Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jane C F, Chang"'
Autor:
Jane C F, Chang, Paul, Ciaccio, Patricia, Schroeder, Lindsay, Wright, Russell, Westwood, Anna-Lena, Berg
Publikováno v:
Journal of Toxicologic Pathology
AZD3783, a cationic amphiphilic drug and a potent inhibitor of the 5-hydroxytryptamine (5-HT1B) receptor, was explored as a potential treatment for depression. To support clinical trials, repeat dose toxicity studies in rats and dogs were conducted.
Publikováno v:
Fundamental and Applied Toxicology. 19:307-314
The purpose of this study was to determine the chronic toxicity of methidathion, an organophosphate insecticide, in dogs. Groups of beagle dogs, four/sex/dose, were fed methidathion at constant dietary concentrations of 0, 0.5, 2, 4, 40, or 140 ppm f