Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Jane C. Deng"'
Autor:
Judy Chen, Jane C. Deng, Rachel L. Zemans, Karim Bahmed, Beata Kosmider, Min Zhang, Marc Peters-Golden, Daniel R. Goldstein
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Ageing has been associated with impaired function of alveolar macrophages and increased susceptibility, mortality and complications as a result of viral infection. Here, the authors show that prostaglandin E2 is one of the factors responsible for imp
Externí odkaz:
https://doaj.org/article/3c42d5d95c814302adbeaa6e8a8f666d
Publikováno v:
Biomedicines, Vol 11, Iss 8, p 2252 (2023)
Neutrophils are an essential cellular component of innate immunity and control bacterial infections through a combination of intracellular and extracellular killing methods. Although the importance of neutrophils has been established, the exact metho
Externí odkaz:
https://doaj.org/article/562cdb8729aa4f588cf270eaed165256
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
BackgroundLung inflammation, neutrophil infiltration, and pulmonary vascular leakage are pathological hallmarks of acute respiratory distress syndrome (ARDS) which can lethally complicate respiratory viral infections. Despite similar comorbidities, h
Externí odkaz:
https://doaj.org/article/e3b05df0f75146c5b2373ec3f21a22bc
Autor:
Jintao Xu, Bing He, Kyle Carver, Debora Vanheyningen, Brian Parkin, Lana X. Garmire, Michal A. Olszewski, Jane C. Deng
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Severe respiratory viral infections, including SARS-CoV-2, have resulted in high mortality rates despite corticosteroids and other immunomodulatory therapies. Despite recognition of the pathogenic role of neutrophils, in-depth analyses of this cell p
Externí odkaz:
https://doaj.org/article/fd2f2bc0be214cf0b370425530462fc4
Autor:
Kathryn H. Melamed, Justin Williams, Xiaoyan Wang, Scott Hu, Christopher Nguyen, Jing Cui, Jane C. Deng
Publikováno v:
Therapeutic Advances in Respiratory Disease, Vol 14 (2020)
Background: Respiratory viral infections, particularly influenza, are known to cause significant morbidity and mortality, often due to secondary infections. Our aim was to comparatively analyze the incidence, epidemiology, and outcomes of secondary p
Externí odkaz:
https://doaj.org/article/545ba4b8ee8f4d9296ee76830cd833f4
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Influenza and other respiratory viral infections are the most common type of acute respiratory infection. Viral infections predispose patients to secondary bacterial infections, which often have a more severe clinical course. The mechanisms underlyin
Externí odkaz:
https://doaj.org/article/144486bc46074b8daa0414d0679b0b4f
Autor:
Colleen L. Channick, Guang-Shing Cheng, Van K. Holden, Jamie L. Garfield, Sahil Patel, Başak Çoruh, Josalyn L. Cho, Erin R Camac, Elizabeth Guzman, Scott Oh, Tisha Wang, Krishna M. Sundar, Ngoc-Tram Ha, Margaret M. Hayes, Janelle V. Baptiste, Jose De Cardenas, Jakob I. McSparron, Max T Wayne, Oisin A. O'Corragain, Codi Fitzgerald, Garth Garrison, Jane C. Deng
Publikováno v:
ATS Scholar
ATS scholar, vol 2, iss 3
ATS scholar, vol 2, iss 3
The American Thoracic Society Core Curriculum updates clinicians annually in adult and pediatric pulmonary disease, medical critical care, and sleep medicine at the annual international conference. The 2021 Pulmonary Core Curriculum focuses on lung c
Publikováno v:
Trends in molecular medicine. 28(12)
Aging leads to a gradual dysregulation of immune functions, one consequence of which is reduced vaccine efficacy. In this review, we discuss several key contributing factors to the age-related decline in vaccine efficacy, such as alterations within t
Autor:
Matthew K. Hensley, Jane C. Deng
Publikováno v:
Chest. 158:e279-e282
Case Presentation A 35-year-old veteran presented at our clinic with insidious dyspnea on exertion, nonspecific chest pain, and intermittent rash. The patient reported the development of dyspnea over 6 to 8 weeks. He had been physically active before