Zobrazeno 1 - 10
of 695
pro vyhledávání: '"Jane B. Lian"'
Autor:
Jonathan A. R. Gordon, Coralee E. Tye, Bodhisattwa Banerjee, Prachi N. Ghule, Andre J. van Wijnen, Fleur S. Kabala, Natalie A. Page, Michelle M. Falcone, Janet L. Stein, Gary S. Stein, Jane B. Lian
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract The skeleton forms from multipotent human mesenchymal stem cells (hMSCs) competent to commit to specific lineages. Long noncoding RNAs (lncRNAs) have been identified as key epigenetic regulators of tissue development. However, regulation of
Externí odkaz:
https://doaj.org/article/22d7cc53663c45a996950aef704e675e
Autor:
Amel Dudakovic, Sofia Jerez, Padmini J. Deosthale, Janet M. Denbeigh, Christopher R. Paradise, Martina Gluscevic, Pengfei Zan, Dana L. Begun, Emily T. Camilleri, Oksana Pichurin, Farzaneh Khani, Roman Thaler, Jane B. Lian, Gary S. Stein, Jennifer J. Westendorf, Lilian I. Plotkin, Andre J. van Wijnen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract High-throughput microRNA sequencing was performed during differentiation of MC3T3-E1 osteoblasts to develop working hypotheses for specific microRNAs that control osteogenesis. The expression data show that miR-101a, which targets the mRNAs
Externí odkaz:
https://doaj.org/article/f5c778c9a9e84a5d9acbf3c478897543
Autor:
Coralee E. Tye, Prachi N. Ghule, Jonathan A. R. Gordon, Fleur S. Kabala, Natalie A. Page, Michelle M. Falcone, Kirsten M. Tracy, Andre J. van Wijnen, Janet L. Stein, Jane B. Lian, Gary S. Stein
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Bone formation requires osteogenic differentiation of multipotent mesenchymal stromal cells (MSCs) and lineage progression of committed osteoblast precursors. Osteogenic phenotype commitment is epigenetically controlled by genomic (chromatin
Externí odkaz:
https://doaj.org/article/cb869d076f7b42c0a921afee30acdf08
Autor:
Alex F Thompson, Patrick R Blackburn, Noah S Arons, Sarah N Stevens, Dusica Babovic-Vuksanovic, Jane B Lian, Eric W Klee, Jason Stumpff
Publikováno v:
eLife, Vol 11 (2022)
The chromokinesin KIF22 generates forces that contribute to mitotic chromosome congression and alignment. Mutations in the α2 helix of the motor domain of KIF22 have been identified in patients with abnormal skeletal development, and we report the i
Externí odkaz:
https://doaj.org/article/8723f0c9edc84db2b8e75bfe755aa234
Autor:
Terri L Messier, Joseph R Boyd, Jonathan A R Gordon, Coralee E Tye, Natalie A Page, Rabail H Toor, Sayyed K Zaidi, Barry S Komm, Seth Frietze, Janet L Stein, Jane B Lian, Gary S Stein
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0271725 (2022)
Selective estrogen receptor modulators (SERMs), including the SERM/SERD bazedoxifene (BZA), are used to treat postmenopausal osteoporosis and may reduce breast cancer (BCa) risk. One of the most persistent unresolved questions regarding menopausal ho
Externí odkaz:
https://doaj.org/article/23747e72e03144299f6791559e911b97
Autor:
Xiangguo Che, Xian Jin, Na Rae Park, Hee-June Kim, Hee-Soo Kyung, Hyun-Ju Kim, Jane B. Lian, Janet L. Stein, Gary S. Stein, Je-Yong Choi
Publikováno v:
Cells, Vol 12, Iss 7, p 1064 (2023)
TGF-β signaling is a vital regulator for maintaining articular cartilage homeostasis. Runx transcription factors, downstream targets of TGF-β signaling, have been studied in the context of osteoarthritis (OA). Although Runx partner core binding fac
Externí odkaz:
https://doaj.org/article/1b6314ddf1de49f9919e18a88f0a2261
Autor:
Andrew J. Fritz, Prachi N. Ghule, Rabail Toor, Louis Dillac, Jonah Perelman, Joseph Boyd, Jane B. Lian, Johnathan A. R. Gordon, Seth Frietze, Andre Van Wijnen, Janet L. Stein, Gary S. Stein
Publikováno v:
Critical Reviews in Eukaryotic Gene Expression. 33:85-97
Higher-order genomic organization supports the activation of histone genes in response to cell cycle regulatory cues that epigenetically mediates stringent control of transcription at the G1/S-phase transition. Histone locus bodies (HLBs) are dynamic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35689381506c0b60a31eab7d0c7c0b81
https://doi.org/10.1615/critreveukaryotgeneexpr.2022046190
https://doi.org/10.1615/critreveukaryotgeneexpr.2022046190
Autor:
Jane B. Lian, Gary S. Stein, Janet L. Stein, Jason Stumpff, Heidi L.H. Malaby, Prachi N. Ghule, Coralee E. Tye, Kirsten M. Tracy
Validation of expressed genes from RNA-seq.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f4b9bcec86bd3192cb3e05fcbd4cc51
https://doi.org/10.1158/1541-7786.22513584
https://doi.org/10.1158/1541-7786.22513584
Autor:
Jane B. Lian, Gary S. Stein, Janet L. Stein, Jason Stumpff, Heidi L.H. Malaby, Prachi N. Ghule, Coralee E. Tye, Kirsten M. Tracy
MANCR-depleted MDA-MB-231 cells exhibit a more normal-like expression of genes related to cell cycle processes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206252cb8a19beb6c782f0482ee450ee
https://doi.org/10.1158/1541-7786.22513581
https://doi.org/10.1158/1541-7786.22513581
Autor:
Jane B. Lian, Gary S. Stein, Janet L. Stein, Jason Stumpff, Heidi L.H. Malaby, Prachi N. Ghule, Coralee E. Tye, Kirsten M. Tracy
MANCR depletion does not affect timing of anaphase onset.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cacd35dfdfb58ba181f56f17bda3be3
https://doi.org/10.1158/1541-7786.22513578
https://doi.org/10.1158/1541-7786.22513578