Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jane C. Lee"'
Publikováno v:
Frontiers in Physiology, Vol 5 (2014)
Significant progress has been made in the last decade in the development of optogenetic effectors and sensors that can be deployed to understand complex biological signaling in mammals at a molecular level, without disrupting the distributed, lineage
Externí odkaz:
https://doaj.org/article/5fbbe4943cfd439bb14d6847a05184a4
Autor:
Frank K Lee, Jane C Lee, Bo Shui, Shaun Reining, Megan Jibilian, David M Small, Jason S Jones, Nathaniel H Allan-Rahill, Michael RE Lamont, Megan A Rizzo, Sendoa Tajada, Manuel F Navedo, Luis Fernando Santana, Nozomi Nishimura, Michael I Kotlikoff
Publikováno v:
eLife, Vol 10 (2021)
Optogenetic effectors and sensors provide a novel real-time window into complex physiological processes, enabling determination of molecular signaling processes within functioning cellular networks. However, the combination of these optical tools in
Externí odkaz:
https://doaj.org/article/1b8cb82950fd45838080d740449051eb
Autor:
Frank K. Lee, Yen Lin Chen, Michael I. Kotlikoff, Thomas M Baker, Swapnil K. Sonkusare, Jane C. Lee, Bo Shui, Petr Tvrdik
Publikováno v:
J Vasc Res
Introduction: Studies in Cx40-GCaMP2 mice, which express calcium biosensor GCaMP2 in the endothelium under connexin 40 promoter, have identified the unique properties of endothelial calcium signals. However, Cx40-GCaMP2 mouse is associated with a nar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68aa0eab2f4e903580e7b3e043f0a4b4
https://doi.org/10.1159/000514210
https://doi.org/10.1159/000514210
Autor:
Michael I. Kotlikoff, Shaun Reining, Manuel F. Navedo, Jason S. Jones, David M. Small, Megan A. Rizzo, Bo Shui, Nozomi Nishimura, Nathaniel H. Allan-Rahill, Megan Jibilian, Luis Fernando Santana, Sendoa Tajada, Michael R. E. Lamont, Frank K. Lee, Jane C. Lee
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Rationale: Optogenetic effectors and sensors provide a novel real-time window into complex physiological processes, enabling determination of molecular signaling processes within functioning cellular networks. The effective combination of these optic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9644e2560d7cacf543df9470f0f62595
https://escholarship.org/uc/item/0rx691mc
https://escholarship.org/uc/item/0rx691mc
Autor:
Mark T. Nelson, Bo Shui, Thomas A Longden, Amreen Mughal, Frank K. Lee, Jane C. Lee, Michael I. Kotlikoff, Gabriele M. König, David C. Hill-Eubanks, Shaun Reining, Evi Kostenis, Osama F. Harraz, Grant W. Hennig
Publikováno v:
Science Advances
Sci Adv
Sci Adv
Brain capillary calcium signaling controls blood flow.
Healthy brain function depends on the finely tuned spatial and temporal delivery of blood-borne nutrients to active neurons via the vast, dense capillary network. Here, using in vivo imaging
Healthy brain function depends on the finely tuned spatial and temporal delivery of blood-borne nutrients to active neurons via the vast, dense capillary network. Here, using in vivo imaging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8b72739a5edeb2cc2a9ee7266afdab
http://europepmc.org/articles/PMC8294755
http://europepmc.org/articles/PMC8294755
Autor:
Jesse Moore, Shaun Reining, Michael I. Kotlikoff, Bo Shui, Mark T. Nelson, Zachary D. Miller, Frank K. Lee, Nuria Villalba, Adrian D. Bonev, Kalev Freeman, Daniel M. Collier, Jane C. Lee, Adrian M. Sackheim
Publikováno v:
Am J Physiol Heart Circ Physiol
Histone proteins are elevated in the circulation after traumatic injury owing to cellular lysis and release from neutrophils. Elevated circulating histones in trauma contribute to coagulopathy and mortality through a mechanism suspected to involve en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f38894a4176e752f076d0ee5c2cdd72b
https://doi.org/10.1152/ajpheart.00655.2018
https://doi.org/10.1152/ajpheart.00655.2018
Autor:
Mark T. Nelson, Nikolaos M. Tsoukias, Michael I. Kotlikoff, Frank K. Lee, Bo Shui, Albert L. Gonzales, Jane C. Lee, Arash Moshkforoush, David C. Hill-Eubanks, Nicholas R. Klug
Publikováno v:
PNAS
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
The essential function of the circulatory system is to continuously and efficiently supply the O(2) and nutrients necessary to meet the metabolic demands of every cell in the body, a function in which vast capillary networks play a key role. Capillar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f88f7a59d17ac2f1d655d7470acd3375
Autor:
Xianhua Wang, Frank K. Lee, Robert Doran, Tao Sun, Bo Shui, Heping Cheng, Michael I. Kotlikoff, Qing Sunny Shen, Jane C. Lee, Wenwen Li, Hui Liu, Shaun Reining, Wei Zhao, Cuiwei Sun, Zhiqian Zhang
Publikováno v:
Cell Death and Disease, Vol 10, Iss 6, Pp 1-13 (2019)
Ca2+ oscillation is a system-level property of the cellular Ca2+-handling machinery and encodes diverse physiological and pathological signals. The present study tests the hypothesis that Ca2+ oscillations play a vital role in maintaining the stemnes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5f3ee14b1c38427abeaaf42801f9b26
https://doi.org/10.1038/s41419-019-1613-2
https://doi.org/10.1038/s41419-019-1613-2
Autor:
Jane C. Lee, Bo Liu, Frank K. Lee, Sheyda Azimi, Ian P. Hall, Michael I. Kotlikoff, Suzanne Miller, Amanda P. Henry, Ian Sayers, Kelly Probert
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0221899 (2019)
PLoS ONE
PLoS ONE
IntroductionGenome-Wide Association Studies suggest glutathione S transferase C terminal domain (GSTCD) may play a role in development of Chronic Obstructive Pulmonary Disease. We aimed to define the potential role of GSTCD in airway inflammation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::848f042548fcacd218bfbb1c58397f0d
https://doaj.org/article/ec8d27b6cfac44e880f6ab3ddd84cfa7
https://doaj.org/article/ec8d27b6cfac44e880f6ab3ddd84cfa7
Autor:
Jane C. Lee, Amy Turner, Steven A. Moore, Hajime Kusano, Kevin P. Campbell, Huy A. Nguyen, Toshinori Hoshi, Steve Westra, Susan E. Ross-Barta, Adam P. Ostendorf, Jakob S. Satz, Rolf Turk, Shangwei Hou
Publikováno v:
The Journal of Neuroscience. 30:14560-14572
Cobblestone (type II) lissencephaly and mental retardation are characteristic features of a subset of congenital muscular dystrophies that include Walker–Warburg syndrome, muscle-eye-brain disease, and Fukuyama-type congenital muscular dystrophy. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d7e2834e40739dc024ad3e590047692
https://doi.org/10.1523/jneurosci.3247-10.2010
https://doi.org/10.1523/jneurosci.3247-10.2010