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Autor:
Sven Christian, Albrecht Schwab, Sven G. Meuth, Otto Lindemann, Sandra Schimmelpfennig, Ilya Kovalenko, Natalia Prevarskaya, Jana Welzig, Kateryna Kondratska, Nikolaj Nielsen, Sarah Sargin, Benedikt Hild, Tobias Ruck
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 469:1567-1577
Pancreatic cancer is characterized by a massive fibrosis (desmoplasia), which is primarily caused by activated pancreatic stellate cells (PSCs). This leads to a hypoxic tumor microenvironment further reinforcing the activation of PSCs by stimulating