Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jana Schiefner"'
Publikováno v:
Nucleic Acids Research
Transposable elements amplify in genomes as selfish DNA elements and challenge host fitness because their intrinsic integration steps during mobilization can compromise genome integrity. In gene-dense genomes, transposable elements are notably under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51a7ae0f8d12497f65f89299178bf88a
https://doi.org/10.1093/nar/gky582
https://doi.org/10.1093/nar/gky582
Publikováno v:
Mobile genetic elements. 1(2)
The model species of social amoebae, Dictyostelium discoideum, has a compact genome consisting of about two thirds protein-coding regions, with intergenic regions that are rarely larger than 1,000 bp. We hypothesize that the haploid state of D. disco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab2ef95a8520dbe8c1dcf2d823b1fafc
https://pubmed.ncbi.nlm.nih.gov/22016864
https://pubmed.ncbi.nlm.nih.gov/22016864
Autor:
Ferdinand von Eggeling, Ignacio Rubio, Jana Schiefner, Katrin Schubert, Ute Wittig, Aria Baniahmad, Ivan F. Loncarevic, Melanie Eberhart, Julia Hentschel, Hipler C
Publikováno v:
International Journal of Oncology.
Although the BCR-ABL tyrosine kinase inhibitor Imatinib has undoubtedly revolutionized the therapy of chronic myeloid leukaemia (CML), acquired drug resistance remains a common problem in CML therapy. Resistance often arises from second-line mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c6fcfcc5b8283abc4a4b613544ec48a
https://doi.org/10.3892/ijo.2011.1062
https://doi.org/10.3892/ijo.2011.1062
Publikováno v:
Nucleic Acids Research
Retrotransposons contribute significantly to the evolution of eukaryotic genomes. They replicate by producing DNA copies of their own RNA, which are integrated at new locations in the host cell genome. In the gene-dense genome of the social amoeba Di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d6be8c90750e140630af017ec2054d
https://pubmed.ncbi.nlm.nih.gov/21525131
https://pubmed.ncbi.nlm.nih.gov/21525131
Autor:
Thomas Liehr, Ivan F. Loncarevic, Julia Rosenhahn, Ferdinand von Eggeling, Katrin Schubert, Jana Schiefner, Susanne Michel, Anja Weise, Katrin Hennig, Isabell Hartmann
Publikováno v:
ResearcherID
Approximately 30% of chronic myeloid leukemia patients show initially no response to Imatinib, a potent inhibitor of BCR-ABL. This intrinsic resistance may be due to BCR-ABL-independent cell growth. Here we analysed the cytogenetic anomalies and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f73e36e0649313df1f7d8315e0b17e6
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000247503900014&KeyUID=WOS:000247503900014
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000247503900014&KeyUID=WOS:000247503900014
