Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Jane, Antony"'
Autor:
Linda J. vanWeele, Sabra I. Djomehri, Shang Cai, Jane Antony, Shaheen S. Sikandar, Dalong Qian, William H. D. Ho, Robert B. West, Ferenc A. Scheeren, Michael F. Clarke
Publikováno v:
Molecular Oncology, Vol 16, Iss 17, Pp 3128-3145 (2022)
As precision medicine increases the response rate of treatment, tumors frequently bypass inhibition, and reoccur. In order for treatment to be effective long term, the mechanisms enabling treatment adaptation need to be understood. Here, we report a
Externí odkaz:
https://doaj.org/article/8d6bdff9fa234733908de5b2990ded0f
Autor:
Felicia Reinitz, Elizabeth Y Chen, Benedetta Nicolis di Robilant, Bayarsaikhan Chuluun, Jane Antony, Robert C Jones, Neha Gubbi, Karen Lee, William Hai Dang Ho, Sai Saroja Kolluru, Dalong Qian, Maddalena Adorno, Katja Piltti, Aileen Anderson, Michelle Monje, H Craig Heller, Stephen R Quake, Michael F Clarke
Publikováno v:
eLife, Vol 11 (2022)
Alzheimer’s disease (AD) is a progressive neurodegenerative disease observed with aging that represents the most common form of dementia. To date, therapies targeting end-stage disease plaques, tangles, or inflammation have limited efficacy. Theref
Externí odkaz:
https://doaj.org/article/92c5abc287934048bbc8abb6eae7052f
Autor:
James R. Birtley, Mohammad Alomary, Elisa Zanini, Jane Antony, Zachary Maben, Grant C. Weaver, Claudia Von Arx, Manuela Mura, Aline T. Marinho, Haonan Lu, Eloise V. N. Morecroft, Evdoxia Karali, Naomi E. Chayen, Edward W. Tate, Mollie Jurewicz, Lawrence J. Stern, Chiara Recchi, Hani Gabra
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
OPCML is a tumour suppressor gene that is epigenetically silenced in ovarian cancer and is somatically mutated in various cancers. Here, the authors solve the X-ray crystal structure of OPCML and model clinically relevant mutations that could contrib
Externí odkaz:
https://doaj.org/article/0d39746c3dc44914b53cf2c2f0ee8062
Autor:
Hani Gabra, Chiara Recchi, Justin Stebbing, Mona El-Bahrawy, Sebastian Vaughan, Arthur B. McKie, Imoh S. Okon, Evdoxia Karali, Jane Antony, Louay S. Louis, Elisa Zanini
Opioid-binding protein/cell adhesion molecule-like (OPCML) is a tumor-suppressor gene that is frequently inactivated in ovarian cancer and many other cancers by somatic methylation. We have previously shown that OPCML exerts its suppressor function b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a80f95190db02e253f295bd69d63e1ce
https://doi.org/10.1158/1535-7163.c.6538779.v1
https://doi.org/10.1158/1535-7163.c.6538779.v1
Autor:
Hani Gabra, Chiara Recchi, Justin Stebbing, Mona El-Bahrawy, Sebastian Vaughan, Arthur B. McKie, Imoh S. Okon, Evdoxia Karali, Jane Antony, Louay S. Louis, Elisa Zanini
Supplementary figures legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2285bdb99dbc833d66ee3e62c6eb5d52
https://doi.org/10.1158/1535-7163.22507752
https://doi.org/10.1158/1535-7163.22507752
Autor:
Hani Gabra, Chiara Recchi, Justin Stebbing, Mona El-Bahrawy, Sebastian Vaughan, Arthur B. McKie, Imoh S. Okon, Evdoxia Karali, Jane Antony, Louay S. Louis, Elisa Zanini
Schematic view of the constructs used in the mammalian 2-hybrid assays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a73efad0c312e3408e71023cccf696ef
https://doi.org/10.1158/1535-7163.22507770
https://doi.org/10.1158/1535-7163.22507770
Autor:
Shaheen S. Sikandar, Gunsagar S. Gulati, Jane Antony, Isobel Fetter, Angera H. Kuo, William Hai Dang Ho, Veronica Haro-Acosta, Soumyashree Das, Chloé B. Steen, Thiago Almeida Pereira, Dalong Qian, Philip A. Beachy, Fredrick Dirbas, Kristy Red-Horse, Terence H. Rabbitts, Jean Paul Thiery, Aaron M. Newman, Michael F. Clarke
Publikováno v:
Science Advances. 8
Metastasis is responsible for most breast cancer–related deaths; however, identifying the cellular determinants of metastasis has remained challenging. Here, we identified a minority population of immatureTHY1+/VEGFA+tumor epithelial cells in human
Publikováno v:
Molecular & Cellular Oncology, Vol 4, Iss 2 (2017)
In a recent publication in Science Signaling, we showed that a Mes molecular subtype of epithelial ovarian cancer (EOC) harboring epithelial-mesenchymal transition (EMT) features has a unique signaling network downstream of the GAS6/AXL pathway. Our
Externí odkaz:
https://doaj.org/article/400fb4964cfe40cbb258deb845564234
Autor:
Robert C, Jones, Jim, Karkanias, Mark A, Krasnow, Angela Oliveira, Pisco, Stephen R, Quake, Julia, Salzman, Nir, Yosef, Bryan, Bulthaup, Phillip, Brown, William, Harper, Marisa, Hemenez, Ravikumar, Ponnusamy, Ahmad, Salehi, Bhavani A, Sanagavarapu, Eileen, Spallino, Ksenia A, Aaron, Waldo, Concepcion, James M, Gardner, Burnett, Kelly, Nikole, Neidlinger, Zifa, Wang, Sheela, Crasta, Saroja, Kolluru, Maurizio, Morri, Serena Y, Tan, Kyle J, Travaglini, Chenling, Xu, Marcela, Alcántara-Hernández, Nicole, Almanzar, Jane, Antony, Benjamin, Beyersdorf, Deviana, Burhan, Kruti, Calcuttawala, Matthew M, Carter, Charles K F, Chan, Charles A, Chang, Stephen, Chang, Alex, Colville, Rebecca N, Culver, Ivana, Cvijović, Gaetano, D'Amato, Camille, Ezran, Francisco X, Galdos, Astrid, Gillich, William R, Goodyer, Yan, Hang, Alyssa, Hayashi, Sahar, Houshdaran, Xianxi, Huang, Juan C, Irwin, SoRi, Jang, Julia Vallve, Juanico, Aaron M, Kershner, Soochi, Kim, Bernhard, Kiss, William, Kong, Maya E, Kumar, Angera H, Kuo, Rebecca, Leylek, Baoxiang, Li, Gabriel B, Loeb, Wan-Jin, Lu, Sruthi, Mantri, Maxim, Markovic, Patrick L, McAlpine, Antoine, de Morree, Karim, Mrouj, Shravani, Mukherjee, Tyler, Muser, Patrick, Neuhöfer, Thi D, Nguyen, Kimberly, Perez, Ragini, Phansalkar, Nazan, Puluca, Zhen, Qi, Poorvi, Rao, Hayley, Raquer-McKay, Nicholas, Schaum, Bronwyn, Scott, Bobak, Seddighzadeh, Joe, Segal, Sushmita, Sen, Shaheen, Sikandar, Sean P, Spencer, Lea C, Steffes, Varun R, Subramaniam, Aditi, Swarup, Michael, Swift, Will, Van Treuren, Emily, Trimm, Stefan, Veizades, Sivakamasundari, Vijayakumar, Kim Chi, Vo, Sevahn K, Vorperian, Wanxin, Wang, Hannah N W, Weinstein, Juliane, Winkler, Timothy T H, Wu, Jamie, Xie, Andrea R, Yung, Yue, Zhang, Angela M, Detweiler, Honey, Mekonen, Norma F, Neff, Rene V, Sit, Michelle, Tan, Jia, Yan, Gregory R, Bean, Vivek, Charu, Erna, Forgó, Brock A, Martin, Michael G, Ozawa, Oscar, Silva, Angus, Toland, Venkata N P, Vemuri, Shaked, Afik, Kyle, Awayan, Olga Borisovna, Botvinnik, Ashley, Byrne, Michelle, Chen, Roozbeh, Dehghannasiri, Adam, Gayoso, Alejandro A, Granados, Qiqing, Li, Gita, Mahmoudabadi, Aaron, McGeever, Julia Eve, Olivieri, Madeline, Park, Neha, Ravikumar, Geoff, Stanley, Weilun, Tan, Alexander J, Tarashansky, Rohan, Vanheusden, Peter, Wang, Sheng, Wang, Galen, Xing, Rebecca, Culver, Les, Dethlefsen, Po-Yi, Ho, Shixuan, Liu, Jonathan S, Maltzman, Ross J, Metzger, Koki, Sasagawa, Rahul, Sinha, Hanbing, Song, Bruce, Wang, Steven E, Artandi, Philip A, Beachy, Michael F, Clarke, Linda C, Giudice, Franklin W, Huang, Kerwyn Casey, Huang, Juliana, Idoyaga, Seung K, Kim, Mark, Krasnow, Christin S, Kuo, Patricia, Nguyen, Thomas A, Rando, Kristy, Red-Horse, Jeremy, Reiter, David A, Relman, Justin L, Sonnenburg, Albert, Wu, Sean M, Wu, Tony, Wyss-Coray
Publikováno v:
Science
Tabula Sapiens Consortium* 2022, ' The Tabula Sapiens : A multiple-organ, single-cell transcriptomic atlas of humans ', Science (New York, N.Y.), vol. 376, no. 6594, pp. eabl4896 . https://doi.org/10.1126/science.abl4896
Tabula Sapiens Consortium* 2022, ' The Tabula Sapiens : A multiple-organ, single-cell transcriptomic atlas of humans ', Science (New York, N.Y.), vol. 376, no. 6594, pp. eabl4896 . https://doi.org/10.1126/science.abl4896
INTRODUCTION: Although the genome is often called the blueprint of an organism, it is perhaps more accurate to describe it as a parts list composed of the various genes that may or may not be used in the different cell types of a multicellular organi
Autor:
Benedetta Nicolis di Robilant, Elizabeth Y Chen, Felicia Reinitz, Bayarsaikhan Chuluun, Jane Antony, Robert C Jones, Neha Gubbi, Karen Lee, William Hai Dang Ho, Sai Saroja Kolluru, Dalong Qian, Maddalena Adorno, Katja Piltti, Aileen Anderson, Michelle Monje, H Craig Heller, Stephen R Quake, Michael F Clarke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c06b69fb3ac0c75f6f4029ed4b8b982
https://doi.org/10.7554/elife.66037.sa2
https://doi.org/10.7554/elife.66037.sa2