Successful anti-tumor effects with two novel bifunctional chemotherapeutic compounds that combine a LAT1 substrate with cytotoxic moieties in aggressive T-cell lymphomas.

Autor: Murga-Zamalloa C; Department of Pathology, University of Illinois at Chicago, 840 S Wood Street, 260 CMET, Chicago, IL 60607, United States., Webb S; Department of Pathology, University of Illinois at Chicago, 840 S Wood Street, 260 CMET, Chicago, IL 60607, United States., Reneau J; Department of Internal Medicine, Ohio State University, Columbus, OH 43210, United States., Zevallos A; Department of Pathology, University of Illinois at Chicago, 840 S Wood Street, 260 CMET, Chicago, IL 60607, United States., Danos-Diaz P; Department of Pathology, University of Illinois at Chicago, 840 S Wood Street, 260 CMET, Chicago, IL 60607, United States., Perez-Silos V; Department of Pathology, University of Illinois at Chicago, 840 S Wood Street, 260 CMET, Chicago, IL 60607, United States., Rodriguez M; Quadriga BioSciences, Inc., Los Altos CA 94022, United States., Gao G; Acme Bioscience, Inc., Palo Alto, CA 94303, United States., Fischer WN; Quadriga BioSciences, Inc., Los Altos CA 94022, United States., Jandeleit B; Quadriga BioSciences, Inc., Los Altos CA 94022, United States., Wilcox R; Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48105, United States.

Publikováno v: Leukemia research reports [Leuk Res Rep] 2023 Nov 22; Vol. 21, pp. 100398. Date of Electronic Publication: 2023 Nov 22 (Print Publication: 2024).

A Novel Brain-Permeant Chemotherapeutic Agent for the Treatment of Brain Metastasis in Triple-Negative Breast Cancer.

Autor: Deng J; Department of Neurosurgery, Stanford University, Stanford, California.; Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China., Chernikova SB; Department of Neurosurgery, Stanford University, Stanford, California., Wang Y; Department of Neurosurgery, Stanford University, Stanford, California.; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, China., Rodriguez ML; Quadriga BioSciences, Inc., Los Altos, California., Andersen SJ; Department of Neurosurgery, Stanford University, Stanford, California., Umeh-Garcia MC; Department of Neurosurgery, Stanford University, Stanford, California., Godfrey BO; Department of Neurosurgery, Stanford University, Stanford, California., Ahmadian SS; Department of Pathology, Stanford University, Stanford, California., Fischer WN; Quadriga BioSciences, Inc., Los Altos, California., Koller KJ; Quadriga BioSciences, Inc., Los Altos, California., Jandeleit B; Quadriga BioSciences, Inc., Los Altos, California., Ringold GM; Quadriga BioSciences, Inc., Los Altos, California., Gephart MH; Department of Neurosurgery, Stanford University, Stanford, California. mghayden@stanford.edu.

Publikováno v: Molecular cancer therapeutics [Mol Cancer Ther] 2021 Nov; Vol. 20 (11), pp. 2110-2116. Date of Electronic Publication: 2021 Oct 11.

Genetic Engineering in Combination with Semi-Synthesis Leads to a New Route for Gram-Scale Production of the Immunosuppressive Natural Product Brasilicardin A.

Autor: Botas A; Departamento de Biología Funcional e Instituto Universitario de Oncología del Principado de Asturias, Universidad de Oviedo and Instituto de Investigación Sanitaria de Asturias (ISPA), c/ Julián Clavería s/n., 33006, Oviedo, Spain., Eitel M; Department of Pharmaceutical Chemistry, Institute of Pharmaceutical Sciences, University of Tübingen, Auf der Morgenstelle 8, 72076, Tübingen, Germany., Schwarz PN; Department of Microbiology and Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Auf der Morgenstelle 28, 72076, Tübingen, Germany., Buchmann A; Department of Pharmaceutical Biology, Institute of Pharmaceutical Sciences, University of Tübingen, Auf der Morgenstelle 8, 72076, Tübingen, Germany., Costales P; EntreChem S.L., Vivero Ciencias de la Salud, c/ Colegio Santo Domingo de Guzmán, s/n, 33011, Oviedo, Spain., Núñez LE; EntreChem S.L., Vivero Ciencias de la Salud, c/ Colegio Santo Domingo de Guzmán, s/n, 33011, Oviedo, Spain., Cortés J; EntreChem S.L., Vivero Ciencias de la Salud, c/ Colegio Santo Domingo de Guzmán, s/n, 33011, Oviedo, Spain., Morís F; EntreChem S.L., Vivero Ciencias de la Salud, c/ Colegio Santo Domingo de Guzmán, s/n, 33011, Oviedo, Spain., Krawiec M; Department of Molecular Microbiology, Faculty of Biotechnology, University of Wrocław, ul. F. Joliot-Curie 14A, 50-383, Wrocław, Poland., Wolański M; Department of Molecular Microbiology, Faculty of Biotechnology, University of Wrocław, ul. F. Joliot-Curie 14A, 50-383, Wrocław, Poland., Gust B; Department of Pharmaceutical Biology, Institute of Pharmaceutical Sciences, University of Tübingen, Auf der Morgenstelle 8, 72076, Tübingen, Germany., Rodriguez M; Quadriga BioSciences, Inc., 339 S. San Antonio Road, Suite 2A, Los Altos, CA, 94022, USA., Fischer WN; Quadriga BioSciences, Inc., 339 S. San Antonio Road, Suite 2A, Los Altos, CA, 94022, USA., Jandeleit B; Quadriga BioSciences, Inc., 339 S. San Antonio Road, Suite 2A, Los Altos, CA, 94022, USA., Zakrzewska-Czerwińska J; Department of Molecular Microbiology, Faculty of Biotechnology, University of Wrocław, ul. F. Joliot-Curie 14A, 50-383, Wrocław, Poland., Wohlleben W; Department of Microbiology and Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Auf der Morgenstelle 28, 72076, Tübingen, Germany., Stegmann E; Department of Microbiology and Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Auf der Morgenstelle 28, 72076, Tübingen, Germany., Koch P; Department of Pharmaceutical Chemistry, Institute of Pharmaceutical Sciences, University of Tübingen, Auf der Morgenstelle 8, 72076, Tübingen, Germany., Méndez C; Departamento de Biología Funcional e Instituto Universitario de Oncología del Principado de Asturias, Universidad de Oviedo and Instituto de Investigación Sanitaria de Asturias (ISPA), c/ Julián Clavería s/n., 33006, Oviedo, Spain., Gross H; Department of Pharmaceutical Biology, Institute of Pharmaceutical Sciences, University of Tübingen, Auf der Morgenstelle 8, 72076, Tübingen, Germany.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2021 Jun 07; Vol. 60 (24), pp. 13536-13541. Date of Electronic Publication: 2021 May 01.

Asymmetric Synthesis of 3-Substituted 4-Oxoesters Using the SAMP-/RAMP-Hydrazone Method.

Autor: Enders, D., Baus, U., Müller, P., Nicolaou, K.C., Jandeleit, B.

Publikováno v: Molecules Online; Jun1998, Vol. 2 Issue 1, p15-21, 7p

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