Zobrazeno 1 - 10
of 1 084
pro vyhledávání: '"Jane B. Lian"'
Autor:
Jonathan A. R. Gordon, Coralee E. Tye, Bodhisattwa Banerjee, Prachi N. Ghule, Andre J. van Wijnen, Fleur S. Kabala, Natalie A. Page, Michelle M. Falcone, Janet L. Stein, Gary S. Stein, Jane B. Lian
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract The skeleton forms from multipotent human mesenchymal stem cells (hMSCs) competent to commit to specific lineages. Long noncoding RNAs (lncRNAs) have been identified as key epigenetic regulators of tissue development. However, regulation of
Externí odkaz:
https://doaj.org/article/22d7cc53663c45a996950aef704e675e
Autor:
Amel Dudakovic, Sofia Jerez, Padmini J. Deosthale, Janet M. Denbeigh, Christopher R. Paradise, Martina Gluscevic, Pengfei Zan, Dana L. Begun, Emily T. Camilleri, Oksana Pichurin, Farzaneh Khani, Roman Thaler, Jane B. Lian, Gary S. Stein, Jennifer J. Westendorf, Lilian I. Plotkin, Andre J. van Wijnen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract High-throughput microRNA sequencing was performed during differentiation of MC3T3-E1 osteoblasts to develop working hypotheses for specific microRNAs that control osteogenesis. The expression data show that miR-101a, which targets the mRNAs
Externí odkaz:
https://doaj.org/article/f5c778c9a9e84a5d9acbf3c478897543
Autor:
Coralee E. Tye, Prachi N. Ghule, Jonathan A. R. Gordon, Fleur S. Kabala, Natalie A. Page, Michelle M. Falcone, Kirsten M. Tracy, Andre J. van Wijnen, Janet L. Stein, Jane B. Lian, Gary S. Stein
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Bone formation requires osteogenic differentiation of multipotent mesenchymal stromal cells (MSCs) and lineage progression of committed osteoblast precursors. Osteogenic phenotype commitment is epigenetically controlled by genomic (chromatin
Externí odkaz:
https://doaj.org/article/cb869d076f7b42c0a921afee30acdf08
Autor:
David S. Lapointe, Gary S. Stein, Andre J. Van Wijnen, Daniel W. Young, Jane B. Lian, Janet L. Stein, Eva Balint, Hicham Drissi, Caroline M. J. van der Meijden
Publikováno v:
Journal of Cellular Biochemistry. 89:862-862
Autor:
Alex F Thompson, Patrick R Blackburn, Noah S Arons, Sarah N Stevens, Dusica Babovic-Vuksanovic, Jane B Lian, Eric W Klee, Jason Stumpff
Publikováno v:
eLife, Vol 11 (2022)
The chromokinesin KIF22 generates forces that contribute to mitotic chromosome congression and alignment. Mutations in the α2 helix of the motor domain of KIF22 have been identified in patients with abnormal skeletal development, and we report the i
Externí odkaz:
https://doaj.org/article/8723f0c9edc84db2b8e75bfe755aa234
Autor:
Terri L Messier, Joseph R Boyd, Jonathan A R Gordon, Coralee E Tye, Natalie A Page, Rabail H Toor, Sayyed K Zaidi, Barry S Komm, Seth Frietze, Janet L Stein, Jane B Lian, Gary S Stein
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0271725 (2022)
Selective estrogen receptor modulators (SERMs), including the SERM/SERD bazedoxifene (BZA), are used to treat postmenopausal osteoporosis and may reduce breast cancer (BCa) risk. One of the most persistent unresolved questions regarding menopausal ho
Externí odkaz:
https://doaj.org/article/23747e72e03144299f6791559e911b97
Autor:
Xiangguo Che, Xian Jin, Na Rae Park, Hee-June Kim, Hee-Soo Kyung, Hyun-Ju Kim, Jane B. Lian, Janet L. Stein, Gary S. Stein, Je-Yong Choi
Publikováno v:
Cells, Vol 12, Iss 7, p 1064 (2023)
TGF-β signaling is a vital regulator for maintaining articular cartilage homeostasis. Runx transcription factors, downstream targets of TGF-β signaling, have been studied in the context of osteoarthritis (OA). Although Runx partner core binding fac
Externí odkaz:
https://doaj.org/article/1b6314ddf1de49f9919e18a88f0a2261
Autor:
Andrew J. Fritz, Prachi N. Ghule, Rabail Toor, Louis Dillac, Jonah Perelman, Joseph Boyd, Jane B. Lian, Johnathan A. R. Gordon, Seth Frietze, Andre Van Wijnen, Janet L. Stein, Gary S. Stein
Publikováno v:
Critical Reviews in Eukaryotic Gene Expression. 33:85-97
Higher-order genomic organization supports the activation of histone genes in response to cell cycle regulatory cues that epigenetically mediates stringent control of transcription at the G1/S-phase transition. Histone locus bodies (HLBs) are dynamic
Autor:
J. Chayen
Publikováno v:
Cell Biochemistry and Function. 10:289-290
Autor:
D Vanvelzen
Publikováno v:
Cell Biology International Reports. 16:585-586