Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jane Criswell"'
Autor:
G. Timothy Bowden, David S. Alberts, Zigang Dong, Ann M. Bode, Chengcheng Hu, Kathylynn Saboda, Clara Curiel-Lewandrowski, Steven P. Stratton, Jesse E. Dickinson, Janine Einspahr, Valerie S. Calvert, Emanuel F. Petricoin, Christy Barber, Zhonglin Liu, Erik R. Olson, Karen Blohm-Mangone, Jane Criswell, Jaroslav Janda, Sally E. Dickinson
The PI3Kinase/Akt/mTOR pathway has important roles in cancer development for multiple tumor types, including UV-induced nonmelanoma skin cancer. Immunosuppressed populations are at increased risk of aggressive cutaneous squamous cell carcinoma (SCC).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6df9fccf19b0cff22118b6a5f393eba6
https://doi.org/10.1158/1940-6207.c.6547411.v1
https://doi.org/10.1158/1940-6207.c.6547411.v1
Autor:
G. Timothy Bowden, David S. Alberts, Zigang Dong, Ann M. Bode, Chengcheng Hu, Kathylynn Saboda, Clara Curiel-Lewandrowski, Steven P. Stratton, Jesse E. Dickinson, Janine Einspahr, Valerie S. Calvert, Emanuel F. Petricoin, Christy Barber, Zhonglin Liu, Erik R. Olson, Karen Blohm-Mangone, Jane Criswell, Jaroslav Janda, Sally E. Dickinson
Schema representing UV-induced signaling, rapamycin and PHT-427-regulated pathways in keratinocytes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::301db922cffaaf2f15b06bc176fc97a0
https://doi.org/10.1158/1940-6207.22534219.v1
https://doi.org/10.1158/1940-6207.22534219.v1
Autor:
David S. Alberts, Ana Casanova, Elizabeth T. Jacobs, G. Tim Bowden, Kathylynn Saboda, Zigang Dong, P. Jane Criswell, Sally E. Dickinson, Simon J. Cooper, Jack Zhang, Erik R. Olson, Tania Melton, Chengcheng Hu
Publikováno v:
Molecular Carcinogenesis. 50:469-478
UVB irradiation of epidermal keratinocytes results in the activation of the p38 mitogen-activated protein kinase (MAPK) pathway and subsequently activator protein-1 (AP-1) transcription factor activation and cyclooxygenase-2 (COX-2) expression. AP-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34d7c73a772605b48eeea0ad688ed0df
https://doi.org/10.1002/mc.20734
https://doi.org/10.1002/mc.20734
Autor:
Kathylynn Saboda, G. Timothy Bowden, Jadrian J. Rusche, Sally E. Dickinson, David S. Alberts, Jack Zhang, Chengcheng Hu, P. Jane Criswell, Erik R. Olson, Zagong Dong
Publikováno v:
Cancer Research. 73:1077-1077
Phosphoinositide-3 Kinase (PI3-Kinase) is an upstream regulator of cellular proliferation and anti-apoptotic signaling that has been implicated in cancer induction in many tissues, including skin. Pharmacological inhibition of PI3-Kinase is effective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::643ebfd18e647f99bb822d78a3f2b02f
https://doi.org/10.1158/1538-7445.am2013-1077
https://doi.org/10.1158/1538-7445.am2013-1077