Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jane Boesen"'
Autor:
Per Nørgaard, Jing Su, Jane Boesen Frantzen, Zhiru Yang, Anne Bugge, Chih-Chuan Chang, Linu M. John, Anna Secher, Zhenhua He, Haisun Zhu, Tao Huang, Wei Yang, Kristian Tage Hansen, Xiaoai Wu, Xiang Gao, Sarah J Paulsen, Sebastian Beck Jørgensen, Jacob Jeppesen, Zhe Sun, Linda Yang, Haibin Chen, Bing Shan, Xun Li, Karin Hultman, Jishu Wang, Søren Berg Padkjær, Dennis Madsen
Publikováno v:
Nature Medicine. 23:1158-1166
Growth differentiation factor 15 (GDF15; also known as MIC-1) is a divergent member of the TGF-β superfamily and is associated with body-weight regulation in humans and rodents. However, the cognate receptor of GDF15 is unknown. Here we show that GD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df7309da29b5ef10acefc642a3c77d83
https://doi.org/10.1038/nm.4394
https://doi.org/10.1038/nm.4394
Autor:
Günther H.J. Peters, Kasper Damgaard Tidemand, Pernille Harris, Hans Erik Mølager Christensen, Niclas Hoeck, Jane Boesen
Publikováno v:
Tidemand, K D, Christensen, H E M, Hoeck, N, Harris, P, Boesen, J & Peters, G H J 2016, ' Stabilization of Tryptophan Hydroxylase 2 by L-Phenylalanine Induced Dimerization ', F E B S Open Bio, vol. 6, no. 10, pp. 987-999 . https://doi.org/10.1002/2211-5463.12100
FEBS Open Bio
FEBS Open Bio
Tryptophan hydroxylase 2 (TPH2) catalyses the initial and rate-limiting step in the biosynthesis of serotonin, which is associated with a variety of disorders such as depression, obsessive compulsive disorder, and schizophrenia. Full-length TPH2 is p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1988c0e3f5ef874ee4035fa2d194875
https://orbit.dtu.dk/en/publications/fab2fb05-4db6-4ed0-9bfd-0dd3381553ac
https://orbit.dtu.dk/en/publications/fab2fb05-4db6-4ed0-9bfd-0dd3381553ac
Publikováno v:
Journal of Inorganic Biochemistry. 104:136-145
Insight into the nature of oxygen activation in tryptophan hydroxylase has been obtained from density functional computations. Conformations of O(2)-bound intermediates have been studied with oxygen trans to glutamate and histidine, respectively. An
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de84bfcda3919a55bcd78299af935fdc
https://doi.org/10.1016/j.jinorgbio.2009.10.010
https://doi.org/10.1016/j.jinorgbio.2009.10.010
Autor:
Jane Boesen, Trine V. Vendelboe, Pernille Harris, Astrid Munch, Hans Erik Mølager Christensen, Michael Ericsson Skovbo Nielsen, Charlotte Rode Petersen
Publikováno v:
Protein Expression and Purification. 57:116-126
Tryptophan hydroxylase (TPH) [EC 1.14.16.4] catalyzes the conversion of tryptophan to 5-hydroxytryptophan, which is the first and rate-determining step in the biosynthesis of the neurotransmitter serotonin. We have expressed the catalytic domain of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc2407983f04240967be9a3d541c948
https://doi.org/10.1016/j.pep.2007.10.016
https://doi.org/10.1016/j.pep.2007.10.016
Akademický článek
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Autor:
Pernille Efferbach Karlsen, Jane Boesen, Hans Erik Mølager Christensen, Michael Skovbo Windahl
Publikováno v:
The protein journal. 28(9-10)
Tryptophan hydroxylase exists in two isoforms: Isoform 1 catalyses the first and rate-limiting step in the synthesis of serotonin in the peripheral parts of the body while isoform 2 catalyses this step in the brain. The catalytic domains of human try
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfec618e8412dc4df7e7b733540332ee
https://pubmed.ncbi.nlm.nih.gov/19816759
https://pubmed.ncbi.nlm.nih.gov/19816759
Autor:
Tidemand, Kasper D., Christensen, Hans E. M., Hoeck, Niclas, Harris, Pernille, Boesen, Jane, Peters, Günther H.
Publikováno v:
FEBS Open Bio; Oct2016, Vol. 6 Issue 10, p987-999, 13p
Autor:
Karen Risager
This book presents a new and comprehensive framework for the analysis of representations of culture, society and the world in textbooks for foreign and second language learning. The framework is transferable to other kinds of learning materials and t