Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Janani Prahlad"'
Autor:
Jennifer L. Endres, Sujata S. Chaudhari, Xinyan Zhang, Janani Prahlad, Shu-Qi Wang, Lily A. Foley, Sorin Luca, Jeffrey L. Bose, Vinai C. Thomas, Kenneth W. Bayles
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT The Staphylococcus aureus cidABC and lrgAB operons encode members of a well-conserved family of proteins thought to be involved in programmed cell death (PCD). Based on the structural similarities that CidA and LrgA share with bacteriophage
Externí odkaz:
https://doaj.org/article/be28907b481d4d2c83ab22a975c466e8
Autor:
John Victor Napoleon, Satish Sagar, Sydney P. Kubica, Lidia Boghean, Smit Kour, Hannah M. King, Yogesh A. Sonawane, Ayrianne J. Crawford, Nagsen Gautam, Smitha Kizhake, Pawel A. Bialk, Eric Kmiec, Jayapal Reddy Mallareddy, Prathamesh P. Patil, Sandeep Rana, Sarbjit Singh, Janani Prahlad, Paul M. Grandgenett, Gloria E. O. Borgstahl, Gargi Ghosal, Yazen Alnouti, Michael A. Hollingsworth, Prakash Radhakrishnan, Amarnath Natarajan
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Activation of inhibitor of nuclear factor NF-κB kinase subunit-β (IKKβ), characterized by phosphorylation of activation loop serine residues 177 and 181, has been implicated in the early onset of cancer. On the other hand, tissue-specific IKKβ kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee2183724df8b2fa739b509626495a6
https://doi.org/10.1073/pnas.2115071119
https://doi.org/10.1073/pnas.2115071119
Autor:
Janani Prahlad, Yifeng Yuan, Valérie de Crécy-Lagard, Jiusheng Lin, Mark A. Wilson, Chou Wei Chang, Yilun Liu, Dirk Iwata-Reuyl
Publikováno v:
J Biol Chem
DUF328 family proteins are present in many prokaryotes, however their molecular activities are unknown. The Escherichia coli DUF328 protein YaaA is a member of the OxyR regulon and is protective against oxidative stress. Because uncharacterized prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0addf2883a2484a7d58adcf5b95a0db
https://doi.org/10.1074/jbc.ra120.015055
https://doi.org/10.1074/jbc.ra120.015055
Autor:
Surender Khurana, Gloria E. O. Borgstahl, William E. Lutz, Janani Prahlad, Kenneth W. Bayles, Mara J. Broadhurst, Andy Schnaubelt, Lucas R. Struble, Savanna A. Wallin
The COVID-19 pandemic caused by SARS-CoV-2 has applied significant pressure on overtaxed healthcare around the world, underscoring the urgent need for rapid diagnosis and treatment. We have developed a bacterial strategy for the expression and purifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fb345150c90d87733800f8e9a47279b
https://doi.org/10.1101/2021.02.03.429601
https://doi.org/10.1101/2021.02.03.429601
Publikováno v:
Journal of Neurochemistry. 130:839-853
The oxidation of a key cysteine residue (Cys106) in the parkinsonism-associated protein DJ-1 regulates its ability to protect against oxidative stress and mitochondrial damage. Cys106 interacts with a neighboring protonated Glu18 residue, stabilizing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e0147f3577c840dcd2bf8500c5f34d0
https://doi.org/10.1111/jnc.12763
https://doi.org/10.1111/jnc.12763
Autor:
Andriy, Kryshtafovych, John, Moult, Arnaud, Baslé, Alex, Burgin, Timothy K, Craig, Robert A, Edwards, Deborah, Fass, Marcus D, Hartmann, Mateusz, Korycinski, Richard J, Lewis, Donald, Lorimer, Andrei N, Lupas, Janet, Newman, Thomas S, Peat, Kurt H, Piepenbrink, Janani, Prahlad, Mark J, van Raaij, Forest, Rohwer, Anca M, Segall, Victor, Seguritan, Eric J, Sundberg, Abhimanyu K, Singh, Mark A, Wilson, Torsten, Schwede
Publikováno v:
Proteins
The Critical Assessment of protein Structure Prediction (CASP) experiment would not have been possible without the prediction targets provided by the experimental structural biology community. In this article, selected crystallographers providing tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::75d040900b2cd054535d59b3858ecd41
https://pubmed.ncbi.nlm.nih.gov/26473983
https://pubmed.ncbi.nlm.nih.gov/26473983
DJ-1 is a conserved, disease-associated protein that protects against oxidative stress and mitochondrial damage in multiple organisms. Human DJ-1 contains a functionally essential cysteine residue (Cys106) whose oxidation is important for regulating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::071733bb9b6ddd2d7b718cd98aa6fd11
https://europepmc.org/articles/PMC3348460/
https://europepmc.org/articles/PMC3348460/