Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Janane F. Rahbani"'
Autor:
Janane F. Rahbani, Lawrence Kazak
Publikováno v:
Cell metabolism. 34(9)
In this issue of Cell Metabolism, Xue et al. propose that the mitochondrial calcium uniporter (MCU) binds uncoupling protein 1 (UCP1) via the MCU regulator (EMRE) to form a protein complex that the authors term the "thermoporter." Through gain- and l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb90f6040ac3c861dd80d0ba472c203f
https://pubmed.ncbi.nlm.nih.gov/35977541
https://pubmed.ncbi.nlm.nih.gov/35977541
Autor:
Janane F, Rahbani, Charlotte, Scholtes, Damien M, Lagarde, Mohammed F, Hussain, Anna, Roesler, Christien B, Dykstra, Jakub, Bunk, Bozena, Samborska, Shannon L, O'Brien, Emma, Tripp, Alain, Pacis, Anthony R, Angueira, Olivia S, Johansen, Jessica, Cinkornpumin, Ishtiaque, Hossain, Matthew D, Lynes, Yang, Zhang, Andrew P, White, William A, Pastor, Maria, Chondronikola, Labros, Sidossis, Samuel, Klein, Anastasia, Kralli, Aaron M, Cypess, Steen B, Pedersen, Niels, Jessen, Yu-Hua, Tseng, Zachary, Gerhart-Hines, Patrick, Seale, Davide, Calebiro, Vincent, Giguère, Lawrence, Kazak
Publikováno v:
Nature metabolism. 4(11)
Noradrenaline (NA) regulates cold-stimulated adipocyte thermogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1f3b3487f1088e41970c519982e02956
https://pubmed.ncbi.nlm.nih.gov/36344764
https://pubmed.ncbi.nlm.nih.gov/36344764
Publikováno v:
Methods Mol Biol
Methods in Molecular Biology ISBN: 9781071620861
Methods in Molecular Biology ISBN: 9781071620861
Thermogenic adipose tissue plays a vital function in regulating whole-body energy expenditure and nutrient homeostasis due to its capacity to dissipate chemical energy as heat, in a process called non-shivering thermogenesis. A reduction of creatine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1737ef0c1a564ffa82ef8de28334faba
https://pubmed.ncbi.nlm.nih.gov/35167096
https://pubmed.ncbi.nlm.nih.gov/35167096
Autor:
Janane F. Rahbani, Charlotte Scholtes, Damien M. Lagarde, Mohammed F. Hussain, Anna Roesler, Christien B. Dykstra, Jakub Bunk, Bozena Samborska, Shannon L. O’Brien, Emma Tripp, Alain Pacis, Anthony R. Angueira, Olivia S. Johansen, Jessica Cinkornpumin, Ishtiaque Hossain, Matthew D. Lynes, Yang Zhang, Andrew P. White, William A. Pastor, Maria Chondronikola, Labros Sidossis, Samuel Klein, Anastasia Kralli, Aaron M. Cypess, Steen B. Pedersen, Niels Jessen, Yu-Hua Tseng, Zachary Gerhart-Hines, Patrick Seale, Davide Calebiro, Vincent Giguère, Lawrence Kazak
Publikováno v:
Rahbani, J F, Scholtes, C, Lagarde, D M, Hussain, M F, Roesler, A, Dykstra, C B, Bunk, J, Samborska, B, O’Brien, S L, Tripp, E, Pacis, A, Angueira, A R, Johansen, O S, Cinkornpumin, J, Hossain, I, Lynes, M D, Zhang, Y, White, A P, Pastor, W A, Chondronikola, M, Sidossis, L, Klein, S, Kralli, A, Cypess, A M, Pedersen, S B, Jessen, N, Tseng, Y H, Gerhart-Hines, Z, Seale, P, Calebiro, D, Giguère, V & Kazak, L 2022, ' ADRA1A–Gα q signalling potentiates adipocyte thermogenesis through CKB and TNAP ', Nature Metabolism, vol. 4, no. 11, pp. 1459-1473 . https://doi.org/10.1038/s42255-022-00667-w
Rahbani, J F, Scholtes, C, Lagarde, D M, Hussain, M F, Roesler, A, Dykstra, C B, Bunk, J, Samborska, B, O'Brien, S L, Tripp, E, Pacis, A, Angueira, A R, Johansen, O S, Cinkornpumin, J, Hossain, I, Lynes, M D, Zhang, Y, White, A P, Pastor, W A, Chondronikola, M, Sidossis, L, Klein, S, Kralli, A, Cypess, A M, Pedersen, S B, Jessen, N, Tseng, Y-H, Gerhart-Hines, Z, Seale, P, Calebiro, D, Giguère, V & Kazak, L 2022, ' ADRA1A-Gαq signalling potentiates adipocyte thermogenesis through CKB and TNAP ', Nature Metabolism, vol. 4, no. 11, pp. 1459-1473 . https://doi.org/10.1038/s42255-022-00667-w
Nature metabolism, vol 4, iss 11
Rahbani, J F, Scholtes, C, Lagarde, D M, Hussain, M F, Roesler, A, Dykstra, C B, Bunk, J, Samborska, B, O'Brien, S L, Tripp, E, Pacis, A, Angueira, A R, Johansen, O S, Cinkornpumin, J, Hossain, I, Lynes, M D, Zhang, Y, White, A P, Pastor, W A, Chondronikola, M, Sidossis, L, Klein, S, Kralli, A, Cypess, A M, Pedersen, S B, Jessen, N, Tseng, Y-H, Gerhart-Hines, Z, Seale, P, Calebiro, D, Giguère, V & Kazak, L 2022, ' ADRA1A-Gαq signalling potentiates adipocyte thermogenesis through CKB and TNAP ', Nature Metabolism, vol. 4, no. 11, pp. 1459-1473 . https://doi.org/10.1038/s42255-022-00667-w
Nature metabolism, vol 4, iss 11
Noradrenaline (NA) regulates cold-stimulated adipocyte thermogenesis1. Aside from cAMP signalling downstream of β-adrenergic receptor activation, how NA promotes thermogenic output is still not fully understood. Here, we show that coordinated α1-ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f75271e3902dba13b05e89b120cc2b7c
https://curis.ku.dk/ws/files/327321080/s42255_022_00667_w.pdf
https://curis.ku.dk/ws/files/327321080/s42255_022_00667_w.pdf
Autor:
Bozena, Samborska, Dominic G, Roy, Janane F, Rahbani, Mohammed F, Hussain, Eric H, Ma, Russell G, Jones, Lawrence, Kazak
Publikováno v:
Cell reports. 38(9)
The factors that promote T cell expansion are not fully known. Creatine is an abundant circulating metabolite that has recently been implicated in T cell function; however, its cell-autonomous role in immune-cell function is unknown. Here, we show th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a721780996e24fe9699f8f048b50a0ab
https://pubmed.ncbi.nlm.nih.gov/35235777
https://pubmed.ncbi.nlm.nih.gov/35235777
Autor:
Janane F. Rahbani, LeeAnn C Ramsay, Petras P. Dzeja, Danielle Tenen, Gina Z. Lu, Florence Y. Dou, Bruce M. Spiegelman, Song Zhang, Lawrence Kazak, Linus T.-Y. Tsai, Mathieu Lajoie, Evan D. Rosen, Edward T. Chouchani, Ian R. Watson, Mark P. Jedrychowski, Bozena Samborska
Publikováno v:
Nature metabolism
Depleting creatine levels in thermogenic adipocytes by inhibiting creatine biosynthesis reduces thermogenesis and causes obesity. However, whether creatine import from the circulation affects adipocyte thermogenesis is unknown. Here we show that dele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdde5e1727fbf170edcc0690f6179c27
https://doi.org/10.1038/s42255-019-0035-x
https://doi.org/10.1038/s42255-019-0035-x
Autor:
Alex Wang, Caroline R. Kim, Mark P. Jedrychowski, Nelson H. Knudsen, Christopher L. Riley, Yizhi Sun, Xing Zeng, Bruce M. Spiegelman, Sara Vidoni, Bo Hu, Anthony Marasciullo, Lawrence Kazak, José Luis Millán, Janane F. Rahbani, Dina Bogoslavski, Phillip A. Dumesic, Edward T. Chouchani
Publikováno v:
Nature
Adaptive thermogenesis has attracted much attention because of its ability to increase systemic energy expenditure and to counter obesity and diabetes1-3. Recent data have indicated that thermogenic fat cells use creatine to stimulate futile substrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50418d72631edf6344349bda55c496b7
https://europepmc.org/articles/PMC8287965/
https://europepmc.org/articles/PMC8287965/
Autor:
Bozena Samborska, Dominic G. Roy, Janane F. Rahbani, Mohammed F. Hussain, Eric H. Ma, Russell G. Jones, Lawrence Kazak
Publikováno v:
Cell Reports. 38:110446
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47ea498371f56a696ec48237e3b34cf9
https://doi.org/10.1016/j.celrep.2022.110446
https://doi.org/10.1016/j.celrep.2022.110446
Autor:
Christien B. Dykstra, Bozena Samborska, Caroline S. Jiang, Paul Cohen, Lawrence Kazak, Olivia A. Maguire, Janane F. Rahbani, Matthew G. Annis, Xiaojing Huang, Adriana Rosas-Villegas, Sarah K. Szwed, Rebecca G. Gelfer, Peter M. Siegel, François Marchildon, Ji Dung Luo, Raghavendra G. Mirmira, Daniel J. Kramer, Sarah E. Ackerman, Aarthi V. Maganti, Victor Ceballos, Lauren E. Turner, Sarah A. Tersey, Andrew J. Dannenberg, Thomas L. Carroll, Asal Hejazi
Publikováno v:
Cell metabolism. 33(3)
Obesity is a major risk factor for adverse outcomes in breast cancer; however, the underlying molecular mechanisms have not been elucidated. To investigate the role of crosstalk between mammary adipocytes and neoplastic cells in the tumor microenviro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a90988279b23b097e068a2c96f2729
https://pubmed.ncbi.nlm.nih.gov/33657388
https://pubmed.ncbi.nlm.nih.gov/33657388
Autor:
Christien B. Dykstra, Linus T.-Y. Tsai, Karen Reue, Janane F. Rahbani, Laurent Vergnes, Anna Roesler, Lawrence Kazak, Mark P. Jedrychowski, Bozena Samborska, Bruce M. Spiegelman, Mohammed Faiz Hussain
Publikováno v:
Nature
Obesity increases the risk of mortality because of metabolic sequelae such as type 2 diabetes and cardiovascular disease1. Thermogenesis by adipocytes can counteract obesity and metabolic diseases2,3. In thermogenic fat, creatine liberates a molar ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edde8a4ba37f0da3658b9cc6524ff3e7
https://pubmed.ncbi.nlm.nih.gov/33597756
https://pubmed.ncbi.nlm.nih.gov/33597756