Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Janak L Pathak"'
Autor:
Zhichao Zheng, Lihong Wu, Zhicong Li, Ruoshu Tang, Hongtao Li, Yinyin Huang, Tianqi Wang, Shaofen Xu, Haoyu Cheng, Zhitong Ye, Dong Xiao, Xiaolin Lin, Gang Wu, Richard T Jaspers, Janak L Pathak
Publikováno v:
eLife, Vol 12 (2023)
MicroRNA-155 (miR155) is overexpressed in various inflammatory diseases and cancer, in which bone resorption and osteolysis are frequently observed. However, the role of miR155 on osteogenesis and bone mass phenotype is still unknown. Here, we report
Externí odkaz:
https://doaj.org/article/c9d1c01966474a4094cd8d3dd4343316
Autor:
Yong Huang, Xudong Zhu, Bo Wei, Rongpu Liang, Tianyun Lan, Dongbing Ding, Shengxin Huang, Jun Shao, Zongheng Zheng, Tufeng Chen, Jianpei Liu, Janak L Pathak, Hongbo Wei
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 9 (2022)
Background Onco-immunogenic molecule CD155 is overexpressed in various tumor microenvironments (TME) including in colorectal cancer (CRC). Tumor-associated macrophages (TAMs) are the most abundant immune cells in CRC TME and play a vital role in CRC
Externí odkaz:
https://doaj.org/article/cb77ec1340dc4c8eb996e291ac4b3953
Autor:
Tianjiao Mao, Wei Wei, Bo Chen, Yixin Chen, Shuqi Liang, Guiping Chen, Zhuoyuan Liu, Xiaodan Wu, Lihong Wu, Xiaomeng Li, Nobumoto Watanabe, Kevin H. Mayo, Janak L. Pathak, Jiang Li
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-19 (2024)
Abstract Background Sjögren’s syndrome (SS) is an autoimmune disease with limited effective treatment options. This study aimed to explore the underlying mechanism by which genistein–estrogen receptor alpha (ERα) complex targets X-inactive spec
Externí odkaz:
https://doaj.org/article/6bebd847a44849fcbe01a345c237a6f6
Autor:
Janak L Pathak, Astrid D Bakker, Patrick Verschueren, Willem F Lems, Frank P Luyten, Jenneke Klein-Nulend, Nathalie Bravenboer
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131041 (2015)
Generalized osteoporosis is common in patients with inflammatory diseases, possibly because of circulating inflammatory factors that affect osteoblast and osteoclast formation and activity. Serum levels of the inflammatory factors CXCL8 and CCL20 are
Externí odkaz:
https://doaj.org/article/15d6e0d53a1247208e664a1a2c866c95
Autor:
Huang Wenyan, Zheng Pujue, Huang Yuhang, Liu Zhenni, Wu Yuejun, Wu Wenbin, Li Ziling, Janak L. Pathak, Zeng Sujuan
Publikováno v:
BMC Oral Health, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background As a minimally invasive tool for caries prevention tool, the pulsed erbium:yttrium-aluminum-garnet (Er:YAG) laser is being used in a large number of studies. Microorganisms are extremely vital in the occurrence and development of
Externí odkaz:
https://doaj.org/article/243ffd18296d4e0eb341e5d244a77c77
Autor:
Wei Cao, Jianfeng Jin, Gang Wu, Nathalie Bravenboer, Marco N. Helder, Engelbert A. J. M. Schulten, Rommel G. Bacabac, Janak L. Pathak, Jenneke Klein-Nulend
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Bioactive coatings are promising for improving osseointegration and the long-term success of titanium dental or orthopaedic implants. Biomimetic octacalcium phosphate (OCP) coating can be used as a carrier for osteoinductive agents. κ-Carrageenan, a
Externí odkaz:
https://doaj.org/article/2559097cfc7a45e09e3fec065c994175
Publikováno v:
Materials Today Bio, Vol 15, Iss , Pp 100333- (2022)
Early diagnosis and treatment of oral cancer are vital for patient survival. Since the oral cavity accommodates the second largest and most diverse microbiome community after the gut, the diagnostic and therapeutic approaches with low invasiveness an
Externí odkaz:
https://doaj.org/article/6ed5e9a1f08c41c897dc57275266b18f
Autor:
Sujuan Zeng, Xuedan Zhao, Lingling Zhang, Janak L. Pathak, Wenyan Huang, Yunyang Li, Hongbing Guan, Wanghong Zhao, Lihong Ge, Yan Shu
Publikováno v:
Journal of Biological Engineering, Vol 14, Iss 1, Pp 1-11 (2020)
Abstract The stem cells of human exfoliated deciduous teeth (SHEDs) are considered to be one of the main sources of seed cells in stem cell therapy. The aim of this study was to examine the effect of ciliary neurotrophic factor (CNTF) on neurogenic d
Externí odkaz:
https://doaj.org/article/04b7fd1e401243febf67eaf18ebcbd0a
Autor:
Wei Wei, Tingting Cao, Janak L. Pathak, Xintong Liu, Tianjiao Mao, Nobumoto Watanabe, Xiaomeng Li, Manli Zhang, Jiang Li
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Xerostomia is a common symptom in menopausal women, suggesting the role of sex steroids in disease development. Shreds of literature had reported the potential use of herbal extracts to relieve xerostomia. However, a cocktail of multiple components i
Externí odkaz:
https://doaj.org/article/30e0813a0b22446ca05eee1b2a154020
Autor:
Luxi Yang, Qing Ge, Zhitong Ye, Lijing Wang, Liping Wang, Mubarak Ahmed Mashrah, Janak L. Pathak
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Periodontitis is one of the most prevalent oral inflammatory diseases leading to teeth loss and oral health problems in adults. Periodontitis mainly affects periodontal tissue by affecting the host immune system and bone homeostasis. Moreover, period
Externí odkaz:
https://doaj.org/article/34554f074b2748548ce21aba24f7da7b