Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jana Thomas"'
Autor:
Ariful Haque Abir, Leonie Weckwerth, Artur Wilhelm, Jana Thomas, Clara M. Reichardt, Luis Munoz, Simon Völkl, Uwe Appelt, Markus Mroz, Raluca Niesner, Anja Hauser, Rebecca Sophie Fischer, Katharina Pracht, Hans-Martin Jäck, Georg Schett, Gerhard Krönke, Dirk Mielenz
Publikováno v:
Molecular Metabolism, Vol 87, Iss , Pp 101981- (2024)
Objective: The metabolism of different cells within the same microenvironment can differ and dictate physiological or pathological adaptions. Current single-cell analysis methods of metabolism are not label-free. Methods: The study introduces a label
Externí odkaz:
https://doaj.org/article/5b381a534cf04e8f9f71a6a2532ba488
Autor:
Theresa E.H. Bierling, Amelie Gumann, Shannon R. Ottmann, Sebastian R. Schulz, Leonie Weckwerth, Jana Thomas, Arne Gessner, Magdalena Wichert, Frederic Kuwert, Franziska Rost, Manuela Hauke, Tatjana Freudenreich, Dirk Mielenz, Hans-Martin Jäck, Katharina Pracht
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113739- (2024)
Summary: Glucose uptake increases during B cell activation and antibody-secreting cell (ASC) differentiation, but conflicting findings prevent a clear metabolic profile at different stages of B cell activation. Deletion of the glucose transporter typ
Externí odkaz:
https://doaj.org/article/a98e110be8b745b0865c6927784df68d
Autor:
Jana Thomas, Sharon J. Ooms, Lara J. Mentink, Jan Booij, Marcel G. M. Olde Rikkert, Sebastiaan Overeem, Roy P. C. Kessels, Jurgen A. H. R. Claassen
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-12 (2020)
Abstract Background Recent evidence indicates that disrupted sleep could contribute to the development of Alzheimer’s disease by influencing the production and/or clearance of the amyloid-β protein. We set up a case-control study to investigate th
Externí odkaz:
https://doaj.org/article/4de6a8264a6a491ea8d8ab117a0ce651
Autor:
Dorothea Reimer, Michael Meyer-Hermann, Asylkhan Rakhymzhan, Tobit Steinmetz, Philipp Tripal, Jana Thomas, Martin Boettcher, Dimitrios Mougiakakos, Sebastian R. Schulz, Sophia Urbanczyk, Anja E. Hauser, Raluca A. Niesner, Dirk Mielenz
Publikováno v:
Cell Reports, Vol 32, Iss 6, Pp 108030- (2020)
Summary: Plasma cells secreting affinity-matured antibodies develop in germinal centers (GCs), where B cells migrate persistently and directionally over defined periods of time. How modes of GC B cell migration influence plasma cell development remai
Externí odkaz:
https://doaj.org/article/1b38f80a110a4861a41f6604627db27e
Autor:
Lara J Mentink, Jana Thomas, René J F Melis, Marcel G M Olde Rikkert, Sebastiaan Overeem, Jurgen A H R Claassen
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0237622 (2020)
Study objectivesWhile poor sleep quality has been related to increased risk of Alzheimer's disease, long-time shift workers (maritime pilots) did not manifest evidence of early Alzheimer's disease in a recent study. We explored two hypotheses of poss
Externí odkaz:
https://doaj.org/article/38d8679136c0460894b642c2cfe47897
Publikováno v:
BMJ Open, Vol 9, Iss 6 (2019)
IntroductionEvidence indicates a bidirectional relationship between poor sleep and Alzheimer’s disease (AD). While AD may lead to disruption of normal sleep, poor sleep in itself may play a causal role in the development of AD by influencing the pr
Externí odkaz:
https://doaj.org/article/b4a3bbb95b5a4f888d8ac6938b71bd73
Autor:
Tobit D. Steinmetz, Lena Reimann, Sebastian R. Schulz, Sophia Urbanczyk, Jana Thomas, Ann-Kathrin Himmelreich, Florian Golombek, Kathrin Castiglione, Susanne Brodesser, Bettina Warscheid, Dirk Mielenz
The autophagy-flux-promoting protein TFG (Trk-fused gene) is up-regulated during B cell differentiation into plasma cells and supports survival of CH12 B cells. We hypothesized that quantitative proteomics analysis of CH12tfgKO B cells with intact or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae4d6aa812b0488cc56bae1d9b78d141
https://doi.org/10.1101/2022.09.01.506221
https://doi.org/10.1101/2022.09.01.506221
Autor:
Sebastiaan Overeem, Jurgen A.H.R. Claassen, Jana Thomas, Lara J. Mentink, Sharon Ooms, Marcel G. M. Olde Rikkert, Roy P. C. Kessels, Jan Booij
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-12 (2020)
ALZHEIMERS RESEARCH & THERAPY, 12(1):101. BioMed Central
Alzheimer's Research & Therapy, 12(1):101. BioMed Central
Alzheimer's Research & Therapy, 12
Alzheimer's Research & Therapy, 12, 1
Alzheimer's Research & Therapy
ALZHEIMERS RESEARCH & THERAPY, 12(1):101. BioMed Central
Alzheimer's Research & Therapy, 12(1):101. BioMed Central
Alzheimer's Research & Therapy, 12
Alzheimer's Research & Therapy, 12, 1
Alzheimer's Research & Therapy
BackgroundRecent evidence indicates that disrupted sleep could contribute to the development of Alzheimer’s disease by influencing the production and/or clearance of the amyloid-β protein. We set up a case-control study to investigate the associat
Autor:
Sophia Urbanczyk, Olivier R. Baris, Jörg Hofmann, R. Verena Taudte, Naïg Guegen, Florian Golombek, Kathrin Castiglione, Xianyi Meng, Aline Bozec, Jana Thomas, Leonie Weckwerth, Dimitrios Mougiakakos, Sebastian R. Schulz, Wolfgang Schuh, Ursula Schlötzer-Schrehardt, Tobit D. Steinmetz, Susanne Brodesser, Rudolf J. Wiesner, Dirk Mielenz
Publikováno v:
Cell Reports
Cell Reports, 2022, 39 (10), pp.110912. ⟨10.1016/j.celrep.2022.110912⟩
Cell Reports, 2022, 39 (10), pp.110912. ⟨10.1016/j.celrep.2022.110912⟩
International audience; To elucidate the function of oxidative phosphorylation (OxPhos) during B cell differentiation, we employ CD23Cre-driven expression of the dominant-negative K320E mutant of the mitochondrial helicase Twinkle (DNT). DNT-expressi
Publikováno v:
Journal of Sleep Research, 30, 2
Journal of Sleep Research
Journal of Sleep Research, 30(2):e13068. Wiley-Blackwell
Journal of Sleep Research, 30
Journal of Sleep Research
Journal of Sleep Research, 30(2):e13068. Wiley-Blackwell
Journal of Sleep Research, 30
Contains fulltext : 219405.pdf (Publisher’s version ) (Open Access) Acute total sleep deprivation and partial sleep deprivation have negative impacts on cognitive performance. Studies in subjects who regularly experience sleep loss, however, are ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d747a0c20d73319bc02cbe7708cbfddd
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/219405
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/219405