odkaz:
https://doaj.org/article/0af562d70c8345678e66f7cd70367565
Autor:
Ravi Shah, Kahraman Tanriverdi, Daniel Levy, Martin Larson, Mark Gerstein, Eric Mick, Joel Rozowsky, Robert Kitchen, Venkatesh Murthy, Ekaterina Mikalev, Jane E Freedman
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153691 (2016)
MicroRNA (miRNA) expression has rapidly grown into one of the largest fields for disease characterization and development of clinical biomarkers. Consensus is lacking in regards to the optimal sample source or if different circulating sources are con
Externí odkaz:
https://doaj.org/article/48faa74e174449ca9e2519f7add9c255
Autor:
Lea M Beaulieu, Lauren Clancy, Kahraman Tanriverdi, Emelia J Benjamin, Carolyn D Kramer, Ellen O Weinberg, Xianbao He, Samrawit Mekasha, Eric Mick, Robin R Ingalls, Caroline A Genco, Jane E Freedman
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131688 (2015)
Diverse and multi-factorial processes contribute to the progression of cardiovascular disease. These processes affect cells involved in the development of this disease in varying ways, ultimately leading to atherothrombosis. The goal of our study was
Externí odkaz:
https://doaj.org/article/03a1693fba2946d0abb31ea1dbc220c3
Autor:
Hannah Karlin, Meera Sooda, Martin Larson, Jian Rong, Tianxiao Huan, Michelle M. J. Mens, Frank J. A. van Rooij, M. Arfan Ikram, Paul Courchesne, Jane E. Freedman, Roby Joehanes, Gregory P. Mueller, Maryam Kavousi, Mohsen Ghanbari, Daniel Levy
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 12 (2024)
Background Extracellular microRNAs (miRNAs) are a class of noncoding RNAs that remain stable in the extracellular milieu, where they contribute to various physiological and pathological processes by facilitating intercellular signaling. Previous stud
Externí odkaz:
https://doaj.org/article/e66624d074dc42bb91bda8fc2daebc56
Autor:
Jane E Freedman, Bahadir Ercan, Kristine M Morin, Ching-Ti Liu, Lulufer Tamer, Lokman Ayaz, Mehmet Kanadasi, Dilek Cicek, Ali Ihsan Seyhan, Rabia Eker Akilli, Celalettin Camci, Beyhan Cengiz, Serdar Oztuzcu, Kahraman Tanriverdi
Publikováno v:
F1000Research, Vol 1 (2012)
Background: MicroRNAs (miRNAs) are small RNAs that regulate gene expression by suppressing protein translation and may influence RNA expression. MicroRNAs are detected in extracellular locations such as plasma; however, the extent of miRNA expression
Externí odkaz:
https://doaj.org/article/2b9bbcd42fdc4a3299a6ca3d52e81f81
Autor:
Ravi V. Shah, Shih‐Jen Hwang, Venkatesh L. Murthy, Shilin Zhao, Kahraman Tanriverdi, Priya Gajjar, Kevin Duarte, Mark Schoenike, Robyn Farrell, Liana C. Brooks, Deepa M. Gopal, Jennifer E. Ho, Nicholas Girerd, Ramachandran S. Vasan, Daniel Levy, Jane E. Freedman, Gregory D. Lewis, Matthew Nayor
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 21 (2023)
Background While exercise impairments are central to symptoms and diagnosis of heart failure with preserved ejection fraction (HFpEF), prior studies of HFpEF biomarkers have mostly focused on resting phenotypes. We combined precise exercise phenotype
Externí odkaz:
https://doaj.org/article/2306c9218f714b4c81c636939db51d48
Autor:
Fulya Ekiz Kanik, Iris Celebi, Derin Sevenler, Kahraman Tanriverdi, Nese Lortlar Ünlü, Jane E. Freedman, M. Selim Ünlü
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract MicroRNAs (miRNAs) are a family of noncoding, functional RNAs. With recent developments in molecular biology, miRNA detection has attracted significant interest, as hundreds of miRNAs and their expression levels have shown to be linked to va
Externí odkaz:
https://doaj.org/article/2160c8073dd34992840e4382ef7a1d93
Autor:
Tianxiao Huan, Michael Mendelson, Roby Joehanes, Chen Yao, Chunyu Liu, Ci Song, Anindya Bhattacharya, Jian Rong, Kahraman Tanriverdi, Joshua Keefe, Joanne M. Murabito, Paul Courchesne, Martin G. Larson, Jane E. Freedman, Daniel Levy
Publikováno v:
Epigenetics, Vol 15, Iss 1-2, Pp 183-198 (2020)
DNA methylation (DNAm) and microRNAs (miRNAs) have been implicated in a wide-range of human diseases. While often studied in isolation, DNAm and miRNAs are not independent. We analyzed associations of expression of 283 miRNAs with DNAm at >400K CpG s
Externí odkaz:
https://doaj.org/article/ac5fe20ffd344db3b731af4b904a3a44