Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Janaki Chintapalli"'
Autor:
Krzysztof Reiss, Shuo Yang, Stuart Baskin, Lakshmi Sodagum, Ashwani Malhotra, Janaki Chintapalli, Leonard G. Meggs
Publikováno v:
American Journal of Physiology-Renal Physiology. 289:F1144-F1152
The IGF-1R is a genetic determinant of oxidative stress and longevity. Hyperglycemia induces an exponential increase in the production of a key danger signal, reactive oxygen intermediates, which target genomic DNA. Here, we report for the first time
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f96f5e8bdaf36fc52adbab4e70403c
https://doi.org/10.1152/ajprenal.00094.2005
https://doi.org/10.1152/ajprenal.00094.2005
Autor:
Thu Ho, Jin Ying Wang, Krzysztof Reiss, Janaki Chintapalli, Fernando U. Garcia, Tomasz Skorski, Joanna Trojanek, Tomasz Stoklosa, Maja Grabacka
Publikováno v:
Oncogene. 24:3748-3758
During metastases, cancer cells are temporarily exposed to the condition in which interactions with extracellular environment can be restricted (anchorage-independence). We demonstrate that the sensitivity of prostate cancer cell lines, DU145 and PC-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66a630591aa4f7fcde841120b0848a22
https://doi.org/10.1038/sj.onc.1208537
https://doi.org/10.1038/sj.onc.1208537
Publikováno v:
Oncogene. 22:1124-1134
Recent genetic investigations have established that RhoB gain-of-function is sufficient to mediate the antitransforming effects of farnesyltransferase inhibitors (FTIs) in H-Ras-transformed fibroblast systems. In this study, we addressed the breadth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffbf9112c0e992b78c8973e5a5790f70
https://doi.org/10.1038/sj.onc.1206181
https://doi.org/10.1038/sj.onc.1206181
Autor:
David Opawumi, Leonard G. Meggs, Krzysztof Reiss, Ashwani Malhotra, Janaki Chintapalli, Nazia Shamsuddin, Shuo Yang, Sunita Ray Goyal
Publikováno v:
American journal of physiology. Renal physiology. 292(2)
Hyperglycemia triggers an exponential increase in reactive oxygen species (ROS) at the cellular level. Here, we demonstrate induction of the oxidant-resistant phenotype in mesangial cells by silencing the wild-type (WT) p66ShcA gene. Two approaches w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3f412355a248c924e2a676621408091
https://pubmed.ncbi.nlm.nih.gov/17077388
https://pubmed.ncbi.nlm.nih.gov/17077388
Autor:
Kamel Khalili, Mateusz Koptyra, Janaki Chintapalli, Antonio Giordano, Krzysztof Reiss, Sidney Croul, Jin Ying Wang, Joanna Trojanek, Thu Ho
Publikováno v:
Università degli Studi di Siena-IRIS
The large T-antigen from human polyomavirus JC (JCV T-antigen) is suspected to play a role in malignant transformation. Previously, we reported that JCV T-antigen requires the presence of a functional insulin-like growth factor I receptor (IGF-IR) fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0602c75c7cbf95519ae58ef43df6233b
https://pubmed.ncbi.nlm.nih.gov/16572421
https://pubmed.ncbi.nlm.nih.gov/16572421