Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Janaki Kuruppu"'
Autor:
Julio A. Huapaya, Salina Gairhe, Shreya Kanth, Xin Tian, Cumhur Y. Demirkale, David Regenold, Jian Sun, Nicolas F. Lynch, Renjie Luo, Alisa Forsberg, Robin Dewar, Tauseef Rehman, Willy Li, Janell Krack, Janaki Kuruppu, Etsubdink A. Aboye, Christopher Barnett, Jeffrey R. Strich, Richard Davey, Richard Childs, Daniel Chertow, Joseph A. Kovacs, Parizad Torabi-Parizi, Anthony F. Suffredini
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundLimited data are available describing the effects of SARS-CoV-2 breakthrough infections on the plasma proteome.MethodsPCR-positive SARS-CoV-2 patients, enrolled in a natural history study, underwent analysis of the plasma proteome. A prospe
Externí odkaz:
https://doaj.org/article/42bdd0a358b145c291f0f9a26699d31f
Autor:
Nitin J. Karandikar, Michael R. Betts, Janaki Kuruppu, Mark Connors, Laura E. Crotty, Brenna J. Hill, Mario Roederer, David R. Ambrozak, Richard A. Koup, Stephen A. Migueles, Joseph P. Casazza, Daniel C. Douek, Jason M. Brenchley
Publikováno v:
Blood. 101:2711-2720
Virus-specific CD8(+) T-cell responses play a pivotal role in limiting viral replication. Alterations in these responses, such as decreased cytolytic function, inappropriate maturation, and limited proliferative ability could reduce their ability to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc052aaac7a637ac2b4861691947de4f
https://doi.org/10.1182/blood-2002-07-2103
https://doi.org/10.1182/blood-2002-07-2103
Publikováno v:
The Journal of Emergency Medicine. 18:355-359
Cardiogenic shock is one of the most dramatic presentations in Emergency Medicine and requires rapid and accurate assessment, evaluation, and treatment. The cardiovascular disasters that present with shock include acute myocardial infarction with pum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1267b8cdc1420b654fa1e64911dfde2
https://doi.org/10.1016/s0736-4679(99)00228-0
https://doi.org/10.1016/s0736-4679(99)00228-0
Publikováno v:
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 17(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::999f9b4e0ca9e6dab9d0d9de2e0007e2
https://pubmed.ncbi.nlm.nih.gov/23522636
https://pubmed.ncbi.nlm.nih.gov/23522636
Autor:
Janaki Kuruppu, David Price, Javaidia Yazdani, Joseph P. Casazza, Stephen A. Migueles, Francisco J. Guenaga, Jason M. Brenchley, David R. Ambrozak, Mario Roederer, Daniel C. Douek, Richard A. Koup, Brenna J. Hill, Mark Connors
Publikováno v:
Journal of virology. 78(3)
Identification of T-cell subsets that are infected in vivo is essential to understanding the pathogenesis of human immunodeficiency virus (HIV) disease; however, this goal has been beset with technical challenges. Here, we used polychromatic flow cyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98f6a831119ad52bb766f7fc4f8a7010
https://pubmed.ncbi.nlm.nih.gov/14722271
https://pubmed.ncbi.nlm.nih.gov/14722271
Autor:
Mario Roederer, Robert A. Seder, Soorena Khojasteh, Richard A. Koup, Karin Loré, Jason M. Brenchley, Michael R. Betts, Stephen P. Perfetto, Janaki Kuruppu
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 171(8)
Optimal Ag targeting and activation of APCs, especially dendritic cells (DCs), are important in vaccine development. In this study, we report the effects of different Toll-like receptor (TLR)-binding compounds to enhance immune responses induced by h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9878cbd1836b0a04dde4d7c354577ddf
https://pubmed.ncbi.nlm.nih.gov/14530357
https://pubmed.ncbi.nlm.nih.gov/14530357
Autor:
Mark Dybul, David Price, Brenna J. Hill, Joseph P. Casazza, Richard A. Koup, Mark Connors, Daniel C. Douek, Steven M. Wolinsky, Yukari Okamoto, Michael R. Betts, David R. Ambrozak, Zvi Grossman, Kevin J. Kunstman, Annette Oxenius, Janaki Kuruppu, Jason M. Brenchley
Publikováno v:
Nature. 417(6884)
HIV infection is associated with the progressive loss of CD4(+) T cells through their destruction or decreased production. A central, yet unresolved issue of HIV disease is the mechanism for this loss, and in particular whether HIV-specific CD4(+) T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f19e36a0c295a86966c08534e962221
https://pubmed.ncbi.nlm.nih.gov/11986671
https://pubmed.ncbi.nlm.nih.gov/11986671
Publikováno v:
Clinical Medicine Insights: Therapeutics, Vol 1 (2009)
Sustained inhibition of HIV-1, the goal of antiretroviral therapy, is often impeded by the emergence of viral drug resistance. For patients infected with HIV-1 resistant to conventional drugs from the viral reverse transcriptase and protease inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68a5b1221a1140f82946bf7785abbe9f
https://doi.org/10.4137/cmt.s2365
https://doi.org/10.4137/cmt.s2365
Publikováno v:
American Journal of Hematology. 60:249-250
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1f77cae2e1498ccb5b0d026865bcbd9
https://doi.org/10.1002/(sici)1096-8652(199903)60:3<249::aid-ajh20>3.0.co
https://doi.org/10.1002/(sici)1096-8652(199903)60:3<249::aid-ajh20>3.0.co
Publikováno v:
Archives of Internal Medicine. 162:1715
Background Infective endocarditis (IE) is a diagnostic challenge due to its variable presentation and nonspecific clinical findings. The use of transthoracic echocardiography (TTE) has greatly improved the ability to diagnose IE early, and therefore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::863f7936fc4b56fd9095267f3ab73e8a
https://doi.org/10.1001/archinte.162.15.1715
https://doi.org/10.1001/archinte.162.15.1715