Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Jane, Owens"'
Autor:
Caroline Le Guiner, Xiao Xiao, Thibaut Larcher, Aude Lafoux, Corinne Huchet, Gilles Toumaniantz, Oumeya Adjali, Ignacio Anegon, Séverine Remy, Josh Grieger, Juan Li, Vahid Farrokhi, Hendrik Neubert, Jane Owens, Maritza McIntyre, Philippe Moullier, R. Jude Samulski
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 30, Iss , Pp 30-47 (2023)
Duchenne muscular dystrophy (DMD) is an X-linked disease caused by loss-of-function mutations in the dystrophin gene and is characterized by muscle wasting and early mortality. Adeno-associated virus-mediated gene therapy is being investigated as a t
Externí odkaz:
https://doaj.org/article/7a89e1515ecf4452944c4318d3851f25
Autor:
Christopher M. Brennan, Abby S. Hill, Michael St. Andre, Xianfeng Li, Vijaya Madeti, Susanne Breitkopf, Seth Garren, Liang Xue, Tamara Gilbert, Angela Hadjipanayis, Mara Monetti, Charles P. Emerson, Robert Moccia, Jane Owens, Nicolas Christoforou
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 11 (2022)
Externí odkaz:
https://doaj.org/article/1bbf0c3ccd564919803d206fc16f77d4
Publikováno v:
JCI Insight, Vol 6, Iss 12 (2021)
p38 MAPKs play a central role in orchestrating the cellular response to stress and inflammation and in the regulation of myogenesis. Potent inhibitors of p38 MAPKs have been pursued as potential therapies for several disease indications due to their
Externí odkaz:
https://doaj.org/article/a3214fa4553b41159e0f55af7a3cb596
Autor:
Shelli Schomaker, David Potter, Roscoe Warner, Jane Larkindale, Nicholas King, Amy C Porter, Jane Owens, Lindsay Tomlinson, John-Michael Sauer, Kent Johnson, Jiri Aubrecht
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0229753 (2020)
Serum activities of alanine and aspartate aminotransferases (ALT and AST) are used as gold standard biomarkers for the diagnosis of hepatocellular injury. Since ALT and AST lack liver specificity, the diagnosis of the onset of hepatocellular injury i
Externí odkaz:
https://doaj.org/article/3e5971e5348e466b88fb8c06f2416f09
Autor:
Michael St. Andre, Mark Johnson, Prashant N. Bansal, Jeremy Wellen, Andrew Robertson, Alan Opsahl, Peter M. Burch, Peter Bialek, Carl Morris, Jane Owens
Publikováno v:
Skeletal Muscle, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Background The treatments currently approved for Duchenne muscular dystrophy (DMD), a progressive skeletal muscle wasting disease, address the needs of only a small proportion of patients resulting in an urgent need for therapies that benefi
Externí odkaz:
https://doaj.org/article/21b83eb2ff50499ba194479c1f393cef
Autor:
Santosh Hariharan, Oana Lorintiu, Chia-Chin Lee, Eve Duchemin-Pelletier, Xianfeng Li, Aileen Healy, Regis Doyonnas, Luc Selig, Pauline Poydenot, Erwann Ventre, Andrea Weston, Jane Owens, Nicolas Christoforou
Duchenne muscular dystrophy (DMD) is a progressive and fatal muscle degenerating disease caused by dystrophin deficiency. Effective methods for drug discovery for the treatment of DMD requires systems to be physiologically relevant, scalable, and eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcb8fb30b4a5f99ff74734290a8ac0aa
https://doi.org/10.1101/2023.05.24.542079
https://doi.org/10.1101/2023.05.24.542079
Autor:
Hua Zhou, Henrik Olsen, Edward So, Emmanuel Mérigeon, Denis Rybin, Jane Owens, Gregory LaRosa, David S. Block, Scott E. Strome, Xiaoyu Zhang
Publikováno v:
Blood Advances, Vol 1, Iss 8, Pp 504-515 (2017)
Abstract: GL-2045 is a recombinant human immunoglobulin G1 (IgG1)–based Fc multimer designed to recapitulate the anti-inflammatory activities of intravenous immunoglobulin (IVIG) on the innate and adaptive immune responses. We used functional in vi
Externí odkaz:
https://doaj.org/article/93856454e7934fbba11284107095403d
Autor:
Wei Zhou, David Tester, Nicolas Christoforou, Changsung J. Kim, Mariana Bego, Lisa Keyes, Jane Owens, Jason Pinkstaff, Gabriel Brooks, Michael J. Ackerman
Publikováno v:
Heart Rhythm. 20:S41-S42
Autor:
Martina Gluscevic, Changsung J. Kim, David Tester, Nicolas Christoforou, Mariana Bego, Lisa Keyes, Jane Owens, Jason Pinkstaff, Ramin Garmany, Gabriel Brooks, Michael J. Ackerman
Publikováno v:
Heart Rhythm. 20:S42-S43