Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jandre de Villiers"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
The use of bioprostheses for heart valve therapy has gradually evolved over several decades and both surgical and transcatheter devices are now highly successful. The rapid expansion of the transcatheter concept has clearly placed a significant onus
Externí odkaz:
https://doaj.org/article/a3a02b09c0ac4ba8b88ddf4c67e8fb4b
Autor:
Helen Ilsley, Peter Zilla, Paul Human, Jandre de Villiers, David F. Williams, Deon Bezuidenhout, Chima Ofoegbu
Publikováno v:
European Journal of Cardio-Thoracic Surgery. 58:1192-1200
OBJECTIVES While decellularization has previously significantly improved the durability of bioprosthetic tissue, remnant immunogenicity may yet necessitate masking through crosslinking. To alleviate the fears of reintroducing the risk of calcific deg
Autor:
Jielin Zhang, Andy-Mark W. H. Thunnissen, Jandre de Villiers, Gerrit J. Poelarends, Vinod Puthan Veetil, Hans Raj, Harshwardhan Poddar
Publikováno v:
Biochemistry
Biochemistry, 57(26), 3752-3763. AMER CHEMICAL SOC
Biochemistry, 57(26), 3752-3763. AMER CHEMICAL SOC
The natural aminocarboxylic acid product ethylenediamine- N, N'-disuccinic acid [( S, S)-EDDS] is able to form a stable complex with metal ions, making it an attractive biodegradable alternative for the synthetic metal chelator ethylenediaminetetraac
Autor:
Vinod Puthan Veetil, Jandre de Villiers, Hans Raj, Keiko Shimamoto, Ben L. Feringa, Wim J. Quax, Dick B. Janssen, Wiktor Szymanski, Gerrit J. Poelarends
Publikováno v:
Chemistry, 19(34), 11148-11152. Wiley-VCH Verlag GmbH & Co. KGaA
Enzymatic amino acid synthesis: Kinetic resolution and asymmetric synthesis of various valuable 3-substituted aspartic acids, which were obtained in fair to good yields with diastereomeric ratio values of up to98:2 and enantiomeric excess values of u
Autor:
Marianne de Villiers, Hans Raj, Vinod Puthan Veetil, Gerrit J. Poelarends, Jandre de Villiers
Publikováno v:
ACS chemical biology. 7(10):1618-1628
Ammonia lyases catalyze the formation of alpha-beta-unsaturated bonds by the elimination of ammonia from their substrates. This conceptually straightforward reaction has been the emphasis of many studies, with the main focus on the catalytic mechanis
Autor:
Dick B. Janssen, Jandre de Villiers, Henriëtte J. Rozeboom, Carlos R. Reis, Hans Raj, Frank J. Dekker, Gerrit J. Poelarends, Stefaan Marie André De Wildeman, Wiktor Szymanski, Andy-Mark W. H. Thunnissen, Marianne de Villiers, Ben L. Feringa, Wim J. Quax, Vinod Puthan Veetil
Publikováno v:
Nature Chemistry, 4(6), 478-484. Nature Publishing Group
The redesign of enzymes to produce catalysts for a predefined transformation remains a major challenge in protein engineering. Here, we describe the structure-based engineering of methylaspartate ammonia lyase (which in nature catalyses the conversio
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 16(33)
Fluorine-containing amino acids have been used with great success as mechanism-based inhibitors of pyridoxal phosphate (PLP)-dependent enzymes, and the influence of fluorine on the conformation of molecules has also been extensively studied and pract
Autor:
Jandre de Villiers, Marianne de Villiers, Gerrit J. Poelarends, Hans Raj, Edzard M. Geertsema
Publikováno v:
ChemCatChem. 7:1883-1883
Autor:
Harish Appa, Kenneth Park, Deon Bezuidenhout, Braden van Breda, Bruce de Jongh, Jandré de Villiers, Reno Chacko, Jacques Scherman, Chima Ofoegbu, Justiaan Swanevelder, Michael Cousins, Paul Human, Robin Smith, Ferdinand Vogt, Bruno K. Podesser, Christoph Schmitz, Lenard Conradi, Hendrik Treede, Holger Schröfel, Theodor Fischlein, Martin Grabenwöger, Xinjin Luo, Heather Coombes, Simon Matskeplishvili, David F. Williams, Peter Zilla
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Leaflet durability and costs restrict contemporary trans-catheter aortic valve replacement (TAVR) largely to elderly patients in affluent countries. TAVR that are easily deployable, avoid secondary procedures and are also suitable for younger patient
Externí odkaz:
https://doaj.org/article/e330bb4697254abdad4cf49e1a07fb18