Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jane Barraclough"'
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 9, Iss 9, Pp 745-754 (2007)
Increases in the levels and/or activity of nonreceptor tyrosine kinases c-Src and c-Yes are often associated with colorectal carcinogenesis. The physiological consequences of increased c-Yes activity during the early and late stages of tumorigenesis,
Externí odkaz:
https://doaj.org/article/97e62d1d61d34a5e86f7347da5a3bfd6
Autor:
Arkadiusz Welman, Christopher Cawthome, Lourdes Ponce-Perez, Jane Barraclough, Sarah Danson, Stephen Murray, Jeff Cummings, Terry D. Allen, Caroline Dive
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 8, Iss 11, Pp 905-916 (2006)
The levels and activity of c-Src in colorectal cancer cells increase steadily during the course of colorectal carcinogenesis and are most highly elevated in advanced metastatic disease. However, the effects of increases in c-Src activity on the proli
Externí odkaz:
https://doaj.org/article/454c53c857964bff841b90da6feb0ba8
Autor:
Elizabeth A. Musgrove, Cristin G. Print, Robert L. Sutherland, Rob I. Nicholson, Julia M. Gee, Lance D. Miller, Michael A. Black, Christine S. Lee, Jane Barraclough, Andrew Stone, Marijke N. Boersma, Anita Muthukaruppan, Jian Kang, C. Marcelo Sergio, C. Elizabeth Caldon
PDF file, 41KB, Supplementary Figure 3: Effect of overexpression of cyclins E1 and E2 on antiestrogen-induced growth arrest. T-47D cells overexpressing cyclin E1, cyclin E2 or vector control were treated with fulvestrant or vehicle. Densitometry of W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b56fdd7b8ef1692d5996ff085c1d435
https://doi.org/10.1158/1535-7163.22496367
https://doi.org/10.1158/1535-7163.22496367
Autor:
Elizabeth A. Musgrove, Cristin G. Print, Robert L. Sutherland, Rob I. Nicholson, Julia M. Gee, Lance D. Miller, Michael A. Black, Christine S. Lee, Jane Barraclough, Andrew Stone, Marijke N. Boersma, Anita Muthukaruppan, Jian Kang, C. Marcelo Sergio, C. Elizabeth Caldon
Cyclin E2, but not cyclin E1, is included in several gene signatures that predict disease progression in either tamoxifen-resistant or metastatic breast cancer. We therefore examined the role of cyclin E2 in antiestrogen resistance in vitro and its p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c5f42b0999852523b1d14a21695d2c
https://doi.org/10.1158/1535-7163.c.6535245.v1
https://doi.org/10.1158/1535-7163.c.6535245.v1
Autor:
Elizabeth A. Musgrove, Cristin G. Print, Robert L. Sutherland, Rob I. Nicholson, Julia M. Gee, Lance D. Miller, Michael A. Black, Christine S. Lee, Jane Barraclough, Andrew Stone, Marijke N. Boersma, Anita Muthukaruppan, Jian Kang, C. Marcelo Sergio, C. Elizabeth Caldon
PDF file, 56KB.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c981343b4d6da4a0978ea17836b2e6
https://doi.org/10.1158/1535-7163.22496364.v1
https://doi.org/10.1158/1535-7163.22496364.v1
Autor:
Elizabeth A. Musgrove, Cristin G. Print, Robert L. Sutherland, Rob I. Nicholson, Julia M. Gee, Lance D. Miller, Michael A. Black, Christine S. Lee, Jane Barraclough, Andrew Stone, Marijke N. Boersma, Anita Muthukaruppan, Jian Kang, C. Marcelo Sergio, C. Elizabeth Caldon
PDF file, 929KB, Supplementary Figure 1: Cyclin E2 association with breast cancer subtype, grade, and outcome. A: Relationship between a second cyclin E2 probeset and breast cancer subtype, or histological grade. Box: upper and lower quartiles; divid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bd6eafb562fc2e57bc31afce5e5f10f
https://doi.org/10.1158/1535-7163.22496373.v1
https://doi.org/10.1158/1535-7163.22496373.v1
Autor:
Elizabeth A. Musgrove, Cristin G. Print, Robert L. Sutherland, Rob I. Nicholson, Julia M. Gee, Lance D. Miller, Michael A. Black, Christine S. Lee, Jane Barraclough, Andrew Stone, Marijke N. Boersma, Anita Muthukaruppan, Jian Kang, C. Marcelo Sergio, C. Elizabeth Caldon
PDF file, 78KB, Supplementary Figure 2: Deregulation of cyclin E in tamoxifen-resistant cells. MCF-7C and TAMR cells were treated with vehicle, OH-Tam (100 nM) or fulvestrant (10 nM). A: S phase percentage derived from flow cytometry of propidium iod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c9397aebc27c9006f875c409cc284d3
https://doi.org/10.1158/1535-7163.22496370.v1
https://doi.org/10.1158/1535-7163.22496370.v1
Autor:
Crispin G. Print, Robert Ian Nicholson, Christine Lee, Robert L. Sutherland, Andrew Stone, Michael A. Black, Jian Kang, C. Elizabeth Caldon, Lance D. Miller, Anita Muthukaruppan, C. Marcelo Sergio, Julia Margaret Wendy Gee, Marikje N. Boersma, Elizabeth A. Musgrove, Jane Barraclough
Publikováno v:
Molecular Cancer Therapeutics. 11:1488-1499
Cyclin E2, but not cyclin E1, is included in several gene signatures that predict disease progression in either tamoxifen-resistant or metastatic breast cancer. We therefore examined the role of cyclin E2 in antiestrogen resistance in vitro and its p
Publikováno v:
Nature Protocols. 1:803-811
Tet-on cell lines engineered to stably express doxycycline (Dox)-regulated reverse transcriptional transactivator (rtTA) have many applications in biomedical research and biotechnology. Unfortunately, construction and maintenance of such cells often
Autor:
Gareth J. Griffiths, Jane Barraclough, Arkadiusz Welman, Christopher Cawthorne, Judith C. Williams, Ian J. Stratford, Caroline Dive, Nigel K Smith, Rachel L. Cowen
Publikováno v:
Journal of Cellular Biochemistry. 94:1148-1162
Validation of targets for cancer drug discovery requires robust experimental models. Systems based on inducible gene expression are well suited to this purpose but are difficult to establish in several epithelial cell types. Using the recently discov