Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Janak L Pathak"'
Autor:
Zhichao Zheng, Lihong Wu, Zhicong Li, Ruoshu Tang, Hongtao Li, Yinyin Huang, Tianqi Wang, Shaofen Xu, Haoyu Cheng, Zhitong Ye, Dong Xiao, Xiaolin Lin, Gang Wu, Richard T Jaspers, Janak L Pathak
Publikováno v:
eLife, Vol 12 (2023)
MicroRNA-155 (miR155) is overexpressed in various inflammatory diseases and cancer, in which bone resorption and osteolysis are frequently observed. However, the role of miR155 on osteogenesis and bone mass phenotype is still unknown. Here, we report
Externí odkaz:
https://doaj.org/article/c9d1c01966474a4094cd8d3dd4343316
Autor:
Yong Huang, Xudong Zhu, Bo Wei, Rongpu Liang, Tianyun Lan, Dongbing Ding, Shengxin Huang, Jun Shao, Zongheng Zheng, Tufeng Chen, Jianpei Liu, Janak L Pathak, Hongbo Wei
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 9 (2022)
Background Onco-immunogenic molecule CD155 is overexpressed in various tumor microenvironments (TME) including in colorectal cancer (CRC). Tumor-associated macrophages (TAMs) are the most abundant immune cells in CRC TME and play a vital role in CRC
Externí odkaz:
https://doaj.org/article/cb77ec1340dc4c8eb996e291ac4b3953
Autor:
Antong Wu, Ying Zhang, Wei Cao, Xinhong Wang, Zhiqiang Song, Richard T. Jaspers, Lu Chen, Janak L. Pathak, Qingbin Zhang
Publikováno v:
BMC Oral Health, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Melkersson-Rosenthal syndrome (MRS) is a rare neuro-mucocutaneous disorder characterized by recurrent edema, facial palsies, and nerve dysfunctions often associated with the plicata tongue. Although the etiology of MRS is not well
Externí odkaz:
https://doaj.org/article/4b460219f5ac41eda351b64ba8f2f452
Autor:
Fangqi Liu, Qingqing Wu, Qianwen Liu, Bo Chen, Xintong Liu, Janak L. Pathak, Nobumoto Watanabe, Jiang Li
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Dental pulp stem cells (DPSC) have shown osteogenic and bone regenerative potential. Improving the in situ bone regeneration potential of DPSC is crucial for their application as seed cells during bone defect reconstruction in clinics. This
Externí odkaz:
https://doaj.org/article/d1caa10991494b249ac0b67bc6de78dd
Autor:
Henglong Cao, Jianfeng Lin, Hao Yuan, Zipeng Yang, Min Nie, Janak L. Pathak, Zi-Guo Yuan, Miao Yu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Toxoplasma gondii (T. gondii), an obligate intracellular protozoan parasite, is increasingly recognized for its role in various human diseases, including periodontal diseases. Periodontal diseases comprise a wide range of inflammatory conditions that
Externí odkaz:
https://doaj.org/article/b2ecf67066c34e74b5a016d053afade8
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
IntroductionWith the deepening of the healthcare reform in China, the competition in the sector is becoming fiercer leading to several unintended consequences such as talent turnover, which highly affect hospital development. Taking the case of a spe
Externí odkaz:
https://doaj.org/article/fa8f569389ec437b88e282363a8ee743
Autor:
Janak L Pathak, Astrid D Bakker, Patrick Verschueren, Willem F Lems, Frank P Luyten, Jenneke Klein-Nulend, Nathalie Bravenboer
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131041 (2015)
Generalized osteoporosis is common in patients with inflammatory diseases, possibly because of circulating inflammatory factors that affect osteoblast and osteoclast formation and activity. Serum levels of the inflammatory factors CXCL8 and CCL20 are
Externí odkaz:
https://doaj.org/article/15d6e0d53a1247208e664a1a2c866c95
Autor:
Tianjiao Mao, Bo Chen, Wei Wei, Guiping Chen, Zhuoyuan Liu, Lihong Wu, Xiaomeng Li, Janak L. Pathak, Jiang Li
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e33860- (2024)
Primary Sjögren's Syndrome (pSS) is a systemic autoimmune disease that leads to reduced saliva production, primarily affecting women due to estrogen deficiency. The estrogen receptor α (ERα) plays a crucial role in mediating the expression of the
Externí odkaz:
https://doaj.org/article/ef49a9c2401944c89f2b11b4e6e5b8b5
Autor:
Zhenzhang Li, Lingqing Xu, Wen Luo, Shaoan Zhang, Chunyu Hou, Xiaohong Xu, Xubei Peng, E. Shiju, Janak L. Pathak, Shizhen Zhang, Jiawei Liu, Linhai Li, Yang Li
Publikováno v:
Genes and Diseases, Vol 11, Iss 4, Pp 101030- (2024)
Externí odkaz:
https://doaj.org/article/74c70a81505043a2b7e46e33f710a67c
Autor:
Wenchao Zhong, Janine Neugebauer, Janak L. Pathak, Xingyang Li, Gerard Pals, M. Carola Zillikens, Elisabeth M. W. Eekhoff, Nathalie Bravenboer, Qingbin Zhang, Matthias Hammerschmidt, Brunhilde Wirth, Dimitra Micha
Publikováno v:
Cells, Vol 13, Iss 17, p 1507 (2024)
Plastin-3 (PLS3) encodes T-plastin, an actin-bundling protein mediating the formation of actin filaments by which numerous cellular processes are regulated. Loss-of-function genetic defects in PLS3 are reported to cause X-linked osteoporosis and chil
Externí odkaz:
https://doaj.org/article/4e95f3942500479782e68733c11087da