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pro vyhledávání: '"Janarthanan Narayanasamy"'
Autor:
Raymond F. Schinazi, Manik R. Pullagurla, Chung K. Chu, Jianing Wang, Janarthanan Narayanasamy, Ashoke Sharon
Publikováno v:
Antiviral Research. 75:198-209
Prodrugs of (−)-β- d -(2 R ,4 R )-1,3-dioxolane-2,6-diamino purine (DAPD), organic salts of DAPD, 5′- l -valyl DAPD and N − 1 substituted (−)-β- d -(2 R ,4 R )-1,3-dioxolane guanosine (DXG) have been synthesized with the objective of findin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d518335a7662a7ee56df2eebf644cfa9
https://doi.org/10.1016/j.antiviral.2007.03.005
https://doi.org/10.1016/j.antiviral.2007.03.005
Autor:
Raymond F. Schinazi, Aleksandr Obikhod, Selwyn J. Hurwitz, Janarthanan Narayanasamy, Ghazia Asif, Harold M. McClure, David Delinsky, Chung K. Chu
Publikováno v:
Antimicrobial Agents and Chemotherapy. 51:2424-2429
β-d-Dioxolane-thymine (D-DOT) has potent and selective in vitro activity against several clinically important resistant human immunodeficiency virus (HIV) mutants and is in advanced preclinical development. Therefore, the single-dose intravenous and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a14cebc4472e01bb8a0fe724fe35fb46
https://doi.org/10.1128/aac.01498-06
https://doi.org/10.1128/aac.01498-06
Publikováno v:
Bioorganic & Medicinal Chemistry. 14:2178-2189
A series of phosphoramidate and phosphate prodrugs of DOT were synthesized via dichlorophosphate or H-phosphonate chemistry and evaluated for their anti-HIV activity against LAI M184V mutants in PBM cells as well as for their cytotoxicity. The antivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d3eaa258bb1c47c256b5ecb6b3d760
https://doi.org/10.1016/j.bmc.2005.11.008
https://doi.org/10.1016/j.bmc.2005.11.008
Publikováno v:
Antiviral chemistrychemotherapy. 17(6)
The synthesis, characterization, anti-HIV activity and cytotoxicity of dendrimers of (–)-β-D-(2 R,4 R)-dioxolane-thymine (DOT) and polyethylene glycol (PEG)–DOT conjugates are described. Dendrimers in this study were polyamidoamine (PAMAM) gener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::092a2ad2f19cc1e2998e291a0c9d8203
https://pubmed.ncbi.nlm.nih.gov/17249246
https://pubmed.ncbi.nlm.nih.gov/17249246
Akademický článek
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Autor:
Ramadas, Krishnamurthy, Suresh, Govindaraghavan, Janarthanan, Narayanasamy, Masilamani, Selladurai
Publikováno v:
Pesticide Science (now called Pest Management Science); February 1998, Vol. 52 Issue: 2 p145-151, 7p
Publikováno v:
In Tetrahedron Letters 1993 34(40):6447-6450