Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Janak Raval"'
Autor:
Scott J Dylla, Lucia Beviglia, In-Kyung Park, Cecile Chartier, Janak Raval, Lucy Ngan, Kellie Pickell, Jorge Aguilar, Sasha Lazetic, Stephanie Smith-Berdan, Michael F Clarke, Tim Hoey, John Lewicki, Austin L Gurney
Publikováno v:
PLoS ONE, Vol 3, Iss 6, p e2428 (2008)
Patients generally die of cancer after the failure of current therapies to eliminate residual disease. A subpopulation of tumor cells, termed cancer stem cells (CSC), appears uniquely able to fuel the growth of phenotypically and histologically diver
Externí odkaz:
https://doaj.org/article/ce101979cce848ca91bf3f680f3644ff
Autor:
Scott J. Dylla, Lucia Beviglia, In-Kyung Park, Cecile Chartier, Janak Raval, Lucy Ngan, Kellie Pickell, Jorge Aguilar, Sasha Lazetic, Stephanie Smith-Berdan, Michael F. Clarke, Tim Hoey, John Lewicki, Austin L. Gurney
Publikováno v:
PLoS ONE, Vol 3, Iss 8 (2008)
Externí odkaz:
https://doaj.org/article/11533853fa174d67801558262b738174
Autor:
Austin Gurney, Timothy Hoey, John Lewicki, Ann M. Kapoun, Min Wang, Gilbert O'Young, Belinda Cancilla, Pete Yeung, Wan-Ching Yen, Michelle Stroud, Andrew Lam, May Ji, Jie Wei, Jalpa Shah, Marcus M. Fischer, Shirley Ma, Cristina Dee-Hoskins, Jennifer Cain, Chris Bond, Fumiko Axelrod, Janak Raval, Cecile Chartier
Supplemental figure legends also include brief methods where appropriate.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c92ef1c6e992c263c2057d6a7459f78
https://doi.org/10.1158/0008-5472.22410083.v1
https://doi.org/10.1158/0008-5472.22410083.v1
Autor:
Austin Gurney, Timothy Hoey, John Lewicki, Ann M. Kapoun, Min Wang, Gilbert O'Young, Belinda Cancilla, Pete Yeung, Wan-Ching Yen, Michelle Stroud, Andrew Lam, May Ji, Jie Wei, Jalpa Shah, Marcus M. Fischer, Shirley Ma, Cristina Dee-Hoskins, Jennifer Cain, Chris Bond, Fumiko Axelrod, Janak Raval, Cecile Chartier
Deregulation of the β-catenin signaling has long been associated with cancer. Intracellular components of this pathway, including axin, APC, and β-catenin, are frequently mutated in a range of human tumors, but the contribution of specific extracel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a2dd884372d990c2aeb1d5180b91e4
https://doi.org/10.1158/0008-5472.c.6507911
https://doi.org/10.1158/0008-5472.c.6507911
Autor:
Austin Gurney, Timothy Hoey, John Lewicki, Ann M. Kapoun, Min Wang, Gilbert O'Young, Belinda Cancilla, Pete Yeung, Wan-Ching Yen, Michelle Stroud, Andrew Lam, May Ji, Jie Wei, Jalpa Shah, Marcus M. Fischer, Shirley Ma, Cristina Dee-Hoskins, Jennifer Cain, Chris Bond, Fumiko Axelrod, Janak Raval, Cecile Chartier
Supplemental Tables include a list and brief description of xenograft models used in the study, the RSPO1-4 gene expression profile and beta-catenin activation status of all xenograft models, and the microarray analysis for 4 CRC xenograft models aft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c673aa921f31eb42807e17eb99f932
https://doi.org/10.1158/0008-5472.22410080.v1
https://doi.org/10.1158/0008-5472.22410080.v1
Autor:
Austin Gurney, Timothy Hoey, John Lewicki, Ann M. Kapoun, Min Wang, Gilbert O'Young, Belinda Cancilla, Pete Yeung, Wan-Ching Yen, Michelle Stroud, Andrew Lam, May Ji, Jie Wei, Jalpa Shah, Marcus M. Fischer, Shirley Ma, Cristina Dee-Hoskins, Jennifer Cain, Chris Bond, Fumiko Axelrod, Janak Raval, Cecile Chartier
Supplemental figures include the RSPO gene expression analysis for CRC models, the in vitro testing of anti-RSPO antibodies on RSPO-negative tumors, the IHC analysis of anti-RSPO3+chemo-treated ovarian tumors, the LGR, ZNRF3, and RNF43 gene expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19afe2511ee33ae67efef1d503d78862
https://doi.org/10.1158/0008-5472.22410086.v1
https://doi.org/10.1158/0008-5472.22410086.v1
Autor:
John Lewicki, Andrew Lam, Michelle Stroud, Janak Raval, May Ji, Belinda Cancilla, Jie Wei, Fumiko Takada Axelrod, Gilbert O'Young, Wan-Ching Yen, Min Wang, Timothy Hoey, Ann M. Kapoun, Cecile Chartier, Cristina Dee-Hoskins, Austin L. Gurney, Pete Yeung, Shirley Ma, Christopher J. Bond, Jalpa Shah, Jennifer Cain, Marcus Fischer
Publikováno v:
Cancer research. 76(3)
Deregulation of the β-catenin signaling has long been associated with cancer. Intracellular components of this pathway, including axin, APC, and β-catenin, are frequently mutated in a range of human tumors, but the contribution of specific extracel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4118c1e33a7e59606a7685d6ff967c72
https://pubmed.ncbi.nlm.nih.gov/26719531
https://pubmed.ncbi.nlm.nih.gov/26719531
Autor:
John Lewicki, Austin L. Gurney, Tim Hoey, Lucy Ngan, Lucia Beviglia, Scott J. Dylla, Kellie Pickell, Jorge Aguilar, In-Kyung Park, Mike Clarke, Sasha Lazetic, Cecile Chartier, Janak Raval, Stephanie Smith-Berdan
Publikováno v:
PLoS ONE, Vol 3, Iss 8 (2008)
PLoS ONE
PLoS ONE
In the Materials and Methods section, in the fifth line below the "In Vitro Culture & Cytotoxicity Studies" heading, the correct final concentration of LIF used in this study was 1 x 10e3 u/mL.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a8846661cdeb21f9585a236e3ac2b41
http://europepmc.org/articles/PMC2556496
http://europepmc.org/articles/PMC2556496
Autor:
Cecile Chartier, Ann M. Kapoun, Austin L. Gurney, Cristina Dee-Hoskins, Tim Hoey, Elsa Quintana, Janak Raval, Dragana Antic, Min Wang, Shirley Ma, John Lewicki
Publikováno v:
Cancer Research. 75:2322-2322
Multiple developmental signaling pathways cooperatively regulate cancer stem cell (CSC) function. Among them, the BMP pathway has been implicated in brain CSC tumorigenicity. To examine whether BMP is a general regulator of CSCs across diverse organ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2870a0b6aabcf1dd5dae0176b808b27d
https://doi.org/10.1158/1538-7445.am2015-2322
https://doi.org/10.1158/1538-7445.am2015-2322
Autor:
Jalpa Shah, Jennifer Cain, Christopher J. Bond, Fumiko Takada Axelrod, John Lewicki, Timothy Hoey, Austin L. Gurney, Rene Meisner, Marcus Fischer, Cecile Chartier, Janak Raval, Wan-Ching Yen, Shirley Ma
Publikováno v:
Cancer Research. 74:207-207
Both Notch/Delta-like ligand 4 (DLL4) and vascular endothelial growth factor (VEGF) pathways play a critical role in angiogenesis and tumor growth. Due to differential regulatory effects of VEGF and DLL4 on the vasculature, inhibition of DLL4 or VEGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eac78031ab79dfe7eb0d4c9b53fcbc07
https://doi.org/10.1158/1538-7445.am2014-207
https://doi.org/10.1158/1538-7445.am2014-207