Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Jane E Bourke"'
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122069 (2015)
The bacterial endotoxin, lipopolysaccharide (LPS) has been associated with occupational airway diseases with asthma-like symptoms and in acute exacerbations of COPD. The direct and indirect effects of LPS on small airway reactivity have not been full
Externí odkaz:
https://doaj.org/article/ada20f28e2ff4b1aa7f89700013fa3f9
Autor:
Chantal Donovan, Simon G Royce, James Esposito, Jenny Tran, Zaridatul Aini Ibrahim, Mimi L K Tang, Simon Bailey, Jane E Bourke
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74101 (2013)
The relative contributions of large and small airways to hyperresponsiveness in asthma have yet to be fully assessed. This study used a mouse model of chronic allergic airways disease to induce inflammation and remodelling and determine whether in vi
Externí odkaz:
https://doaj.org/article/1edfeed6c9024142b6e69aacf349720e
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Precision cut lung slices (PCLS) have emerged as powerful experimental tools for respiratory research. Pioneering studies using mouse PCLS to visualize intrapulmonary airway contractility have been extended to pulmonary arteries and for assessment of
Externí odkaz:
https://doaj.org/article/af5f52d2455c4d8d9e7749ed6f6a6164
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
SARS-CoV-2 infection causes a variety of physiological responses in the lung, and understanding how the expression of SARS-CoV-2 receptor, angiotensin-converting enzyme 2 (ACE2), and its proteolytic activator, transmembrane serine protease 2 (TMPRSS2
Externí odkaz:
https://doaj.org/article/609ed4e6a10842b2948bcb8feeeccfd1
Autor:
Elys A. Green, Steven P. Garrick, Briana Peterson, Philip J. Berger, Robert Galinsky, Rod W. Hunt, Steven X. Cho, Jane E. Bourke, Marcel F. Nold, Claudia A. Nold-Petry
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2795 (2023)
Preterm birth is a major contributor to neonatal morbidity and mortality. Complications of prematurity such as bronchopulmonary dysplasia (BPD, affecting the lung), pulmonary hypertension associated with BPD (BPD-PH, heart), white matter injury (WMI,
Externí odkaz:
https://doaj.org/article/385138401cc346378560e4dd652fe312
Autor:
Christine B. Bui, Magdalena Kolodziej, Emma Lamanna, Kirstin Elgass, Arvind Sehgal, Ina Rudloff, Daryl O. Schwenke, Hirotsugu Tsuchimochi, Maurice A. G. M. Kroon, Steven X. Cho, Anton Maksimenko, Marian Cholewa, Philip J. Berger, Morag J. Young, Jane E. Bourke, James T. Pearson, Marcel F. Nold, Claudia A. Nold-Petry
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Pulmonary hypertension secondary to bronchopulmonary dysplasia (BPD-PH) represents a major complication of BPD in extremely preterm infants for which there are currently no safe and effective interventions. The abundance of interleukin-1 (IL-1) is st
Externí odkaz:
https://doaj.org/article/4cf373f5de034ebeae37df5fe137e7df
Cardioprotective Actions of the Annexin-A1 N-Terminal Peptide, Ac2-26, Against Myocardial Infarction
Autor:
Cheng Xue Qin, Sarah Rosli, Minh Deo, Nga Cao, Jesse Walsh, Mitchel Tate, Amy E. Alexander, Daniel Donner, Duncan Horlock, Renming Li, Helen Kiriazis, Man K. S. Lee, Jane E. Bourke, Yuan Yang, Andrew J. Murphy, Xiao-Jun Du, Xiao Ming Gao, Rebecca H. Ritchie
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
The anti-inflammatory, pro-resolving annexin-A1 protein acts as an endogenous brake against exaggerated cardiac necrosis, inflammation, and fibrosis following myocardial infarction (MI) in vivo. Little is known, however, regarding the cardioprotectiv
Externí odkaz:
https://doaj.org/article/f7ef1d1ab6214a6981118ab16deba530
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d51ee629457ea7ee0aa4c25a79f52c3
https://doi.org/10.1165/rcmb.2021-0544oc
https://doi.org/10.1165/rcmb.2021-0544oc
Autor:
Jane E. Bourke, Jiayin Diao, Karen J. Gregory, Ben Capuano, Aaron DeBono, Katie Leach, Tracy M. Josephs
Publikováno v:
ACS Pharmacol Transl Sci
[Image: see text] The CaSR is a class C G protein-coupled receptor (GPCR) that acts as a multimodal chemosensor to maintain diverse homeostatic functions. The CaSR is a clinical therapeutic target in hyperparathyroidism and has emerged as a putative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::490e43c525fe6dc6f3ec03a60ec4e3cc
https://doi.org/10.1021/acsptsci.1c00046
https://doi.org/10.1021/acsptsci.1c00046
Publikováno v:
Airway cell biology and immunopathology.
1. Precision cut lung slices (PCLS) offer a unique integrated experimental platform for investigating both inflammatory and immune responses to viral infection. 2. This study aimed to develop a protocol for robust infection of PCLS ex vivo with influ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4ef24d672e66b19d2de65f798b4650e
https://doi.org/10.1183/13993003.congress-2021.pa3691
https://doi.org/10.1183/13993003.congress-2021.pa3691