Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jane, McLaren"'
Autor:
Hadi Hajiali, Jane McLaren, Cristina Gonzalez-García, Salah Abdelrazig, Dong-Hyun Kim, Matthew J. Dalby, Manuel Salmerón-Sánchez, Felicity R.A.J. Rose
Publikováno v:
Engineered Regeneration, Vol 5, Iss 2, Pp 255-268 (2024)
Non-healing fractures, a global health concern arising from trauma, osteoporosis, and tumours, can lead to severe disabilities. Adenosine, integral to cellular energy metabolism, gains prominence in bone regeneration via adenosine A2B receptor activa
Externí odkaz:
https://doaj.org/article/6adc2cebbe1349f39c6015cbe6e5f738
Autor:
Raelene M. Cowie, Laura Macri-Pellizzeri, Jane McLaren, William J. Sanderson, Reda M. Felfel, Colin A. Scotchford, Brigitte E. Scammell, David M. Grant, Virginie Sottile, Louise M. Jennings
Publikováno v:
Royal Society Open Science, Vol 11, Iss 1 (2024)
Osteochondral grafts are used for repair of focal osteochondral lesions. Autologous grafts are the gold standard treatment; however, limited graft availability and donor site morbidity restrict use. Therefore, there is a clinical need for different g
Externí odkaz:
https://doaj.org/article/61a17e15969c435facfffdf6411f3e42
Autor:
Katherine A. Pitrolino, Reda M. Felfel, Laura Macri Pellizzeri, Jane McLaren, Alexander A. Popov, Virginie Sottile, Colin A. Scotchford, Brigitte E. Scammell, George A.F. Roberts, David M. Grant
Publikováno v:
Carbohydrate polymers. 282
An innovative approach was developed to engineer a multi-layered chitosan scaffold for osteochondral defect repair. A combination of freeze drying and porogen-leaching out methods produced a porous, bioresorbable scaffold with a distinct gradient of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a18241571d664aebee57336bc8744cb
https://pubmed.ncbi.nlm.nih.gov/35123750
https://pubmed.ncbi.nlm.nih.gov/35123750
Autor:
Richard O.C. Oreffo, Iria Echevarria, Nicola C. Foster, Hareklea Markides, Lisa J. White, Alicia J. El Haj, Jane McLaren, Cameron Black, Timothy Hopkins, Brigitte E. Scammell
Publikováno v:
Cells
Cells, Vol 10, Iss 1776, p 1776 (2021)
Volume 10
Issue 7
Cells, Vol 10, Iss 1776, p 1776 (2021)
Volume 10
Issue 7
The ovine critical-sized defect model provides a robust preclinical model for testing tissue-engineered constructs for use in the treatment of non-union bone fractures and severe trauma. A critical question in cell-based therapies is understanding th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd2e06662fcca3ae20c81f66abe594e
Publikováno v:
Journal of Biophotonics. 13
A wide range of biomaterials and tissue-engineered scaffolds are being investigated to support and stimulate bone healing in animal models. Using phantoms and rat cadavers, we investigated the feasibility of using spatially offset Raman spectroscopy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7b457d331e91ce9ee42397ee71f28d0
https://doi.org/10.1002/jbio.202000190
https://doi.org/10.1002/jbio.202000190
Autor:
Mahetab H. Amer, Sumana Shrestha, Francesco Pappalardo, Cristina González-García, Felicity R. A. J. Rose, Salah Abdelrazig, Jane McLaren, David Needham, Cameron Alexander, Sara Trujillo, Kevin M. Shakesheff, Morgan R. Alexander, Manuel Salmerón-Sánchez, Jing Qian Wong, Lee A. Stevens, Marta Alvarez-Paino, Jong Bong Lee, Dong-Hyun Kim
Publikováno v:
Biomaterials. 266
Mesenchymal stem cells have been the focus of intense research in bone development and regeneration. We demonstrate the potential of microparticles as modulating moieties of osteogenic response by utilizing their architectural features. Topographical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94bdb9597e40827f3750c7eb62e4b257
https://pubmed.ncbi.nlm.nih.gov/33096376
https://pubmed.ncbi.nlm.nih.gov/33096376
Autor:
Brigitte E. Scammell, Uresha Patel, Laura Macri-Pellizzeri, David M. Grant, Kazi M. Zakir Hossain, Jane McLaren, Ifty Ahmed, Virginie Sottile
Phosphate-based glasses (PBGs) are bioactive and fully degradable materials with tailorable degradation rates. PBGs can be produced as porous microspheres through a single-step process, using changes in their formulation and geometry to produce varyi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199f3bbcaf6751057750368405b9af65
https://nottingham-repository.worktribe.com/file/1782709/1/acsami.9b04603
https://nottingham-repository.worktribe.com/file/1782709/1/acsami.9b04603
Autor:
Màrian Matas Riera, Philippa Jane McLaren, Steven De Decker, Laureen M. Peters, Richard Lam, Thomas J. A. Cardy
Publikováno v:
Journal of Veterinary Emergency and Critical Care. 27:238-242
Objective To describe a case of successful medical management of subdural intracranial empyema and multifocal pneumonia in a domestic longhaired cat. Case Summary A 7-year-and-8-month-old male neutered domestic longhair cat presented with tachypnea,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f18578676a2d57c145ba077c6d250d82
https://doi.org/10.1111/vec.12566
https://doi.org/10.1111/vec.12566
Autor:
Max, Dooley, Aruna, Prasopthum, Zhiyu, Liao, Faris, Sinjab, Jane, McLaren, Felicity R A J, Rose, Jing, Yang, Ioan, Notingher
Publikováno v:
Biomedical Optics Express
Using phantom samples, we investigated the feasibility of spatially-offset Raman spectroscopy (SORS) as a tool for monitoring non-invasively the mineralization of bone tissue engineering scaffold in-vivo. The phantom samples consisted of 3D-printed s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0fe68b8bc623bd6b53f20056366619f0
https://pubmed.ncbi.nlm.nih.gov/31061762
https://pubmed.ncbi.nlm.nih.gov/31061762
Autor:
Brigitte E. Scammell, Andrew C.W. Zannettino, Neil D. Telling, Lisa J. White, Jane McLaren, Noura Alom, Hareklea Markides, E'atelaf A Al-Mutheffer, Richard O.C. Oreffo, Alicia J. El Haj
Publikováno v:
npj Regenerative Medicine, Vol 3, Iss 1, Pp 1-12 (2018)
NPJ Regenerative Medicine
NPJ Regenerative Medicine
The role of biomechanical stimuli, or mechanotransduction, in normal bone homeostasis and repair is understood to facilitate effective osteogenesis of mesenchymal stem cells (MSCs) in vitro. Mechanotransduction has been integrated into a multitude of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::331b8f0420f017389a28b76ce6b285be
https://doi.org/10.1038/s41536-018-0048-1
https://doi.org/10.1038/s41536-018-0048-1