Early moderate prenatal alcohol exposure and maternal diet impact offspring DNA methylation across species

Autor: Mitchell Bestry, Alexander N Larcombe, Nina Kresoje, Emily K Chivers, Chloe Bakker, James P Fitzpatrick, Elizabeth J Elliott, Jeffrey M Craig, Evelyne Muggli, Jane Halliday, Delyse Hutchinson, Sam Buckberry, Ryan Lister, Martyn Symons, David Martino

Publikováno v: eLife, Vol 12 (2024)

Alcohol consumption in pregnancy can affect genome regulation in the developing offspring but results have been contradictory. We employed a physiologically relevant murine model of short-term moderate prenatal alcohol exposure (PAE) resembling commo

Externí odkaz: https://doaj.org/article/3cc646f5fecb4ca6a990a0f7852fc124

Psychological consequences of a diagnosis of infertility in men: a systematic analysis

Autor: Sarah N Biggs, Jane Halliday, Karin Hammarberg

Publikováno v: Asian Journal of Andrology, Vol 26, Iss 1, Pp 10-19 (2024)

Almost half of infertility cases involve male infertility. Understanding the consequence of a diagnosis of male infertility, as a sole or partial contributor to the couples' infertility, to the mental health of men is required to ensure clinical care

Externí odkaz: https://doaj.org/article/c81b580ffb314f6daf95ff43de2f7700

Lifestyle and environmental risk factors for unexplained male infertility: study protocol for Australian Male Infertility Exposure (AMIE), a case–control study

Autor: Sarah N. Biggs, Joanne Kennedy, Sharon L. Lewis, Stephen Hearps, Moira K. O’Bryan, Robert McLachlan, Simon von Saldern, Georgina Chambers, Jane Halliday

Publikováno v: Reproductive Health, Vol 20, Iss 1, Pp 1-9 (2023)

Plain language summary Approximately 1 in 20 men are sub-fertile or infertile yet very little is known about the causes of male infertility. Research has suggested that lifestyle choices and environmental factors contribute to infertility, but more n

Externí odkaz: https://doaj.org/article/6aecb4c5d18a4a4783f429e67caf8771

Estimate of the Prevalence of Vascular Malformations

Autor: Anthony Penington, Roderic J Phillips, Nerida Sleebs, Jane Halliday

Publikováno v: Journal of Vascular Anomalies, Vol 4, Iss 3, p e068 (2023)

Objectives:. To estimate the prevalence of vascular malformations using retrospective data collected from 1999 to 2020 in a specialty vascular anomalies service. Methods:. The vascular anomalies service associated with the Royal Children’s Hospital

Externí odkaz: https://doaj.org/article/204fab6d6b074faf89df835e6df4851a

Machine learning driven prediction of cerebrospinal fluid rhinorrhoea following endonasal skull base surgery: A multicentre prospective observational study

Autor: CRANIAL Consortium, Adrito Das, Danyal Z. Khan, Danail Stoyanov, Hani J. Marcus, Soham Bandyopadhyay, Benjamin E. Schroeder, Vikesh Patel, Alice O’Donnell, Neurology and Neurosurgery Interest Group, British Neurosurgical Trainee Research Collaborative, Anastasios Giamouriadis, Pragnesh Bhatt, Bhaskar Ram, Adithya Varma, Philip Weir, Brendan Hanna, Theodore C. Hirst, Patrick McAleavey, Alessandro Paluzzi, Georgios Tsermoulas, Shahzada Ahmed, Wai Cheong Soon, Yasir Arafat Chowdhury, Suhaib Abualsaud, Shumail Mahmood, Paresh Naik, Zohra Haiderkhan, Rafid Al-Mahfoudh, Andrea Perera, Mircea Rus, Adam Williams, Charles Hand, Kumar Abhinav, Cristina Cernei, Aiman Dilnawaz, Richard Mannion, Thomas Santarius, James Tysome, Rishi Sharma, Angelos G. Kolias, Neil Donnelly, Ashwin Venkatesh, Caroline Hayhurst, Amr Mohamed, Benjamin Stew, Joseph Merola, Setthasorn Zhi Yang, Mahmoud Kamel, Mohammad Habibullah Khan, Sahibzada Abrar, Christopher Mckeon, Daniel McSweeney, Mohsen Javadpour, Peter Lacy, Daniel Murray, Elena Roman, Kismet Hossain-Ibrahim, David Bennett, Nathan McSorley, Adam Hounat, Patrick Statham, Mark Hughes, Alhafidz Hamdan, Caroline Scott, Jigi Moudgil-Joshi, Anuj Bahl, Anna Bjornson, Daniel Gatt, Nick Phillips, Neeraj Kalra, Melissa Bautista, Seerat Shirazi, Catherine E. Gilkes, Christopher P. Millward, Ahmad MS. Ali, Dimitris Paraskevopoulos, Jarnail Bal, Samir Matloob, Rhannon Lobo, Nigel Mendoza, Ramesh Nair, Arthur Dalton, Adarsh Nadig, Lucas Hernandez, Nick Thomas, Eleni Maratos, Jonathan Shapey, Sinan Al-Barazi, Asfand Baig Mirza, Mohamed Okasha, Prabhjot Singh Malhotra, Razna Ahmed, Neil L. Dorward, Joan Grieve, Parag Sayal, David Choi, Ivan Cabrilo, Hugo Layard Horsfall, Jonathan Pollock, Alireza Shoakazemi, Oscar Maccormac, Guru N K. Amirthalingam, Andrew Martin, Simon Stapleton, Florence Hogg, Daniel Richardson, Kanna Gnanalingham, Omar Pathmanaban, Daniel M. Fountain, Raj Bhalla, Cathal J. Hannan, Annabel Chadwick, Alistair Jenkins, Claire Nicholson, Syed Shumon, Mohamed Youssef, Callum Allison, Graham Dow, Iain Robertson, Laurence Johann Glancz, Murugan Sitaraman, Ashwin Kumaria, Ananyo Bagchi, Simon Cudlip, Jane Halliday, Rory J. Piper, Alexandros Boukas, Meriem Amarouche, Damjan Veljanoski, Samiul Muquit, Ellie Edlmann, Haritha Maripi, Yi Wang, Mehnaz Hossain, Andrew Alalade, Syed Maroof, Pradnya Patkar, Saurabh Sinha, Showkat Mirz, Duncan Henderson, Mohammad Saud Khan, Nijaguna Mathad, Jonathan Hempenstall, Difei Wang, Pavan Marwaha, Simon Shaw, Georgios Solomou, Alina Shrestha

Publikováno v: Frontiers in Oncology, Vol 13 (2023)

BackgroundCerebrospinal fluid rhinorrhoea (CSFR) is a common complication following endonasal skull base surgery, a technique that is fundamental to the treatment of pituitary adenomas and many other skull base tumours. The CRANIAL study explored CSF

Externí odkaz: https://doaj.org/article/57c49257e0e04c159faceaf78654f6a9